Membrane curvature induction and tubulation are common features of synucleins and apolipoproteins J Varkey, JM Isas, N Mizuno, MB Jensen, VK Bhatia, CC Jao, J Petrlova, ... Journal of Biological Chemistry 285 (42), 32486-32493, 2010 | 394 | 2010 |
Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers V Luibl, JM Isas, R Kayed, CG Glabe, R Langen, J Chen The Journal of clinical investigation 116 (2), 378-385, 2006 | 269 | 2006 |
Fibrillar oligomers nucleate the oligomerization of monomeric amyloid β but do not seed fibril formation JW Wu, L Breydo, JM Isas, J Lee, YG Kuznetsov, R Langen, C Glabe Journal of Biological Chemistry 285 (9), 6071-6079, 2010 | 198 | 2010 |
The S100A10 subunit of the annexin A2 heterotetramer facilitates L2-mediated human papillomavirus infection AW Woodham, DM Da Silva, JG Skeate, AB Raff, MR Ambroso, HE Brand, ... Public Library of Science 7 (8), e43519, 2012 | 191 | 2012 |
Fibril Structure of Human Islet Amyloid Polypeptide*♦ S Bedrood, Y Li, JM Isas, BG Hegde, U Baxa, IS Haworth, R Langen Journal of Biological Chemistry 287 (8), 5235-5241, 2012 | 179 | 2012 |
Soluble and mature amyloid fibrils in drusen deposits JM Isas, V Luibl, LV Johnson, R Kayed, R Wetzel, CG Glabe, R Langen, ... Investigative ophthalmology & visual science 51 (3), 1304-1310, 2010 | 169 | 2010 |
Structure and dynamics of a helical hairpin and loop region in annexin 12: a site-directed spin labeling study JM Isas, R Langen, HT Haigler, WL Hubbell Biochemistry 41 (5), 1464-1473, 2002 | 142 | 2002 |
A transmembrane form of annexin XII detected by site-directed spin labeling R Langen, JM Isas, WL Hubbell, HT Haigler Proceedings of the National Academy of Sciences 95 (24), 14060-14065, 1998 | 133 | 1998 |
Membrane-mediated assembly of annexins studied by site-directed spin labeling R Langen, JM Isas, H Luecke, HT Haigler, WL Hubbell Journal of Biological Chemistry 273 (35), 22453-22457, 1998 | 109 | 1998 |
Annexins V and XII insert into bilayers at mildly acidic pH and form ion channels JM Isas, JP Cartailler, Y Sokolov, DR Patel, R Langen, H Luecke, JE Hall, ... Biochemistry 39 (11), 3015-3022, 2000 | 107 | 2000 |
Structural features and domain organization of huntingtin fibrils CW Bugg, JM Isas, T Fischer, PH Patterson, R Langen Journal of Biological Chemistry 287 (38), 31739-31746, 2012 | 102 | 2012 |
Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin TM Shin, JM Isas, CL Hsieh, R Kayed, CG Glabe, R Langen, J Chen Molecular neurodegeneration 3, 1-12, 2008 | 80 | 2008 |
Hydration dynamics of a peripheral membrane protein O Fisette, C Päslack, R Barnes, JM Isas, R Langen, M Heyden, S Han, ... Journal of the American Chemical Society 138 (36), 11526-11535, 2016 | 70 | 2016 |
Solid-state nuclear magnetic resonance on the static and dynamic domains of huntingtin exon-1 fibrils JM Isas, R Langen, AB Siemer Biochemistry 54 (25), 3942-3949, 2015 | 70 | 2015 |
Determining the membrane topology of proteins: insertion pathway of a transmembrane helix of annexin 12 AS Ladokhin, JM Isas, HT Haigler, SH White Biochemistry 41 (46), 13617-13626, 2002 | 67 | 2002 |
The 17-residue-long N terminus in huntingtin controls stepwise aggregation in solution and on membranes via different mechanisms NK Pandey, JM Isas, A Rawat, RV Lee, J Langen, P Pandey, R Langen Journal of Biological Chemistry 293 (7), 2597-2605, 2018 | 64 | 2018 |
The conserved core domains of annexins A1, A2, A5, and B12 can be divided into two groups with different Ca2+-dependent membrane-binding properties DR Patel, JM Isas, AS Ladokhin, CC Jao, YE Kim, T Kirsch, R Langen, ... Biochemistry 44 (8), 2833-2844, 2005 | 56 | 2005 |
LDL phospholipid hydrolysis produces modified electronegative particles with an unfolded apoB-100 protein L Asatryan, RT Hamilton, JM Isas, J Hwang, R Kayed, A Sevanian Journal of lipid research 46 (1), 115-122, 2005 | 56 | 2005 |
The mitochondrial-derived peptides, HumaninS14G and small Humanin-like peptide 2, exhibit chaperone-like activity AK Okada, K Teranishi, F Lobo, JM Isas, J Xiao, K Yen, P Cohen, ... Scientific reports 7 (1), 7802, 2017 | 54 | 2017 |
LDL protein nitration: implication for LDL protein unfolding RT Hamilton, L Asatryan, JT Nilsen, JM Isas, TK Gallaher, T Sawamura, ... Archives of biochemistry and biophysics 479 (1), 1-14, 2008 | 54 | 2008 |