ABCF ATPases involved in protein synthesis, ribosome assembly and antibiotic resistance: structural and functional diversification across the tree of life V Murina, M Kasari, H Takada, M Hinnu, CK Saha, JW Grimshaw, T Seki, ... Journal of molecular biology 431 (18), 3568-3590, 2019 | 107 | 2019 |
A widespread toxin− antitoxin system exploiting growth control via alarmone signaling S Jimmy, CK Saha, T Kurata, C Stavropoulos, SRA Oliveira, A Koh, ... Proceedings of the National Academy of Sciences 117 (19), 10500-10510, 2020 | 92 | 2020 |
Structural basis for antibiotic resistance mediated by the Bacillus subtilis ABCF ATPase VmlR C Crowe-McAuliffe, M Graf, P Huter, H Takada, M Abdelshahid, ... Proceedings of the National Academy of Sciences 115 (36), 8978-8983, 2018 | 91 | 2018 |
Exponential propagation of large circular DNA by reconstitution of a chromosome-replication cycle M Su’etsugu, H Takada, T Katayama, H Tsujimoto Nucleic acids research 45 (20), 11525-11534, 2017 | 69 | 2017 |
The C-terminal RRM/ACT domain is crucial for fine-tuning the activation of ‘long’RelA-SpoT Homolog enzymes by ribosomal complexes H Takada, M Roghanian, V Murina, I Dzhygyr, R Murayama, G Akanuma, ... Frontiers in microbiology 11, 277, 2020 | 50 | 2020 |
Overall shapes of the SMC-ScpAB complex are determined by balance between constraint and relaxation of its structural parts K Kamada, M Su'etsugu, H Takada, M Miyata, T Hirano Structure 25 (4), 603-616. e4, 2017 | 49 | 2017 |
Structural basis for bacterial ribosome-associated quality control by RqcH and RqcP C Crowe-McAuliffe, H Takada, V Murina, C Polte, S Kasvandik, T Tenson, ... Molecular Cell 81 (1), 115-126. e7, 2021 | 45 | 2021 |
A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes H Tamman, K Van Nerom, H Takada, N Vandenberk, D Scholl, ... Nature Chemical Biology 16 (8), 834-840, 2020 | 43 | 2020 |
Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens C Crowe-McAuliffe, V Murina, KJ Turnbull, M Kasari, M Mohamad, C Polte, ... Nature Communications 12 (1), 3577, 2021 | 40 | 2021 |
Expanded roles of two‐component response regulator OmpR in Escherichia coli: genomic SELEX search for novel regulation targets T Shimada, H Takada, K Yamamoto, A Ishihama Genes to Cells 20 (11), 915-931, 2015 | 40 | 2015 |
Essentiality and function of WalK/WalR two-component system: the past, present, and future of research H Takada, H Yoshikawa Bioscience, Biotechnology, and Biochemistry 82 (5), 741-751, 2018 | 36 | 2018 |
An essential enzyme for phospholipid synthesis associates with the Bacillus subtilis divisome H Takada, S Fukushima‐Tanaka, M Morita, Y Kasahara, S Watanabe, ... Molecular microbiology 91 (2), 242-255, 2014 | 34 | 2014 |
Cell motility and biofilm formation in Bacillus subtilis are affected by the ribosomal proteins, S11 and S21 H Takada, M Morita, Y Shiwa, R Sugimoto, S Suzuki, F Kawamura, ... Bioscience, Biotechnology, and Biochemistry 78 (5), 898-907, 2014 | 32 | 2014 |
Ribosome association primes the stringent factor Rel for tRNA-dependent locking in the A-site and activation of (p) ppGpp synthesis H Takada, M Roghanian, J Caballero-Montes, K Van Nerom, S Jimmy, ... Nucleic acids research 49 (1), 444-457, 2021 | 31 | 2021 |
RelA-SpoT Homolog toxins pyrophosphorylate the CCA end of tRNA to inhibit protein synthesis T Kurata, T Brodiazhenko, SRA Oliveira, M Roghanian, Y Sakaguchi, ... Molecular cell 81 (15), 3160-3170. e9, 2021 | 30 | 2021 |
Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics C Crowe-McAuliffe, V Murina, KJ Turnbull, S Huch, M Kasari, H Takada, ... Nature Communications 13 (1), 1860, 2022 | 26 | 2022 |
(p) ppGpp controls stringent factors by exploiting antagonistic allosteric coupling between catalytic domains M Roghanian, K Van Nerom, H Takada, J Caballero-Montes, H Tamman, ... Molecular cell 81 (16), 3310-3322. e6, 2021 | 24 | 2021 |
Essentiality of WalRK for growth in Bacillus subtilis and its role during heat stress H Takada, Y Shiwa, Y Takino, N Osaka, S Ueda, S Watanabe, ... Microbiology 164 (4), 670-684, 2018 | 17 | 2018 |
The Rel stringent factor from Thermus thermophilus: crystallization and X-ray analysis K Van Nerom, H Tamman, H Takada, V Hauryliuk, A Garcia-Pino Acta Crystallographica Section F: Structural Biology Communications 75 (8 …, 2019 | 14 | 2019 |
Expression of Bacillus subtilis ABCF antibiotic resistance factor VmlR is regulated by RNA polymerase pausing, transcription attenuation, translation attenuation … H Takada, ZF Mandell, H Yakhnin, A Glazyrina, S Chiba, T Kurata, ... Nucleic Acids Research 50 (11), 6174-6189, 2022 | 13 | 2022 |