Anja Lux
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Regulation of autoantibody activity by the IL-23–TH17 axis determines the onset of autoimmune disease
R Pfeifle, T Rothe, N Ipseiz, HU Scherer, S Culemann, U Harre, ...
Nature immunology 18 (1), 104, 2017
2152017
Impact of immune complex size and glycosylation on IgG binding to human FcγRs
A Lux, X Yu, CN Scanlan, F Nimmerjahn
The Journal of Immunology 190 (8), 4315-4323, 2013
2142013
Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss
U Harre, SC Lang, R Pfeifle, Y Rombouts, S Frühbeißer, K Amara, H Bang, ...
Nature communications 6 (1), 1-11, 2015
1972015
FcγRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo
F Nimmerjahn, A Lux, H Albert, M Woigk, C Lehmann, D Dudziak, P Smith, ...
Proceedings of the National Academy of Sciences 107 (45), 19396-19401, 2010
1632010
FcγR dependent mechanisms of cytotoxic, agonistic, and neutralizing antibody activities
F Nimmerjahn, S Gordan, A Lux
Trends in immunology 36 (6), 325-336, 2015
1432015
Monocyte subsets responsible for immunoglobulin G-dependent effector functions in vivo
M Biburger, S Aschermann, I Schwab, A Lux, H Albert, H Danzer, M Woigk, ...
Immunity 35 (6), 932-944, 2011
1412011
Inflammatory monocytes and Fcγ receptor IV on osteoclasts are critical for bone destruction during inflammatory arthritis in mice
M Seeling, U Hillenhoff, JP David, G Schett, J Tuckermann, A Lux, ...
Proceedings of the National Academy of Sciences 110 (26), 10729-10734, 2013
1402013
The role of sialic acid as a modulator of the anti-inflammatory activity of IgG
S Böhm, I Schwab, A Lux, F Nimmerjahn
Seminars in immunopathology 34 (3), 443-453, 2012
1092012
Human lymphoid organ dendritic cell identity is predominantly dictated by ontogeny, not tissue microenvironment
GF Heidkamp, J Sander, CHK Lehmann, L Heger, N Eissing, A Baranska, ...
Science immunology 1 (6), 2016
892016
Impact of differential glycosylation on IgG activity
A Lux, F Nimmerjahn
Crossroads between Innate and Adaptive Immunity III, 113-124, 2011
882011
IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions
CH Lee, G Romain, W Yan, M Watanabe, W Charab, B Todorova, J Lee, ...
Nature immunology 18 (8), 889, 2017
862017
The Kaposi's sarcoma-associated herpesvirus-encoded vIRF-3 inhibits cellular IRF-5
E Wies, AS Hahn, K Schmidt, C Viebahn, N Rohland, A Lux, T Schellhorn, ...
Journal of Biological Chemistry 284 (13), 8525-8538, 2009
862009
The other side of immunoglobulin G: suppressor of inflammation
S Aschermann, A Lux, A Baerenwaldt, M Biburger, F Nimmerjahn
Clinical & Experimental Immunology 160 (2), 161-167, 2010
852010
Reply to—IVIG pluripotency and the concept of Fc-sialylation: challenges to the scientist
I Schwab, A Lux, F Nimmerjahn
Nature Reviews Immunology 14 (5), 349-349, 2014
722014
Fcγ receptor IIB (FcγRIIB) maintains humoral tolerance in the human immune system in vivo
A Baerenwaldt, A Lux, H Danzer, BM Spriewald, E Ullrich, G Heidkamp, ...
Proceedings of the National Academy of Sciences 108 (46), 18772-18777, 2011
682011
The pro and anti-inflammatory activities of immunoglobulin G
A Lux, S Aschermann, M Biburger, F Nimmerjahn
Annals of the rheumatic diseases 69 (Suppl 1), i92-i96, 2010
562010
Suppression of Fcγ-receptor-mediated antibody effector function during persistent viral infection
DH Yamada, H Elsaesser, A Lux, JM Timmerman, SL Morrison, ...
Immunity 42 (2), 379-390, 2015
552015
A monosaccharide residue is sufficient to maintain mouse and human IgG subclass activity and directs IgG effector functions to cellular Fc receptors
D Kao, H Danzer, M Collin, A Groß, J Eichler, J Stambuk, G Lauc, A Lux, ...
Cell reports 13 (11), 2376-2385, 2015
512015
Of mice and men: the need for humanized mouse models to study human IgG activity in vivo
A Lux, F Nimmerjahn
Journal of clinical immunology 33 (1), 4-8, 2013
492013
How immunoglobulin G antibodies kill target cells: revisiting an old paradigm
M Biburger, A Lux, F Nimmerjahn
Advances in immunology 124, 67-94, 2014
452014
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