Recent advances in chitosan-based nanoparticles for oral delivery of macromolecules MC Chen, FL Mi, ZX Liao, CW Hsiao, K Sonaje, MF Chung, LW Hsu, ... Advanced drug delivery reviews 65 (6), 865-879, 2013 | 438 | 2013 |
A review of the prospects for polymeric nanoparticle platforms in oral insulin delivery MC Chen, K Sonaje, KJ Chen, HW Sung Biomaterials 32 (36), 9826-9838, 2011 | 438 | 2011 |
Mechanism and consequence of chitosan-mediated reversible epithelial tight junction opening TH Yeh, LW Hsu, MT Tseng, PL Lee, K Sonjae, YC Ho, HW Sung Biomaterials 32 (26), 6164-6173, 2011 | 355 | 2011 |
Enteric-coated capsules filled with freeze-dried chitosan/poly (γ-glutamic acid) nanoparticles for oral insulin delivery K Sonaje, YJ Chen, HL Chen, SP Wey, JH Juang, HN Nguyen, CW Hsu, ... Biomaterials 31 (12), 3384-3394, 2010 | 338 | 2010 |
In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery K Sonaje, YH Lin, JH Juang, SP Wey, CT Chen, HW Sung Biomaterials 30 (12), 2329-2339, 2009 | 334 | 2009 |
Opening of epithelial tight junctions and enhancement of paracellular permeation by chitosan: microscopic, ultrastructural, and computed-tomographic observations K Sonaje, EY Chuang, KJ Lin, TC Yen, FY Su, MT Tseng, HW Sung Molecular pharmaceutics 9 (5), 1271-1279, 2012 | 251 | 2012 |
Multi-ion-crosslinked nanoparticles with pH-responsive characteristics for oral delivery of protein drugs YH Lin, K Sonaje, KM Lin, JH Juang, FL Mi, HW Yang, HW Sung Journal of Controlled Release 132 (2), 141-149, 2008 | 244 | 2008 |
pH-responsive nanoparticles shelled with chitosan for oral delivery of insulin: from mechanism to therapeutic applications HW Sung, K Sonaje, ZX Liao, LW Hsu, EY Chuang Accounts of Chemical Research 45 (4), 619-629, 2012 | 230 | 2012 |
Biodistribution, pharmacodynamics and pharmacokinetics of insulin analogues in a rat model: oral delivery using pH-responsive nanoparticles vs. subcutaneous injection K Sonaje, KJ Lin, SP Wey, CK Lin, TH Yeh, HN Nguyen, CW Hsu, TC Yen, ... Biomaterials 31 (26), 6849-6858, 2010 | 216 | 2010 |
Protease inhibition and absorption enhancement by functional nanoparticles for effective oral insulin delivery FY Su, KJ Lin, K Sonaje, SP Wey, TC Yen, YC Ho, N Panda, EY Chuang, ... Biomaterials 33 (9), 2801-2811, 2012 | 210 | 2012 |
Oral delivery of peptide drugs using nanoparticles self-assembled by poly (γ-glutamic acid) and a chitosan derivative functionalized by trimethylation FL Mi, YY Wu, YH Lin, K Sonaje, YC Ho, CT Chen, JH Juang, HW Sung Bioconjugate chemistry 19 (6), 1248-1255, 2008 | 185 | 2008 |
Development of biodegradable nanoparticles for oral delivery of ellagic acid and evaluation of their antioxidant efficacy against cyclosporine A-induced nephrotoxicity in rats K Sonaje, JL Italia, G Sharma, V Bhardwaj, K Tikoo, MNVR Kumar Pharmaceutical research 24, 899-908, 2007 | 165 | 2007 |
Effects of chitosan-nanoparticle-mediated tight junction opening on the oral absorption of endotoxins K Sonaje, KJ Lin, MT Tseng, SP Wey, FY Su, EY Chuang, CW Hsu, ... Biomaterials 32 (33), 8712-8721, 2011 | 160 | 2011 |
The characteristics, biodistribution and bioavailability of a chitosan-based nanoparticulate system for the oral delivery of heparin MC Chen, HS Wong, KJ Lin, HL Chen, SP Wey, K Sonaje, YH Lin, ... Biomaterials 30 (34), 6629-6637, 2009 | 135 | 2009 |
The glucose-lowering potential of exendin-4 orally delivered via a pH-sensitive nanoparticle vehicle and effects on subsequent insulin secretion in vivo HN Nguyen, SP Wey, JH Juang, K Sonaje, YC Ho, EY Chuang, CW Hsu, ... Biomaterials 32 (10), 2673-2682, 2011 | 123 | 2011 |
Self‐assembled pH‐sensitive nanoparticles: a platform for oral delivery of protein drugs K Sonaje, KJ Lin, JJ Wang, FL Mi, CT Chen, JH Juang, HW Sung Advanced Functional Materials 20 (21), 3695-3700, 2010 | 122 | 2010 |
Pharmaceutical composition of peptide drug and enzyme-inhibition compounds H Sung, K Sonaje, H Tu US Patent 8,084,493, 2011 | 96* | 2011 |
Biodegradable in situ gelling system for subcutaneous administration of ellagic acid and ellagic acid loaded nanoparticles: evaluation of their antioxidant potential against … G Sharma, JL Italia, K Sonaje, K Tikoo, MNVR Kumar Journal of Controlled Release 118 (1), 27-37, 2007 | 80 | 2007 |
Polymeric micelle nanocarriers for targeted epidermal delivery of the hedgehog pathway inhibitor vismodegib: Formulation development and cutaneous biodistribution in human skin SG Kandekar, M Singhal, KB Sonaje, YN Kalia Expert opinion on drug delivery 16 (6), 667-674, 2019 | 29 | 2019 |
A potential therapeutic strategy for diabetes and its complications in the form of co-encapsulated antioxidant nanoparticles (NanoCAPs) of ellagic acid and coenzyme Q10 … DV Ratnam, G Chandraiah, K Sonaje, B Viswanad, V Bhardwaj, ... Journal of Biomedical Nanotechnology 4 (1), 33-43, 2008 | 20 | 2008 |