Agata L. Starosta
Agata L. Starosta
Principal Investigator, Institute of Biochemistry and Biophysics Polish Academy of Sciences
Verified email at
Cited by
Cited by
Tetracycline antibiotics and resistance mechanisms
F Nguyen, AL Starosta, S Arenz, D Sohmen, A Dönhöfer, DN Wilson
Biological chemistry 395 (5), 559-575, 2014
Translation Elongation Factor EF-P Alleviates Ribosome Stalling at Polyproline Stretches.
S Ude, J Lassak, AL Starosta, T Kraxenberger, DN Wilson, K Jung
Science 339 (6115), 82-5, 2013
Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites
AH Ratje, J Loerke, A Mikolajka, M Brünner, PW Hildebrand, AL Starosta, ...
Nature 468 (7324), 713-716, 2010
The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
DN Wilson, F Schluenzen, JM Harms, AL Starosta, SR Connell, P Fucini
Proceedings of the National Academy of Sciences 105 (36), 13339-13344, 2008
The bacterial translation stress response
AL Starosta, J Lassak, K Jung, DN Wilson
FEMS microbiology reviews 38 (6), 1172-1201, 2014
Distinct XPPX sequence motifs induce ribosome stalling, which is rescued by the translation elongation factor EF-P
L Peil, AL Starosta, J Lassak, GC Atkinson, K Virumäe, M Spitzer, ...
Proceedings of the National Academy of Sciences 110 (38), 15265-15270, 2013
Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis
L Jenner, AL Starosta, DS Terry, A Mikolajka, ...
Proceedings of the National Academy of Sciences, 2013
Nascent peptides that block protein synthesis in bacteria
CJ Woolstenhulmea, S Parajulia, DW Healeya, DP Valverde, ...
Proceedings of the National Academy of Sciences, 2013
Effect of spastic paraplegia mutations in KIF5A kinesin on transport activity
B Ebbing, K Mann, A Starosta, J Jaud, L Schöls, R Schüle, G Woehlke
Human molecular genetics 17 (9), 1245-1252, 2008
Target-and resistance-based mechanistic studies with TP-434, a novel fluorocycline antibiotic
TH Grossman, AL Starosta, C Fyfe, W O'Brien, DM Rothstein, A Mikolajka, ...
Antimicrobial agents and chemotherapy 56 (5), 2559-2564, 2012
Structural basis for polyproline-mediated ribosome stalling and rescue by the translation elongation factor EF-P
P Huter, S Arenz, LV Bock, M Graf, JO Frister, A Heuer, L Peil, AL Starosta, ...
Molecular cell 68 (3), 515-527. e6, 2017
Arginine-rhamnosylation as new strategy to activate translation elongation factor P
J Lassak, EC Keilhauer, M Fürst, K Wuichet, J Gödeke, AL Starosta, ...
Nature chemical biology 11 (4), 266-270, 2015
The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis
S Arenz, M Abdelshahid, D Sohmen, R Payoe, AL Starosta, ...
Nucleic acids research 44 (13), 6471-6481, 2016
Structural basis for translational stalling by human cytomegalovirus and fungal arginine attenuator peptide
S Bhushan, H Meyer, AL Starosta, T Becker, T Mielke, O Berninghausen, ...
Molecular cell 40 (1), 138-146, 2010
Drug sensing by the ribosome induces translational arrest via active site perturbation
S Arenz, S Meydan, AL Starosta, O Berninghausen, R Beckmann, ...
Molecular cell 56 (3), 446-452, 2014
Entropic contribution of elongation factor P to proline positioning at the catalytic center of the ribosome
LK Doerfel, I Wohlgemuth, V Kubyshkin, AL Starosta, DN Wilson, ...
Journal of the American Chemical Society 137 (40), 12997-13006, 2015
Lys34 of translation elongation factor EF-P is hydroxylated by YfcM
L Peil, AL Starosta, K Virumäe, GC Atkinson, T Tenson, J Remme, ...
Nature chemical biology 8 (8), 695-697, 2012
Distinct tRNA accommodation intermediates observed on the ribosome with the antibiotics hygromycin A and A201A
YS Polikanov, AL Starosta, MF Juette, RB Altman, DS Terry, W Lu, ...
Molecular cell 58 (5), 832-844, 2015
Translational stalling at polyproline stretches is modulated by the sequence context upstream of the stall site
AL Starosta, J Lassak, L Peil, GC Atkinson, K Virumäe, T Tenson, ...
Nucleic acids research 42 (16), 10711-10719, 2014
Interplay between the ribosomal tunnel, nascent chain, and macrolides influences drug inhibition
AL Starosta, VV Karpenko, AV Shishkina, A Mikolajka, NV Sumbatyan, ...
Chemistry & biology 17 (5), 504-514, 2010
The system can't perform the operation now. Try again later.
Articles 1–20