Paul J McLaren
Paul J McLaren
Research Scientist, JC Wilt Infectious Diseases Research Centre, NHRL, PHAC
Verified email at umanitoba.ca
Title
Cited by
Cited by
Year
Defining the role of common variation in the genomic and biological architecture of adult human height
AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ...
Nature genetics 46 (11), 1173-1186, 2014
13952014
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation
International HIV Controllers Study
Science 330 (6010), 1551-1557, 2010
8292010
Exome sequencing and the genetic basis of complex traits
A Kiezun, K Garimella, R Do, NO Stitziel, BM Neale, PJ McLaren, N Gupta, ...
Nature genetics 44 (6), 623, 2012
4222012
Influence of HLA-C expression level on HIV control
R Apps, Y Qi, JM Carlson, H Chen, X Gao, R Thomas, Y Yuki, ...
Science 340 (6128), 87-91, 2013
2702013
Extremely low-coverage sequencing and imputation increases power for genome-wide association studies
B Pasaniuc, N Rohland, PJ McLaren, K Garimella, N Zaitlen, H Li, ...
Nature genetics 44 (6), 631-635, 2012
1902012
Decreased Immune Activation in Resistance to HIV-1 Infection Is Associated with an Elevated Frequency of CD4+CD25+FOXP3+ Regulatory T Cells
CM Card, PJ McLaren, C Wachihi, J Kimani, FA Plummer, KR Fowke
The Journal of infectious diseases 199 (9), 1318-1322, 2009
1882009
Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque
M Rotger, J Dalmau, A Rauch, P McLaren, SE Bosinger, R Martinez, ...
The Journal of clinical investigation 121 (6), 2391-2400, 2011
1822011
GWAS identifies novel susceptibility loci on 6p21. 32 and 21q21. 3 for hepatocellular carcinoma in chronic hepatitis B virus carriers
S Li, J Qian, Y Yang, W Zhao, J Dai, JX Bei, JN Foo, PJ McLaren, Z Li, ...
PLoS Genet 8 (7), e1002791, 2012
1582012
HIV-Exposed Seronegative Commercial Sex Workers Show a Quiescent Phenotype in the CD4+ T Cell Compartment and Reduced Expression of HIV-Dependent …
PJ McLaren, T Blake Ball, C Wachihi, W Jaoko, DJ Kelvin, A Danesh, ...
The Journal of infectious diseases 202 (Supplement_3), S339-S344, 2010
1252010
Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants
ER Holzinger, B Grady, MD Ritchie, HJ Ribaudo, EP Acosta, GD Morse, ...
Pharmacogenetics and genomics 22 (12), 858, 2012
1132012
Guanylate binding protein (GBP) 5 is an interferon-inducible inhibitor of HIV-1 infectivity
C Krapp, D Hotter, A Gawanbacht, PJ McLaren, SF Kluge, CM Stürzel, ...
Cell host & microbe 19 (4), 504-514, 2016
1072016
Polymorphisms in IRF-1 associated with resistance to HIV-1 infection in highly exposed uninfected Kenyan sex workers
TB Ball, H Ji, J Kimani, P McLaren, C Marlin, AVS Hill, FA Plummer
Aids 21 (9), 1091-1101, 2007
1032007
The impact of host genetic variation on infection with HIV-1
PJ McLaren, M Carrington
Nature immunology 16 (6), 577-583, 2015
972015
The role of regulatory T cells in chronic and acute viral infections
Y Keynan, CM Card, PJ McLaren, MR Dawood, K Kasper, KR Fowke
Clinical infectious diseases 46 (7), 1046-1052, 2008
902008
Cohorts for the study of hiv-1—exposed but uninfected individuals: Benefits and limitations
RE Horton, PJ McLaren, K Fowke, J Kimani, TB Ball
The Journal of infectious diseases 202 (Supplement_3), S377-S381, 2010
892010
HIV-1 capture and transmission by dendritic cells: the role of viral glycolipids and the cellular receptor Siglec-1
N Izquierdo-Useros, M Lorizate, PJ McLaren, A Telenti, HG Kräusslich, ...
PLoS Pathog 10 (7), e1004146, 2014
882014
Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls
PJ McLaren, C Coulonges, S Ripke, L Van Den Berg, S Buchbinder, ...
PLoS Pathog 9 (7), e1003515, 2013
882013
A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control
I Bartha, JM Carlson, CJ Brumme, PJ McLaren, ZL Brumme, M John, ...
elife 2, e01123, 2013
862013
Privacy-preserving computation of disease risk by using genomic, clinical, and environmental data
E Ayday, JL Raisaro, PJ McLaren, J Fellay, JP Hubaux
2013 {USENIX} Workshop on Health Information Technologies (HealthTech 13), 2013
812013
Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load
PJ McLaren, C Coulonges, I Bartha, TL Lenz, AJ Deutsch, A Bashirova, ...
Proceedings of the National Academy of Sciences 112 (47), 14658-14663, 2015
772015
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