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Dominique Sydow
Dominique Sydow
Cheminformatics Research Scientist, Exscientia
Verified email at exscientia.co.uk
Title
Cited by
Cited by
Year
Advances and challenges in computational target prediction
D Sydow, L Burggraaff, A Szengel, HWT van Vlijmen, AP IJzerman, ...
Journal of chemical information and modeling 59 (5), 1728-1742, 2019
972019
Ligand binding ensembles determine graded agonist efficacies at a G protein-coupled receptor
A Bock, M Bermudez, F Krebs, C Matera, B Chirinda, D Sydow, ...
Journal of Biological Chemistry 291 (31), 16375-16389, 2016
802016
TeachOpenCADD: a teaching platform for computer-aided drug design using open source packages and data
D Sydow, A Morger, M Driller, A Volkamer
Journal of cheminformatics 11, 1-7, 2019
552019
More than a look into a crystal ball: Protein structure elucidation guided by molecular dynamics simulations
M Bermudez, J Mortier, C Rakers, D Sydow, G Wolber
Drug Discovery Today 21 (11), 1799-1805, 2016
522016
Arginase structure and inhibition: catalytic site plasticity reveals new modulation possibilities
J Mortier, JRC Prévost, D Sydow, S Teuchert, C Omieczynski, ...
Scientific Reports 7 (1), 13616, 2017
392017
Molecular insight on the binding of NNRTI to K103N mutated HIV-1 RT: molecular dynamics simulations and dynamic pharmacophore analysis
B Nizami, D Sydow, G Wolber, B Honarparvar
Molecular Biosystems 12 (11), 3385-3395, 2016
272016
TeachOpenCADD-KNIME: a teaching platform for computer-aided drug design using KNIME workflows
D Sydow, M Wichmann, J Rodríguez-Guerra, D Goldmann, G Landrum, ...
Journal of Chemical Information and Modeling 59 (10), 4083-4086, 2019
252019
Ribo-seQC: comprehensive analysis of cytoplasmic and organellar ribosome profiling data
L Calviello, D Sydow, D Harnett, U Ohler
BioRxiv, 601468, 2019
242019
KinFragLib: exploring the kinase inhibitor space using subpocket-focused fragmentation and recombination
D Sydow, P Schmiel, J Mortier, A Volkamer
Journal of Chemical Information and Modeling 60 (12), 6081-6094, 2020
162020
TeachOpenCADD 2022: open source and FAIR Python pipelines to assist in structural bioinformatics and cheminformatics research
D Sydow, J Rodríguez-Guerra, TB Kimber, D Schaller, CJ Taylor, Y Chen, ...
Nucleic Acids Research 50 (W1), W753-W760, 2022
112022
Dynophores: Novel dynamic pharmacophores
D Sydow
Humboldt-Universität zu Berlin, Lebenswissenschaftliche Fakultät, 2015
112015
Ribo-seQC: comprehensive analysis of cytoplasmic and organellar ribosome profiling data. bioRxiv 601468
L Calviello, D Sydow, D Harnett, U Ohler
82019
Dynophores: Novel dynamic pharmacophores implementation of pharmacophore generation based on molecular dynamics trajectories and their graphical representation
D Sydow
Freie Universität Berlin: Berlin, Germany, 2015
82015
Analyzing kinase similarity in small molecule and protein structural space to explore the limits of multi-target screening
D Schmidt, MM Scharf, D Sydow, E Aßmann, M Martí-Solano, M Keul, ...
Molecules 26 (3), 629, 2021
72021
OpenCADD-KLIFS: A Python package to fetch kinase data from the KLIFS database
D Sydow, J Rodríguez-Guerra, A Volkamer
Journal of Open Source Software 7 (70), 3951, 2022
52022
Teaching computer-aided drug design using TeachOpenCADD
D Sydow, J Rodríguez-Guerra, A Volkamer
Teaching Programming across the Chemistry Curriculum, 135-158, 2021
52021
KiSSim: predicting off-targets from structural similarities in the kinome
D Sydow, E Aßmann, AJ Kooistra, F Rippmann, A Volkamer
Journal of Chemical Information and Modeling 62 (10), 2600-2616, 2022
42022
Genome-wide analysis of actively translated open reading frames using RiboTaper/ORFquant
D Harnett, E Meerdink, L Calviello, D Sydow, U Ohler
Ribosome Profiling: Methods and Protocols, 331-346, 2021
32021
105 Stabilization effects induced by modified nucleotides in tRNA T-loop motifs
D Sydow, F Leonarski, L D’Ascenzo, P Auffinger
Journal of Biomolecular Structure and Dynamics 33 (sup1), 66-66, 2015
22015
Kinase Similarity Assessment Pipeline for Off-Target Prediction [Article v1. 0]
TB Kimber, D Sydow, A Volkamer
Living Journal of Computational Molecular Science 3 (1), 1599-1599, 2021
12021
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Articles 1–20