Paul Thomas
Paul Thomas
Research Associate Professor
Verified email at northwestern.edu - Homepage
TitleCited byYear
Mapping intact protein isoforms in discovery mode using top-down proteomics
JC Tran, L Zamdborg, DR Ahlf, JE Lee, AD Catherman, KR Durbin, ...
Nature 480 (7376), 254, 2011
5312011
The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t (4; 14) multiple myeloma cells
E Martinez-Garcia, R Popovic, DJ Min, SMM Sweet, PM Thomas, ...
Blood 117 (1), 211-220, 2011
2712011
Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation
JB Shaw, W Li, DD Holden, Y Zhang, J Griep-Raming, RT Fellers, ...
Journal of the American Chemical Society 135 (34), 12646-12651, 2013
2202013
Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic
AL McClerren, LE Cooper, C Quan, PM Thomas, NL Kelleher, ...
Proceedings of the National Academy of Sciences 103 (46), 17243-17248, 2006
2112006
Deconstruction of iterative multidomain polyketide synthase function
JM Crawford, PM Thomas, JR Scheerer, AL Vagstad, NL Kelleher, ...
Science 320 (5873), 243-246, 2008
1972008
Tracking acidic pharmaceuticals, caffeine, and triclosan through the wastewater treatment process
PM Thomas, GD Foster
Environmental Toxicology and Chemistry: An International Journal 24 (1), 25-30, 2005
1872005
Loss of BAP1 function leads to EZH2-dependent transformation
LM LaFave, W Béguelin, R Koche, M Teater, B Spitzer, A Chramiec, ...
Nature medicine 21 (11), 1344, 2015
1432015
Top-down proteomics on a chromatographic time scale using linear ion trap Fourier transform hybrid mass spectrometers
BA Parks, L Jiang, PM Thomas, CD Wenger, MJ Roth, MT Boyne, ...
Analytical chemistry 79 (21), 7984-7991, 2007
1282007
Analysis of intact monoclonal antibody IgG1 by electron transfer dissociation Orbitrap FTMS
L Fornelli, E Damoc, PM Thomas, NL Kelleher, K Aizikov, E Denisov, ...
Molecular & Cellular Proteomics 11 (12), 1758-1767, 2012
1252012
A proteomics approach to discovering natural products and their biosynthetic pathways
SB Bumpus, BS Evans, PM Thomas, I Ntai, NL Kelleher
Nature biotechnology 27 (10), 951, 2009
1252009
On the scalability and requirements of whole protein mass spectrometry
PD Compton, L Zamdborg, PM Thomas, NL Kelleher
Analytical chemistry 83 (17), 6868-6874, 2011
1242011
A protease for'middle-down'proteomics
C Wu, JC Tran, L Zamdborg, KR Durbin, M Li, DR Ahlf, BP Early, ...
Nature methods 9 (8), 822, 2012
1222012
Large-scale top-down proteomics of the human proteome: membrane proteins, mitochondria, and senescence
AD Catherman, KR Durbin, DR Ahlf, BP Early, RT Fellers, JC Tran, ...
Molecular & Cellular Proteomics 12 (12), 3465-3473, 2013
1192013
ProSight Lite: graphical software to analyze top‐down mass spectrometry data
RT Fellers, JB Greer, BP Early, X Yu, RD LeDuc, NL Kelleher, PM Thomas
Proteomics 15 (7), 1235-1238, 2015
1072015
The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput
JF Kellie, JC Tran, JE Lee, DR Ahlf, HM Thomas, I Ntai, AD Catherman, ...
Molecular BioSystems 6 (9), 1532-1539, 2010
972010
Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster
RD Woodyer, Z Shao, PM Thomas, NL Kelleher, JAV Blodgett, ...
Chemistry & biology 13 (11), 1171-1182, 2006
942006
Determination of Nonsteroidal Anti-inflammatory Drugs, Caffeine, and Triclosan in Wastewaterby Gas Chromatography–Mass Spectrometry
PM Thomas, GD Foster
Journal of Environmental Science and Health, Part A 39 (8), 1969-1978, 2004
942004
How many human proteoforms are there?
R Aebersold, JN Agar, IJ Amster, MS Baker, CR Bertozzi, ES Boja, ...
Nature chemical biology 14 (3), 206, 2018
932018
Size-sorting combined with improved nanocapillary liquid chromatography− mass spectrometry for identification of intact proteins up to 80 kDa
A Vellaichamy, JC Tran, AD Catherman, JE Lee, JF Kellie, SMM Sweet, ...
Analytical chemistry 82 (4), 1234-1244, 2010
922010
Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide
JAV Blodgett, PM Thomas, G Li, JE Velasquez, WA Van Der Donk, ...
Nature chemical biology 3 (8), 480, 2007
842007
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Articles 1–20