A role for Schwann cell–derived neuregulin-1 in remyelination RM Stassart, R Fledrich, V Velanac, BG Brinkmann, MH Schwab, D Meijer, ... Nature neuroscience 16 (1), 48-54, 2013 | 299 | 2013 |
Soluble neuregulin-1 modulates disease pathogenesis in rodent models of Charcot-Marie-Tooth disease 1A R Fledrich, RM Stassart, A Klink, LM Rasch, T Prukop, L Haag, D Czesnik, ... Nature medicine 20 (9), 1055-1061, 2014 | 204 | 2014 |
Lithium enhances remyelination of peripheral nerves J Makoukji, M Belle, D Meffre, R Stassart, J Grenier, GG Shackleford, ... Proceedings of the National Academy of Sciences 109 (10), 3973-3978, 2012 | 135 | 2012 |
Redefining the heterogeneity of peripheral nerve cells in health and autoimmunity J Wolbert, X Li, M Heming, AK Mausberg, D Akkermann, C Frydrychowicz, ... Proceedings of the National Academy of Sciences 117 (17), 9466-9476, 2020 | 101 | 2020 |
Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy R Fledrich, T Abdelaal, L Rasch, V Bansal, V Schütza, B Brügger, ... Nature communications 9 (1), 3025, 2018 | 101 | 2018 |
Murine therapeutic models for Charcot-Marie-Tooth (CMT) disease R Fledrich, RM Stassart, MW Sereda British medical bulletin 102 (1), 89-113, 2012 | 96 | 2012 |
Proteome profile of peripheral myelin in healthy mice and in a neuropathy model SB Siems, O Jahn, MA Eichel, N Kannaiyan, LMN Wu, DL Sherman, ... Elife 9, e51406, 2020 | 70 | 2020 |
A rat model of Charcot–Marie–Tooth disease 1A recapitulates disease variability and supplies biomarkers of axonal loss in patients R Fledrich, B Schlotter-Weigel, TJ Schnizer, SP Wichert, RM Stassart, ... Brain 135 (1), 72-87, 2012 | 70 | 2012 |
The Wlds transgene reduces axon loss in a Charcot-Marie-Tooth disease 1A rat model and nicotinamide delays post-traumatic axonal degeneration GM zu Horste, TA Miesbach, JI Muller, R Fledrich, RM Stassart, ... Neurobiology of disease 42 (1), 1-8, 2011 | 64 | 2011 |
NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies R Fledrich, D Akkermann, V Schütza, TA Abdelaal, D Hermes, E Schäffner, ... Nature Communications 10 (1), 1467, 2019 | 59 | 2019 |
Schwann cell functions in peripheral nerve development and repair M Bosch-Queralt, R Fledrich, RM Stassart Neurobiology of disease 176, 105952, 2023 | 52 | 2023 |
Sodium-dependent vitamin C transporter 2 deficiency causes hypomyelination and extracellular matrix defects in the peripheral nervous system B Gess, D Röhr, R Fledrich, MW Sereda, I Kleffner, A Humberg, J Nowitzki, ... Journal of Neuroscience 31 (47), 17180-17192, 2011 | 46 | 2011 |
AAV2/9-mediated silencing of PMP22 prevents the development of pathological features in a rat model of Charcot-Marie-Tooth disease 1 A B Gautier, H Hajjar, S Soares, J Berthelot, M Deck, S Abbou, G Campbell, ... Nature communications 12 (1), 2356, 2021 | 45 | 2021 |
Axo-glial interdependence in peripheral nerve development R Fledrich, T Kungl, KA Nave, RM Stassart Development 146 (21), dev151704, 2019 | 39 | 2019 |
Biomarkers predict outcome in Charcot-Marie-Tooth disease 1A R Fledrich, M Mannil, A Leha, C Ehbrecht, A Solari, AL Pelayo-Negro, ... Journal of Neurology, Neurosurgery & Psychiatry 88 (11), 941-952, 2017 | 34 | 2017 |
Proteolipid protein modulates preservation of peripheral axons and premature death when myelin protein zero is lacking J Patzig, K Kusch, R Fledrich, MA Eichel, KA Lüders, W Möbius, ... Glia 64 (1), 155-174, 2016 | 32 | 2016 |
CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves MA Eichel, VI Gargareta, E D’Este, R Fledrich, T Kungl, TJ Buscham, ... Nature communications 11 (1), 4514, 2020 | 31 | 2020 |
Progesterone antagonist therapy in a Pelizaeus-Merzbacher mouse model T Prukop, DB Epplen, T Nientiedt, SP Wichert, R Fledrich, RM Stassart, ... The American Journal of Human Genetics 94 (4), 533-546, 2014 | 29 | 2014 |
Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease E Schäffner, M Bosch-Queralt, JM Edgar, M Lehning, J Strauß, ... Nature Neuroscience 26 (7), 1218-1228, 2023 | 16 | 2023 |
Early targeting of endoneurial macrophages alleviates the neuropathy and affects abnormal Schwann cell differentiation in a mouse model of Charcot‐Marie‐Tooth 1A D Klein, J Groh, X Yuan, K Berve, R Stassart, R Fledrich, R Martini Glia 70 (6), 1100-1116, 2022 | 12 | 2022 |