| New brain tumor entities emerge from molecular classification of CNS-PNETs D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ... Cell 164 (5), 1060-1072, 2016 | 823 | 2016 |
| cIMPACT‐NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT‐Utrecht meeting on future CNS tumor classification and grading DN Louis, P Wesseling, K Aldape, DJ Brat, D Capper, IA Cree, C Eberhart, ... Brain Pathology 30 (4), 844-856, 2020 | 492 | 2020 |
| Vismodegib exerts targeted efficacy against recurrent sonic hedgehog–subgroup medulloblastoma: results from phase II pediatric brain tumor consortium studies PBTC-025B and PBTC-032 GW Robinson, BA Orr, G Wu, S Gururangan, T Lin, I Qaddoumi, ... Journal of Clinical Oncology 33 (24), 2646, 2015 | 460 | 2015 |
| Active medulloblastoma enhancers reveal subgroup-specific cellular origins CY Lin, S Erkek, Y Tong, L Yin, AJ Federation, M Zapatka, P Haldipur, ... Nature 530 (7588), 57-62, 2016 | 390 | 2016 |
| Resolving medulloblastoma cellular architecture by single-cell genomics V Hovestadt, KS Smith, L Bihannic, MG Filbin, MKL Shaw, A Baumgartner, ... Nature 572 (7767), 74-79, 2019 | 324 | 2019 |
| Long interspersed element-1 protein expression is a hallmark of many human cancers N Rodić, R Sharma, R Sharma, J Zampella, L Dai, MS Taylor, RH Hruban, ... The American journal of pathology 184 (5), 1280-1286, 2014 | 292 | 2014 |
| Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition UD Kahlert, D Maciaczyk, S Doostkam, BA Orr, B Simons, T Bogiel, ... Cancer letters 325 (1), 42-53, 2012 | 246 | 2012 |
| Complete clinical regression of a BRAF V600E-mutant pediatric glioblastoma multiforme after BRAF inhibitor therapy GW Robinson, BA Orr, A Gajjar BMC cancer 14, 1-5, 2014 | 206 | 2014 |
| Risk-adapted therapy for young children with medulloblastoma (SJYC07): therapeutic and molecular outcomes from a multicentre, phase 2 trial GW Robinson, VA Rudneva, I Buchhalter, CA Billups, SM Waszak, ... The Lancet Oncology 19 (6), 768-784, 2018 | 201 | 2018 |
| Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma BA Orr, MC Haffner, WG Nelson, S Yegnasubramanian, CG Eberhart PloS one 7 (7), e41036, 2012 | 195 | 2012 |
| Yes-associated protein 1 is widely expressed in human brain tumors and promotes glioblastoma growth BA Orr, H Bai, Y Odia, D Jain, RA Anders, CG Eberhart Journal of Neuropathology & Experimental Neurology 70 (7), 568-577, 2011 | 184 | 2011 |
| Outcomes by clinical and molecular features in children with medulloblastoma treated with risk-adapted therapy: results of an international phase III trial (SJMB03) A Gajjar, GW Robinson, KS Smith, T Lin, TE Merchant, M Chintagumpala, ... Journal of Clinical Oncology 39 (7), 822, 2021 | 136 | 2021 |
| St. Jude Cloud: a pediatric cancer genomic data-sharing ecosystem C McLeod, AM Gout, X Zhou, A Thrasher, D Rahbarinia, SW Brady, ... Cancer discovery 11 (5), 1082-1099, 2021 | 121 | 2021 |
| Irreversible growth plate fusions in children with medulloblastoma treated with a targeted hedgehog pathway inhibitor GW Robinson, SC Kaste, W Chemaitilly, DC Bowers, S Laughton, A Smith, ... Oncotarget 8 (41), 69295, 2017 | 121 | 2017 |
| The molecular landscape of ETMR at diagnosis and relapse S Lambo, SN Gröbner, T Rausch, SM Waszak, C Schmidt, A Gorthi, ... Nature 576 (7786), 274-280, 2019 | 118 | 2019 |
| Genomes for kids: the scope of pathogenic mutations in pediatric cancer revealed by comprehensive DNA and RNA sequencing S Newman, J Nakitandwe, CA Kesserwan, EM Azzato, DA Wheeler, ... Cancer discovery 11 (12), 3008-3027, 2021 | 116 | 2021 |
| Germline elongator mutations in sonic hedgehog medulloblastoma SM Waszak, GW Robinson, BL Gudenas, KS Smith, A Forget, M Kojic, ... Nature 580 (7803), 396-401, 2020 | 116 | 2020 |
| Pathology, diagnostics, and classification of medulloblastoma BA Orr Brain Pathology 30 (3), 664-678, 2020 | 110 | 2020 |
| Neoplastic cells are a rare component in human glioblastoma microvasculature FJ Rodriguez, BA Orr, KL Ligon, CG Eberhart Oncotarget 3 (1), 98, 2012 | 106 | 2012 |
| Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease Z Guo, G Rudow, O Pletnikova, KE Codispoti, BA Orr, BJ Crain, W Duan, ... Movement Disorders 27 (11), 1379-1386, 2012 | 100 | 2012 |
charles eberhartProfessor of Pathology, Ophthalmology and Oncology, Johns Hopkins University School of MedicineBestätigte E-Mail-Adresse bei jhmi.edu
