| Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma PW Lewis, MM Müller, MS Koletsky, F Cordero, S Lin, LA Banaszynski, ... Science 340 (6134), 857-861, 2013 | 1276 | 2013 |
| Histones: at the crossroads of peptide and protein chemistry MM Müller, TW Muir Chemical reviews 115 (6), 2296-2349, 2015 | 218 | 2015 |
| A rationally designed aldolase foldamer MM Müller, MA Windsor, WC Pomerantz, SH Gellman, D Hilvert Angewandte Chemie (International ed. in English) 48 (5), 922, 2009 | 190 | 2009 |
| ISWI chromatin remodellers sense nucleosome modifications to determine substrate preference GP Dann, GP Liszczak, JD Bagert, MM Müller, UTT Nguyen, F Wojcik, ... Nature 548 (7669), 607-611, 2017 | 172 | 2017 |
| Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries UTT Nguyen, L Bittova, MM Müller, B Fierz, Y David, B Houck-Loomis, ... Nature methods 11 (8), 834-840, 2014 | 155 | 2014 |
| Post-translational modifications of protein backbones: unique functions, mechanisms, and challenges MM Müller Biochemistry 57 (2), 177-185, 2018 | 154 | 2018 |
| A two-state activation mechanism controls the histone methyltransferase Suv39h1 MM Müller, B Fierz, L Bittova, G Liszczak, TW Muir Nature chemical biology 12 (3), 188-193, 2016 | 114 | 2016 |
| Strategy for “detoxification” of a cancer-derived histone mutant based on mapping its interaction with the methyltransferase PRC2 ZZ Brown, MM Müller, SU Jain, CD Allis, PW Lewis, TW Muir Journal of the American Chemical Society 136 (39), 13498-13501, 2014 | 103 | 2014 |
| HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome C Jenness, S Giunta, MM Müller, H Kimura, TW Muir, H Funabiki Proceedings of the National Academy of Sciences 115 (5), E876-E885, 2018 | 100 | 2018 |
| Histone H3 tail binds a unique sensing pocket in EZH2 to activate the PRC2 methyltransferase KS Jani, SU Jain, EJ Ge, KL Diehl, SM Lundgren, MM Müller, PW Lewis, ... Proceedings of the National Academy of Sciences 116 (17), 8295-8300, 2019 | 88 | 2019 |
| Evidence that ubiquitylated H2B corrals hDot1L on the nucleosomal surface to induce H3K79 methylation L Zhou, MT Holt, N Ohashi, A Zhao, MM Müller, B Wang, TW Muir Nature communications 7, doi:10.1038/ncomms10589, 2016 | 75 | 2016 |
| Building proficient enzymes with foldamer prostheses C Mayer, MM Müller, SH Gellman, D Hilvert Angewandte Chemie International Edition 53 (27), 6978-6981, 2014 | 57 | 2014 |
| Enhancing activity and controlling stereoselectivity in a designed PLP-dependent aldolase MD Toscano, MM Müller, D Hilvert Angewandte Chemie-International Edition 46 (24), 4468-4470, 2007 | 45 | 2007 |
| Directed evolution of a model primordial enzyme provides insights into the development of the genetic code MM Müller, JR Allison, N Hongdilokkul, L Gaillon, P Kast, ... PLoS genetics 9 (1), e1003187, 2013 | 35 | 2013 |
| Design, selection, and characterization of a split chorismate mutase MM Müller, H Kries, E Csuhai, P Kast, D Hilvert Protein science 19 (5), 1000-1010, 2010 | 30 | 2010 |
| DNA-guided establishment of nucleosome patterns within coding regions of a eukaryotic genome LY Bey, MM Muller, TW Muir, N Kaplan, LF Landweber Genome Research 25 (11), 1727-1738, 2015 | 29 | 2015 |
| Targeted histone peptides: Insights into the spatial regulation of the methyltransferase PRC2 by using a surrogate of heterotypic chromatin ZZ Brown, MM Müller, HE Kong, PW Lewis, TW Muir Angewandte Chemie International Edition 54 (22), 6457-6461, 2015 | 23 | 2015 |
| Nucleation and propagation of heterochromatin by the histone methyltransferase PRC2: geometric constraints and impact of the regulatory subunit JARID2 EJ Ge, KS Jani, KL Diehl, MM Müller, TW Muir Journal of the American Chemical Society 141 (38), 15029-15039, 2019 | 17 | 2019 |
| Cancer treatment goes viral: Using viral proteins to induce tumour-specific cell death J Wyatt, MM Müller, M Tavassoli Cancers 11 (12), 1975, 2019 | 14 | 2019 |
| Semisynthetic ‘designer’p53 sheds light on a phosphorylation–acetylation relay S Margiola, K Gerecht, MM Müller Chemical Science 12 (24), 8563-8570, 2021 | 10 | 2021 |
