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Qing-Dong Wang
Qing-Dong Wang
Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D
Bestätigte E-Mail-Adresse bei astrazeneca.com
Titel
Zitiert von
Zitiert von
Jahr
Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest
RJ Mills, DM Titmarsh, X Koenig, BL Parker, JG Ryall, GA Quaife-Ryan, ...
Proceedings of the National Academy of Sciences 114 (40), E8372-E8381, 2017
4202017
Pharmacological possibilities for protection against myocardial reperfusion injury
QD Wang, J Pernow, PO Sjöquist, L Rydén
Cardiovascular research 55 (1), 25-37, 2002
2502002
Drug screening in human PSC-cardiac organoids identifies pro-proliferative compounds acting via the mevalonate pathway
RJ Mills, BL Parker, GA Quaife-Ryan, HK Voges, EJ Needham, A Bornot, ...
Cell stem cell 24 (6), 895-907. e6, 2019
2392019
Enhancing the precision of genetic lineage tracing using dual recombinases
L He, Y Li, Y Li, W Pu, X Huang, X Tian, Y Wang, H Zhang, Q Liu, L Zhang, ...
Nature medicine 23 (12), 1488-1498, 2017
2152017
Endothelin in myocardial ischaemia and reperfusion
J Pernow, QD Wang
Cardiovascular research 33 (3), 518-526, 1997
1801997
Preexisting endothelial cells mediate cardiac neovascularization after injury
L He, X Huang, O Kanisicak, Y Li, Y Wang, Y Li, W Pu, Q Liu, H Zhang, ...
The Journal of clinical investigation 127 (8), 2968-2981, 2017
1712017
Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair
L He, W Pu, X Liu, Z Zhang, M Han, YI Li, X Huang, X Han, Y Li, K Liu, ...
Science 371 (6532), eabc4346, 2021
1472021
Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes
Q Liu, R Yang, X Huang, H Zhang, L He, L Zhang, X Tian, Y Nie, S Hu, ...
Cell research 26 (1), 119-130, 2016
1462016
Biocompatible, purified VEGF-A mRNA improves cardiac function after intracardiac injection 1 week post-myocardial infarction in swine
L Carlsson, JC Clarke, C Yen, F Gregoire, T Albery, M Billger, AC Egnell, ...
Molecular Therapy-Methods & Clinical Development 9, 330-346, 2018
1442018
Protective effects of non-peptide endothelin receptor antagonist bosentan on myocardial ischaemic and reperfusion injury in the pig
QD Wang, XS Li, JM Lundberg, J Pernow
Cardiovascular research 29 (6), 805-812, 1995
1161995
Long-term self-renewing human epicardial cells generated from pluripotent stem cells under defined xeno-free conditions
X Bao, X Lian, TA Hacker, EG Schmuck, T Qian, VJ Bhute, T Han, M Shi, ...
Nature biomedical engineering 1 (1), 0003, 2016
1072016
Impedance-based detection of beating rhythm and proarrhythmic effects of compounds on stem cell-derived cardiomyocytes
MKB Jonsson, QD Wang, B Becker
Assay and drug development technologies 9 (6), 589-599, 2011
1042011
Identification of a hybrid myocardial zone in the mammalian heart after birth
X Tian, Y Li, L He, H Zhang, X Huang, Q Liu, W Pu, L Zhang, Y Li, H Zhao, ...
Nature communications 8 (1), 87, 2017
952017
A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting
X Han, Z Zhang, L He, H Zhu, Y Li, W Pu, M Han, H Zhao, K Liu, Y Li, ...
Cell Stem Cell 28 (6), 1160-1176. e7, 2021
812021
Insulin-like growth factor 1 receptor-dependent pathway drives epicardial adipose tissue formation after myocardial injury
L Zangi, MS Oliveira, LY Ye, Q Ma, N Sultana, Y Hadas, E Chepurko, ...
Circulation 135 (1), 59-72, 2017
812017
Local overflow and enhanced tissue content of endothelin following myocardial ischaemia and reperfusion in the pig: modulation by L-arginine
QD Wang, A Hemsén, XS Li, JM Lundberg, Y Uriuda, J Pernow
Cardiovascular research 29 (1), 44-49, 1995
741995
L-arginine enhances functional recovery and Ca2+-dependent nitric oxide synthase activity after ischemia and reperfusion in the rat heart
QD Wang, E Morcos, P Wiklund, J Pernow
Journal of cardiovascular pharmacology 29 (2), 291-296, 1997
681997
Role of l‐arginine in preventing myocardial and endothelial injury following ischaemia/reperfusion in the rat isolated heart
XS Li, Y Uriuda, QD Wang, R Nordlander, PO Sjöquist, J Pernow
Acta Physiologica Scandinavica 156 (1), 37-44, 1996
671996
The protective effect of L-arginine on myocardial injury and endothelial function following ischaemia and reperfusion in the pig
J Pernow, Y Uriuda, QD Wang, XS Li, R Nordlander, L Rydeen
European heart journal 15 (12), 1712-1719, 1994
661994
Beneficial effects of the endothelin receptor antagonist bosentan on myocardial and endothelial injury following ischaemia/reperfusion in the rat
XS Li, QD Wang, J Pernow
European journal of pharmacology 283 (1-3), 161-168, 1995
591995
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