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Costantino Pitzalis
Costantino Pitzalis
Professor of Experimental Medicine and Rheumatology QMUL
Bestätigte E-Mail-Adresse bei qmul.ac.uk
Titel
Zitiert von
Zitiert von
Jahr
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry
F Zhang, K Wei, K Slowikowski, CY Fonseka, DA Rao, S Kelly, ...
Nature immunology 20 (7), 928-942, 2019
8642019
Ectopic lymphoid-like structures in infection, cancer and autoimmunity
C Pitzalis, GW Jones, M Bombardieri, SA Jones
Nature Reviews Immunology 14 (7), 447-462, 2014
6592014
Lactate regulates metabolic and pro-inflammatory circuits in control of T cell migration and effector functions
R Haas, J Smith, V Rocher-Ros, S Nadkarni, T Montero-Melendez, ...
PLoS biology 13 (7), e1002202, 2015
5942015
Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium
F Humby, M Bombardieri, A Manzo, S Kelly, MC Blades, B Kirkham, ...
PLoS medicine 6 (1), e1, 2009
5382009
Mesenchymal multipotency of adult human periosteal cells demonstrated by single‐cell lineage analysis
C De Bari, F Dell'Accio, J Vanlauwe, J Eyckmans, IM Khan, CW Archer, ...
Arthritis & Rheumatism 54 (4), 1209-1221, 2006
5362006
A monoclonal antibody that detects a novel antigen on endothelial cells that is induced by tumor necrosis factor, IL-1, or lipopolysaccharide.
SM Wellicome, MH Thornhill, C Pitzalis, DS Thomas, JS Lanchbury, ...
Journal of immunology (Baltimore, Md.: 1950) 144 (7), 2558-2565, 1990
3921990
Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis
S Alivernini, L MacDonald, A Elmesmari, S Finlay, B Tolusso, MR Gigante, ...
Nature medicine 26 (8), 1295-1306, 2020
3912020
Lactate buildup at the site of chronic inflammation promotes disease by inducing CD4+ T cell metabolic rewiring
V Pucino, M Certo, V Bulusu, D Cucchi, K Goldmann, E Pontarini, R Haas, ...
Cell metabolism 30 (6), 1055-1074. e8, 2019
3232019
Association of CXCL13 and CCL21 expression with the progressive organization of lymphoid‐like structures in Sjögren's syndrome
F Barone, M Bombardieri, A Manzo, MC Blades, PR Morgan, ...
Arthritis & Rheumatism 52 (6), 1773-1784, 2005
3042005
Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis
SE Headland, HR Jones, LV Norling, A Kim, PR Souza, E Corsiero, ...
Science translational medicine 7 (315), 315ra190-315ra190, 2015
2872015
Systematic microanatomical analysis of CXCL13 and CCL21 in situ production and progressive lymphoid organization in rheumatoid synovitis
A Manzo, S Paoletti, M Carulli, MC Blades, F Barone, G Yanni, ...
European journal of immunology 35 (5), 1347-1359, 2005
2842005
The role of TNF‐α in the pathogenesis of inflammation and joint destruction in rheumatoid arthritis (RA): a study using a human RA/SCID mouse chimera
H Matsuno, K Yudoh, R Katayama, F Nakazawa, M Uzuki, T Sawai, ...
Rheumatology 41 (3), 329-337, 2002
2822002
Molecular portraits of early rheumatoid arthritis identify clinical and treatment response phenotypes
MJ Lewis, MR Barnes, K Blighe, K Goldmann, S Rana, JA Hackney, ...
Cell reports 28 (9), 2455-2470. e5, 2019
2782019
Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells
S Rauber, M Luber, S Weber, L Maul, A Soare, T Wohlfahrt, NY Lin, ...
Nature medicine 23 (8), 938-944, 2017
2742017
Overexpression of interleukin‐23, but not interleukin‐17, as an immunologic signature of subclinical intestinal inflammation in ankylosing spondylitis
F Ciccia, M Bombardieri, A Principato, AR Giardina, C Tripodo, R Porcasi, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2009
2742009
The preferential accumulation of helper‐inducer T lymphocytes in inflammatory lesions: evidence for regulation by selective endothelial and homotypic adhesion
C Pitzalis, G Kingsley, D Haskard, G Panayi
European journal of immunology 18 (9), 1397-1404, 1988
2741988
Randomized controlled trial of rituximab and cost‐effectiveness analysis in treating fatigue and oral dryness in primary Sjögren's syndrome
SJ Bowman, CC Everett, JL O'Dwyer, P Emery, C Pitzalis, WF Ng, ...
Arthritis & Rheumatology 69 (7), 1440-1450, 2017
2732017
In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses
HG Evans, NJ Gullick, S Kelly, C Pitzalis, GM Lord, BW Kirkham, ...
Proceedings of the National Academy of Sciences 106 (15), 6232-6237, 2009
2552009
Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients
F Humby, M Lewis, N Ramamoorthi, JA Hackney, MR Barnes, ...
Annals of the rheumatic diseases 78 (6), 761-772, 2019
2492019
Synovial tissue research: a state-of-the-art review
C Orr, E Vieira-Sousa, DL Boyle, MH Buch, CD Buckley, JD Cañete, ...
Nature Reviews Rheumatology 13 (8), 463-475, 2017
2492017
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