Constantin Polychronakos
Constantin Polychronakos
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A genome-wide association study identifies novel risk loci for type 2 diabetes
R Sladek, G Rocheleau, J Rung, C Dina, L Shen, D Serre, P Boutin, ...
Nature 445 (7130), 881-885, 2007
Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus
P Vafiadis, ST Bennett, JA Todd, J Nadeau, R Grabs, CG Goodyer, ...
Nature genetics 15 (3), 289-292, 1997
Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations
D Meyre, J Delplanque, JC Chèvre, C Lecoeur, S Lobbens, S Gallina, ...
Nature genetics 41 (2), 157-159, 2009
Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease
DN Cooper, M Krawczak, C Polychronakos, C Tyler-Smith, ...
Human genetics 132, 1077-1130, 2013
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene
H Hakonarson, SFA Grant, JP Bradfield, L Marchand, CE Kim, ...
Nature 448 (7153), 591-594, 2007
Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia
J Rung, S Cauchi, A Albrechtsen, L Shen, G Rocheleau, ...
Nature genetics 41 (10), 1110-1115, 2009
Parental genomic imprinting of the human IGF2 gene
N Giannoukakis, C Deal, J Paquette, CG Goodyer, C Polychronakos
Nature genetics 4 (1), 98-101, 1993
Guidelines for growth hormone and insulin-like growth factor-I treatment in children and adolescents: growth hormone deficiency, idiopathic short stature, and primary insulin …
A Grimberg, SA DiVall, C Polychronakos, DB Allen, LE Cohen, JB Quintos, ...
Hormone Research in Paediatrics 86 (6), 361-397, 2017
Utility of whole‐exome sequencing for those near the end of the diagnostic odyssey: time to address gaps in care
SL Sawyer, T Hartley, DA Dyment, CL Beaulieu, J Schwartzentruber, ...
Clinical genetics 89 (3), 275-284, 2016
A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci
JP Bradfield, HQ Qu, K Wang, H Zhang, PM Sleiman, CE Kim, FD Mentch, ...
PLoS genetics 7 (9), e1002293, 2011
Rfx6 directs islet formation and insulin production in mice and humans
SB Smith, HQ Qu, N Taleb, NY Kishimoto, DW Scheel, Y Lu, AM Patch, ...
Nature 463 (7282), 775-780, 2010
A common autoimmunity predisposing signal peptide variant of the cytotoxic T-lymphocyte antigen 4 results in inefficient glycosylation of the susceptibility allele
S Anjos, A Nguyen, H Ounissi-Benkalha, MC Tessier, C Polychronakos
Journal of Biological Chemistry 277 (48), 46478-46486, 2002
Insulin expression levels in the thymus modulate insulin-specific autoreactive T-cell tolerance: the mechanism by which the IDDM2 locus may predispose to diabetes
AA Chentoufi, C Polychronakos
Diabetes 51 (5), 1383-1390, 2002
Effect of tamoxifen on serum insulinlike growth factor I levels in stage I breast cancer patients
M Pollak, J Costantino, C Polychronakos, SA Blauer, H Guyda, ...
JNCI: Journal of the National Cancer Institute 82 (21), 1693-1697, 1990
A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels
N Bouatia-Naji, G Rocheleau, L Van Lommel, K Lemaire, F Schuit, ...
Science 320 (5879), 1085-1088, 2008
Understanding type 1 diabetes through genetics: advances and prospects
C Polychronakos, Q Li
Nature Reviews Genetics 12 (11), 781-792, 2011
Functional polymorphism in the parental imprinting of the human IGF2R gene
YQ Xu, CG Goodyer, C Deal, C Polychronakos
Biochemical and biophysical research communications 197 (2), 747-754, 1993
From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes
Z Wei, K Wang, HQ Qu, H Zhang, J Bradfield, C Kim, E Frackleton, C Hou, ...
PLoS genetics 5 (10), e1000678, 2009
An imprinted locus associated with transient neonatal diabetes mellitus
RJ Gardner, DJG Mackay, AJ Mungall, C Polychronakos, R Siebert, ...
Human molecular genetics 9 (4), 589-596, 2000
Exome sequencing: dual role as a discovery and diagnostic tool
CS Ku, DN Cooper, C Polychronakos, N Naidoo, M Wu, R Soong
Annals of neurology 71 (1), 5-14, 2012
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