| Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia JL McAuley, F Hornung, KL Boyd, AM Smith, R McKeon, J Bennink, ... Cell host & microbe 2 (4), 240-249, 2007 | 518 | 2007 |
| Kinetics of Coinfection with Influenza A Virus and Streptococcus pneumoniae AM Smith, FR Adler, RM Ribeiro, RN Gutenkunst, JL McAuley, ... PLoS pathogens 9 (3), e1003238, 2013 | 228 | 2013 |
| Influenza A virus infection kinetics: quantitative data and models AM Smith, AS Perelson Wiley Interdisciplinary Reviews: Systems Biology and Medicine 3 (4), 429-445, 2011 | 189 | 2011 |
| Secondary bacterial infections in influenza virus infection pathogenesis AM Smith, JA McCullers Influenza Pathogenesis and Control-Volume I, 327-356, 2014 | 153 | 2014 |
| Mathematical model of a three-stage innate immune response to a pneumococcal lung infection AM Smith, JA McCullers, FR Adler Journal of theoretical biology 276 (1), 106-116, 2011 | 132 | 2011 |
| An accurate two-phase approximate solution to an acute viral infection model AM Smith, FR Adler, AS Perelson Journal of mathematical biology 60, 711-726, 2010 | 98 | 2010 |
| Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics AM Smith, FR Adler, JL McAuley, RN Gutenkunst, RM Ribeiro, ... PLoS computational biology 7 (2), e1001081, 2011 | 89 | 2011 |
| Host‐pathogen kinetics during influenza infection and coinfection: insights from predictive modeling AM Smith Immunological reviews 285 (1), 97-112, 2018 | 70 | 2018 |
| Modeling the viral dynamics of influenza A virus infection AM Smith, RM Ribeiro Critical Reviews™ in Immunology 30 (3), 2010 | 65 | 2010 |
| COVID-19 virtual patient cohort suggests immune mechanisms driving disease outcomes AL Jenner, RA Aogo, S Alfonso, V Crowe, X Deng, AP Smith, PA Morel, ... PLoS pathogens 17 (7), e1009753, 2021 | 64 | 2021 |
| A critical, nonlinear threshold dictates bacterial invasion and initial kinetics during influenza AM Smith, AP Smith Scientific reports 6 (1), 38703, 2016 | 63 | 2016 |
| Influenza virus infection model with density dependence supports biphasic viral decay AP Smith, DJ Moquin, V Bernhauerova, AM Smith Frontiers in microbiology 9, 1554, 2018 | 59 | 2018 |
| Safety, tolerability, pharmacokinetics, and antimalarial efficacy of a novel Plasmodium falciparum ATP4 inhibitor SJ733: a first-in-human and induced blood-stage malaria phase … AH Gaur, JS McCarthy, JC Panetta, RH Dallas, J Woodford, L Tang, ... The Lancet Infectious Diseases 20 (8), 964-975, 2020 | 52 | 2020 |
| Iterative community-driven development of a SARS-CoV-2 tissue simulator M Getz, Y Wang, G An, M Asthana, A Becker, C Cockrell, N Collier, ... BioRxiv, 2020.04. 02.019075, 2020 | 52 | 2020 |
| Dynamically linking influenza virus infection kinetics, lung injury, inflammation, and disease severity MA Myers, AP Smith, LC Lane, DJ Moquin, R Aogo, S Woolard, P Thomas, ... Elife 10, e68864, 2021 | 49 | 2021 |
| The unexpected impact of vaccines on secondary bacterial infections following influenza AM Smith, VC Huber Viral immunology 31 (2), 159-173, 2018 | 39 | 2018 |
| Extracellular vesicles in viral replication and pathogenesis and their potential role in therapeutic intervention A Kumar, S Kodidela, E Tadrous, TJ Cory, CM Walker, AM Smith, ... Viruses 12 (8), 887, 2020 | 31 | 2020 |
| Enhanced IL-1β production is mediated by a TLR2-MYD88-NLRP3 signaling axis during coinfection with influenza A virus and Streptococcus pneumoniae AE Rodriguez, C Bogart, CM Gilbert, JA McCullers, AM Smith, ... PLoS One 14 (2), e0212236, 2019 | 31 | 2019 |
| Validated models of immune response to virus infection AM Smith Current Opinion in Systems Biology 12, 46-52, 2018 | 30 | 2018 |
| Leveraging computational modeling to understand infectious diseases AL Jenner, RA Aogo, CL Davis, AM Smith, M Craig Current Pathobiology Reports 8, 149-161, 2020 | 29 | 2020 |
Alan S PerelsonSenior Fellow, Los Alamos National LaboratoryVerified email at lanl.gov
