| Advances and challenges in computational target prediction D Sydow, L Burggraaff, A Szengel, HWT van Vlijmen, AP IJzerman, ... Journal of Chemical Information and Modeling 59 (5), 1728-1742, 2019 | 116 | 2019 |
| Ligand binding ensembles determine graded agonist efficacies at a G protein-coupled receptor A Bock, M Bermudez, F Krebs, C Matera, B Chirinda, D Sydow, ... Journal of Biological Chemistry 291 (31), 16375-16389, 2016 | 87 | 2016 |
| TeachOpenCADD: a teaching platform for computer-aided drug design using open source packages and data D Sydow, A Morger, M Driller, A Volkamer Journal of cheminformatics 11, 1-7, 2019 | 62 | 2019 |
| More than a look into a crystal ball: Protein structure elucidation guided by molecular dynamics simulations M Bermudez, J Mortier, C Rakers, D Sydow, G Wolber Drug Discovery Today 21 (11), 1799-1805, 2016 | 53 | 2016 |
| Arginase structure and inhibition: catalytic site plasticity reveals new modulation possibilities J Mortier, JRC Prévost, D Sydow, S Teuchert, C Omieczynski, ... Scientific Reports 7 (1), 13616, 2017 | 41 | 2017 |
| TeachOpenCADD-KNIME: a teaching platform for computer-aided drug design using KNIME workflows D Sydow, M Wichmann, J Rodríguez-Guerra, D Goldmann, G Landrum, ... Journal of Chemical Information and Modeling 59 (10), 4083-4086, 2019 | 31 | 2019 |
| Ribo-seQC: comprehensive analysis of cytoplasmic and organellar ribosome profiling data L Calviello, D Sydow, D Harnett, U Ohler BioRxiv, 601468, 2019 | 28 | 2019 |
| Molecular insight on the binding of NNRTI to K103N mutated HIV-1 RT: molecular dynamics simulations and dynamic pharmacophore analysis B Nizami, D Sydow, G Wolber, B Honarparvar Molecular Biosystems 12 (11), 3385-3395, 2016 | 28 | 2016 |
| KinFragLib: exploring the kinase inhibitor space using subpocket-focused fragmentation and recombination D Sydow, P Schmiel, J Mortier, A Volkamer Journal of Chemical Information and Modeling 60 (12), 6081-6094, 2020 | 17 | 2020 |
| Dynophores: Novel dynamic pharmacophores D Sydow Humboldt-Universität zu Berlin, Lebenswissenschaftliche Fakultät, 2015 | 12 | 2015 |
| TeachOpenCADD 2022: open source and FAIR Python pipelines to assist in structural bioinformatics and cheminformatics research D Sydow, J Rodríguez-Guerra, TB Kimber, D Schaller, CJ Taylor, Y Chen, ... Nucleic Acids Research 50 (W1), W753-W760, 2022 | 11 | 2022 |
| Analyzing kinase similarity in small molecule and protein structural space to explore the limits of multi-target screening D Schmidt, MM Scharf, D Sydow, E Aßmann, M Martí-Solano, M Keul, ... Molecules 26 (3), 629, 2021 | 10 | 2021 |
| Dynophores: Novel dynamic pharmacophores implementation of pharmacophore generation based on molecular dynamics trajectories and their graphical representation D Sydow Freie Universität Berlin: Berlin, Germany, 2015 | 9 | 2015 |
| Ribo-seQC: comprehensive analysis of cytoplasmic and organellar ribosome profiling data. bioRxiv: 601468 L Calviello, D Sydow, D Harnett, U Ohler | 8 | 2019 |
| KiSSim: predicting off-targets from structural similarities in the kinome D Sydow, E Aßmann, AJ Kooistra, F Rippmann, A Volkamer Journal of Chemical Information and Modeling 62 (10), 2600-2616, 2022 | 6 | 2022 |
| OpenCADD-KLIFS: A Python package to fetch kinase data from the KLIFS database D Sydow, J Rodríguez-Guerra, A Volkamer Journal of Open Source Software 7 (70), 3951, 2022 | 5 | 2022 |
| Teaching computer-aided drug design using TeachOpenCADD D Sydow, J Rodríguez-Guerra, A Volkamer Teaching Programming across the Chemistry Curriculum, 135-158, 2021 | 5 | 2021 |
| Genome-wide analysis of actively translated open reading frames using RiboTaper/ORFquant D Harnett, E Meerdink, L Calviello, D Sydow, U Ohler Ribosome Profiling: Methods and Protocols, 331-346, 2021 | 3 | 2021 |
| TeachOpenCADD goes Deep Learning: Open-source Teaching Platform Exploring Molecular DL Applications M Backenköhler, PL Kramer, J Groß, G Großmann, R Joeres, ... | 2 | 2023 |
| 105 Stabilization effects induced by modified nucleotides in tRNA T-loop motifs D Sydow, F Leonarski, L D’Ascenzo, P Auffinger Journal of Biomolecular Structure and Dynamics 33 (sup1), 66-66, 2015 | 2 | 2015 |
