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Patrick Loerch
Patrick Loerch
Verified email at gilead.com
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Year
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays
JM Johnson, J Castle, P Garrett-Engele, Z Kan, PM Loerch, CD Armour, ...
Science 302 (5653), 2141-2144, 2003
18182003
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
P Oberdoerffer, S Michan, M McVay, R Mostoslavsky, J Vann, SK Park, ...
Cell 135 (5), 907-918, 2008
9642008
The aging brain
BA Yankner, T Lu, P Loerch
Annu. Rev. Pathol. Mech. Dis. 3, 41-66, 2008
7822008
Experimental annotation of the human genome using microarray technology
DD Shoemaker, EE Schadt, CD Armour, YD He, P Garrett-Engele, ...
Nature 409 (6822), 922-927, 2001
6192001
Evolution of the aging brain transcriptome and synaptic regulation
PM Loerch, T Lu, KA Dakin, JM Vann, A Isaacs, C Geula, J Wang, Y Pan, ...
PloS one 3 (10), e3329, 2008
3502008
Digital transcriptome profiling using selective hexamer priming for cDNA synthesis
CD Armour, JC Castle, R Chen, T Babak, P Loerch, S Jackson, JK Shah, ...
Nature methods 6 (9), 647-649, 2009
2402009
Optimization of oligonucleotide arrays and RNA amplification protocols for analysis of transcript structure and alternative splicing
J Castle, P Garrett-Engele, CD Armour, SJ Duenwald, PM Loerch, ...
Genome Biology 4, 1-13, 2003
1012003
Alternatively spliced isoforms of histone deacetylase 3 (HDAC3)
C Armour, P Loerch, J Castle, J Johnson
US Patent App. 10/745,242, 2004
272004
Pathway-based analysis of genome-wide siRNA screens reveals the regulatory landscape of APP processing
LM Camargo, XD Zhang, P Loerch, RM Caceres, SD Marine, P Uva, ...
PloS one 10 (2), e0115369, 2015
222015
DNA damage-induced alterations in chromatin contribute to genomic integrity and age-related changes in gene expression
P Oberdoerffer, S Michan, M McVay, R Mostoslavsky, J Vann, SK Park, ...
Cell 135 (5), 907, 2008
192008
Correction: Pathway-based analysis of genome-wide siRNA screens reveals the regulatory landscape of app processing
LM Camargo, XD Zhang, P Loerch, RM Caceres, SD Marine, P Uva, ...
Plos one 10 (6), e0129641, 2015
42015
Alternatively spliced isoform of mitotic centromere-associated kinesin (MCAK)
C Armour, J Castle, P Garrett-Engele, Z Kan, P Loerch, N Tsinoremas
US Patent App. 10/942,521, 2006
12006
Alternatively spliced isoforms of sodium channel, voltage gated, type VIII, alpha (SCN8A)
C Armour, J Castle, P Garrett-Engele, Z Kan, P Loerch, N Tsinoremas
US Patent App. 10/942,522, 2005
12005
Evolution of the aging brain transcriptome and synaptic regulation.
PM Loerch, T Lu, KA Dakin, JM Vann, A Isaacs, C Geula, JB Wang, Y Pan, ...
2012
Using mixed effects models to integrate high-dimensional, genomic data and an array-based analysis of the evolution of brain aging
PM Loerch
Harvard University, 2008
2008
Alternatively spliced isoforms of receptor-interacting serine-threonine kinase 2 (RIPK2)
C Armour, J Castle, P Garrett-Engele, Z Kan, P Loerch, N Tsinoremas
US Patent App. 10/901,779, 2005
2005
Novel isoforms of centromere protein E (CENPE)
C Armour, J Castle, P Garrett-Engele, Z Kan, P Loerch, N Tsinoremas
US Patent App. 10/828,985, 2005
2005
Alternatively spliced isoforms of cysteine protease cathepsin K (CTSK)
C Armour, J Castle, P Garrett-Engele, J Johnson, Z Kan, P Loerch
US Patent App. 10/836,897, 2004
2004
Supplemental Data SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging
AH Park, J Stegmuller, A Hafner, P Loerch, SM Wright, KD Mills, A Bonni, ...
Phylogenetic Analysis of Gene Expression in the Aging Brain
P Loerch, T Lu, A Isaacs, C Li, B Yankner
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Articles 1–20