| Disulfiram can inhibit MERS and SARS coronavirus papain-like proteases via different modes MH Lin, DC Moses, CH Hsieh, SC Cheng, YH Chen, CY Sun, CY Chou Antiviral research 150, 155-163, 2018 | 277 | 2018 |
| Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus KW Cheng, SC Cheng, WY Chen, MH Lin, SJ Chuang, IH Cheng, CY Sun, ... Antiviral research 115, 9-16, 2015 | 227 | 2015 |
| Quaternary structure of the severe acute respiratory syndrome (SARS) coronavirus main protease CY Chou, HC Chang, WC Hsu, TZ Lin, CH Lin, GG Chang Biochemistry 43 (47), 14958-14970, 2004 | 151 | 2004 |
| Critical assessment of important regions in the subunit association and catalytic action of the severe acute respiratory syndrome coronavirus main protease WC Hsu, HC Chang, CY Chou, PJ Tsai, PI Lin, GG Chang Journal of Biological Chemistry 280 (24), 22741-22748, 2005 | 124 | 2005 |
| Mutation of Glu-166 blocks the substrate-induced dimerization of SARS coronavirus main protease SC Cheng, GG Chang, CY Chou Biophysical journal 98 (7), 1327-1336, 2010 | 119 | 2010 |
| Crystal structure of murine CstF-77: dimeric association and implications for polyadenylation of mRNA precursors Y Bai, TC Auperin, CY Chou, GG Chang, JL Manley, L Tong Molecular cell 25 (6), 863-875, 2007 | 113 | 2007 |
| The physical forces mediating self-association and phase-separation in the C-terminal domain of TDP-43 HR Li, TC Chen, CL Hsiao, L Shi, CY Chou, J Huang Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1866 (2), 214-223, 2018 | 107 | 2018 |
| Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus CY Chou, CH Chien, YS Han, MT Prebanda, HP Hsieh, B Turk, ... Biochemical pharmacology 75 (8), 1601-1609, 2008 | 107 | 2008 |
| One site mutation disrupts dimer formation in human DPP-IV proteins CH Chien, LH Huang, CY Chou, YS Chen, YS Han, GG Chang, PH Liang, ... Journal of Biological Chemistry 279 (50), 52338-52345, 2004 | 106 | 2004 |
| Thiopurine analogue inhibitors of severe acute respiratory syndrome-coronavirus papain-like protease, a deubiquitinating and deISGylating enzyme X Chen, CY Chou, GG Chang Antiviral Chemistry and Chemotherapy 19 (4), 151-156, 2009 | 90 | 2009 |
| Crystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanism CY Chou, PC Linda, L Tong Journal of biological chemistry 284 (17), 11690-11697, 2009 | 79 | 2009 |
| Uniform GFP-expression in transgenic medaka (Oryzias latipes) at the F0 generation CY Chou, LS Horng, HJ Tsai Transgenic Research 10, 303-315, 2001 | 78 | 2001 |
| Structural variation in human apolipoprotein E3 and E4: secondary structure, tertiary structure, and size distribution CY Chou, YL Lin, YC Huang, SY Sheu, TH Lin, HJ Tsay, GG Chang, ... Biophysical journal 88 (1), 455-466, 2005 | 64 | 2005 |
| Critical assessment of the important residues involved in the dimerization and catalysis of MERS coronavirus main protease BL Ho, SC Cheng, L Shi, TY Wang, KI Ho, CY Chou PLoS One 10 (12), e0144865, 2015 | 60 | 2015 |
| Structural basis for catalysis and ubiquitin recognition by the severe acute respiratory syndrome coronavirus papain-like protease CY Chou, HY Lai, HY Chen, SC Cheng, KW Cheng, YW Chou Acta Crystallographica Section D: Biological Crystallography 70 (2), 572-581, 2014 | 59 | 2014 |
| Structural and functional variations in human apolipoprotein E3 and E4 CY Chou, WP Jen, YH Hsieh, MS Shiao, GG Chang Journal of Biological Chemistry 281 (19), 13333-13344, 2006 | 58 | 2006 |
| Correlation between dissociation and catalysis of SARS-CoV main protease PY Lin, CY Chou, HC Chang, WC Hsu, GG Chang Archives of biochemistry and biophysics 472 (1), 34-42, 2008 | 55 | 2008 |
| Investigation of the dimer interface and substrate specificity of prolyl dipeptidase DPP8 HJ Lee, YS Chen, CY Chou, CH Chien, CH Lin, GG Chang, X Chen Journal of biological chemistry 281 (50), 38653-38662, 2006 | 48 | 2006 |
| 6-Thioguanine is a noncompetitive and slow binding inhibitor of human deubiquitinating protease USP2 SJ Chuang, SC Cheng, HC Tang, CY Sun, CY Chou Scientific Reports 8 (1), 3102, 2018 | 47 | 2018 |
| Structural and functional characterization of MERS coronavirus papain-like protease MH Lin, SJ Chuang, CC Chen, SC Cheng, KW Cheng, CH Lin, CY Sun, ... Journal of biomedical science 21, 1-8, 2014 | 46 | 2014 |
Liang TongDepartment of Biological Sciences, Columbia UniversityBestätigte E-Mail-Adresse bei columbia.edu
