| OPLS discriminant analysis: combining the strengths of PLS‐DA and SIMCA classification M Bylesjö, M Rantalainen, O Cloarec, JK Nicholson, E Holmes, J Trygg Journal of Chemometrics: A Journal of the Chemometrics Society 20 (8‐10 …, 2006 | 1497 | 2006 |
| Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice ME Dumas, RH Barton, A Toye, O Cloarec, C Blancher, A Rothwell, ... Proceedings of the national academy of sciences 103 (33), 12511-12516, 2006 | 1271 | 2006 |
| Pharmaco-metabonomic phenotyping and personalized drug treatment T Andrew Clayton, JC Lindon, O Cloarec, H Antti, C Charuel, G Hanton, ... Nature 440 (7087), 1073-1077, 2006 | 1033 | 2006 |
| Statistical Total Correlation Spectroscopy: An Exploratory Approach for Latent Biomarker Identification from Metabolic 1H NMR Data Sets O Cloarec, ME Dumas, A Craig, RH Barton, J Trygg, J Hudson, ... Analytical chemistry 77 (5), 1282-1289, 2005 | 1012 | 2005 |
| Evaluation of the orthogonal projection on latent structure model limitations caused by chemical shift variability and improved visualization of biomarker changes in 1H NMR … O Cloarec, ME Dumas, J Trygg, A Craig, RH Barton, JC Lindon, ... Analytical chemistry 77 (2), 517-526, 2005 | 657 | 2005 |
| Scaling and normalization effects in NMR spectroscopic metabonomic data sets A Craig, O Cloarec, E Holmes, JK Nicholson, JC Lindon Analytical chemistry 78 (7), 2262-2267, 2006 | 614 | 2006 |
| A top‐down systems biology view of microbiome‐mammalian metabolic interactions in a mouse model FPJ Martin, ME Dumas, Y Wang, C Legido‐Quigley, IKS Yap, H Tang, ... Molecular systems biology 3 (1), 112, 2007 | 592 | 2007 |
| Susceptibility of human metabolic phenotypes to dietary modulation C Stella, B Beckwith-Hall, O Cloarec, E Holmes, JC Lindon, J Powell, ... Journal of proteome research 5 (10), 2780-2788, 2006 | 434 | 2006 |
| Colonization-induced host-gut microbial metabolic interaction SP Claus, SL Ellero, B Berger, L Krause, A Bruttin, J Molina, A Paris, ... MBio 2 (2), 10.1128/mbio. 00271-10, 2011 | 407 | 2011 |
| Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes SP Claus, TM Tsang, Y Wang, O Cloarec, E Skordi, FP Martin, S Rezzi, ... Molecular systems biology 4 (1), 219, 2008 | 396 | 2008 |
| Metabonomic investigations in mice infected with Schistosoma mansoni: an approach for biomarker identification Y Wang, E Holmes, JK Nicholson, O Cloarec, J Chollet, M Tanner, ... Proceedings of the National Academy of Sciences 101 (34), 12676-12681, 2004 | 347 | 2004 |
| Xenobiotic-metabolizing enzymes and transporters in the normal human brain: regional and cellular mapping as a basis for putative roles in cerebral function F Dutheil, S Dauchy, M Diry, V Sazdovitch, O Cloarec, L Mellottée, ... Drug Metabolism and Disposition 37 (7), 1528-1538, 2009 | 197 | 2009 |
| Statistically integrated metabonomic− proteomic studies on a human prostate cancer xenograft model in mice M Rantalainen, O Cloarec, O Beckonert, ID Wilson, D Jackson, R Tonge, ... Journal of proteome research 5 (10), 2642-2655, 2006 | 179 | 2006 |
| Evaluation of a protocol for metabolic profiling studies on human blood plasma by combined ultra-performance liquid chromatography/mass spectrometry: From extraction to data … SJ Bruce, P Jonsson, H Antti, O Cloarec, J Trygg, SL Marklund, T Moritz Analytical Biochemistry 372 (2), 237-249, 2008 | 174 | 2008 |
| Robust data processing and normalization strategy for MALDI mass spectrometric imaging JM Fonville, C Carter, O Cloarec, JK Nicholson, JC Lindon, J Bunch, ... Analytical chemistry 84 (3), 1310-1319, 2012 | 158 | 2012 |
| Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy E Holmes, RL Loo, O Cloarec, M Coen, H Tang, E Maibaum, S Bruce, ... Analytical chemistry 79 (7), 2629-2640, 2007 | 155 | 2007 |
| Development and application of ultra-performance liquid chromatography-TOF MS for precision large scale urinary metabolic phenotyping MR Lewis, JTM Pearce, K Spagou, M Green, AC Dona, AHY Yuen, ... Analytical chemistry 88 (18), 9004-9013, 2016 | 137 | 2016 |
| 1H HR-MAS NMR Spectroscopy of Tumor-Induced Local Metabolic “Field-Effects” Enables Colorectal Cancer Staging and Prognostication B Jiménez, R Mirnezami, J Kinross, O Cloarec, HC Keun, E Holmes, ... Journal of proteome research 12 (2), 959-968, 2013 | 134 | 2013 |
| Chemical mapping of the colorectal cancer microenvironment via MALDI imaging mass spectrometry (MALDI-MSI) reveals novel cancer-associated field effects R Mirnezami, K Spagou, PA Vorkas, MR Lewis, J Kinross, E Want, ... Molecular oncology 8 (1), 39-49, 2014 | 128 | 2014 |
| Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice AA Toye, ME Dumas, C Blancher, AR Rothwell, JF Fearnside, SP Wilder, ... Diabetologia 50, 1867-1879, 2007 | 128 | 2007 |
