Axel Methner
Axel Methner
Professor of Neurology, University Medical Center Mainz
Bestätigte E-Mail-Adresse bei
Zitiert von
Zitiert von
The Cystine/Glutamate Antiporter System xc in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities
J Lewerenz, SJ Hewett, Y Huang, M Lambros, PW Gout, PW Kalivas, ...
Antioxidants & redox signaling 18 (5), 522-555, 2013
Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands
P Joost, A Methner
Genome biology 3, 1-16, 2002
Effects of dimethyl fumarate on neuroprotection and immunomodulation
P Albrecht, I Bouchachia, N Goebels, N Henke, HH Hofstetter, A Issberner, ...
Journal of neuroinflammation 9, 1-10, 2012
Oxytosis/ferroptosis—(Re-) emerging roles for oxidative stress-dependent non-apoptotic cell death in diseases of the central nervous system
J Lewerenz, G Ates, A Methner, M Conrad, P Maher
Frontiers in neuroscience 12, 340915, 2018
Optical coherence tomography in parkinsonian syndromes
P Albrecht, AK Müller, M Südmeyer, S Ferrea, M Ringelstein, E Cohn, ...
PloS one 7 (4), e34891, 2012
Mechanisms of oxidative glutamate toxicity: the glutamate/cystine antiporter system xc as a neuroprotective drug target
P Albrecht, J Lewerenz, S Dittmer, R Noack, P Maher, A Methner
CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2010
Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxone in vitro
J Lewerenz, P Albrecht, MLT Tien, N Henke, S Karumbayaram, ...
Journal of neurochemistry 111 (2), 332-343, 2009
Crucial role for Nox2 and sleep deprivation in aircraft noise-induced vascular and cerebral oxidative stress, inflammation, and gene regulation
S Kröller-Schön, A Daiber, S Steven, M Oelze, K Frenis, S Kalinovic, ...
European Heart Journal 39 (38), 3528-3539, 2018
Cooperative action of glutamate transporters and cystine/glutamate antiporter system Xc protects from oxidative glutamate toxicity
J Lewerenz, M Klein, A Methner
Journal of neurochemistry 98 (3), 916-925, 2006
The role of Ca2+ in cell death caused by oxidative glutamate toxicity and ferroptosis
P Maher, K van Leyen, PN Dey, B Honrath, A Dolga, A Methner
Cell calcium 70, 47-55, 2018
Degeneration of retinal layers in multiple sclerosis subtypes quantified by optical coherence tomography
P Albrecht, M Ringelstein, AK Müller, N Keser, T Dietlein, A Lappas, ...
Multiple Sclerosis Journal 18 (10), 1422-1429, 2012
Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases
NMC Connolly, P Theurey, V Adam-Vizi, NG Bazan, P Bernardi, ...
Cell Death & Differentiation 25 (3), 542-572, 2018
Genetic predisposition in anti‐LGI1 and anti‐NMDA receptor encephalitis
SH Mueller, A Färber, H Prüss, N Melzer, KS Golombeck, T Kümpfel, ...
Annals of neurology 83 (4), 863-869, 2018
Role of the G-protein-coupled receptor GPR12 as high-affinity receptor for sphingosylphosphorylcholine and its expression and function in brain development
A Ignatov, J Lintzel, I Hermans-Borgmeyer, HJ Kreienkamp, P Joost, ...
Journal of Neuroscience 23 (3), 907-914, 2003
Charcot–Marie–Tooth disease CMT4A: GDAP1 increases cellular glutathione and the mitochondrial membrane potential
R Noack, S Frede, P Albrecht, N Henke, A Pfeiffer, K Knoll, T Dehmel, ...
Human molecular genetics 21 (1), 150-162, 2012
The C terminus of Bax inhibitor-1 forms a Ca2+-permeable channel pore
G Bultynck, S Kiviluoto, N Henke, H Ivanova, L Schneider, V Rybalchenko, ...
Journal of Biological Chemistry 287 (4), 2544-2557, 2012
The plasma membrane channel ORAI1 mediates detrimental calcium influx caused by endogenous oxidative stress
N Henke, P Albrecht, I Bouchachia, M Ryazantseva, K Knoll, J Lewerenz, ...
Cell death & disease 4 (1), e470-e470, 2013
TOX3 is a neuronal survival factor that induces transcription depending on the presence of CITED1 or phosphorylated CREB in the transcriptionally active complex
S Dittmer, Z Kovacs, SH Yuan, G Siszler, M Kögl, H Summer, A Geerts, ...
Journal of cell science 124 (2), 252-260, 2011
Optical coherence tomography measures axonal loss in multiple sclerosis independently of optic neuritis
P Albrecht, R Fröhlich, HP Hartung, BC Kieseier, A Methner
Journal of neurology 254 (11), 1595-1596, 2007
The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA2+-filling state
DA Lisak, T Schacht, V Enders, J Habicht, S Kiviluoto, J Schneider, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (9), 2104-2114, 2015
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