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Robert Fledrich
Robert Fledrich
Professor of Neuroanatomy, Institute of Anatomy, Leipzig University
Verified email at medizin.uni-leipzig.de - Homepage
Title
Cited by
Cited by
Year
A role for Schwann cell–derived neuregulin-1 in remyelination
RM Stassart, R Fledrich, V Velanac, BG Brinkmann, MH Schwab, D Meijer, ...
Nature neuroscience 16 (1), 48-54, 2013
2992013
Soluble neuregulin-1 modulates disease pathogenesis in rodent models of Charcot-Marie-Tooth disease 1A
R Fledrich, RM Stassart, A Klink, LM Rasch, T Prukop, L Haag, D Czesnik, ...
Nature medicine 20 (9), 1055-1061, 2014
2042014
Lithium enhances remyelination of peripheral nerves
J Makoukji, M Belle, D Meffre, R Stassart, J Grenier, GG Shackleford, ...
Proceedings of the National Academy of Sciences 109 (10), 3973-3978, 2012
1352012
Redefining the heterogeneity of peripheral nerve cells in health and autoimmunity
J Wolbert, X Li, M Heming, AK Mausberg, D Akkermann, C Frydrychowicz, ...
Proceedings of the National Academy of Sciences 117 (17), 9466-9476, 2020
1012020
Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy
R Fledrich, T Abdelaal, L Rasch, V Bansal, V Schütza, B Brügger, ...
Nature communications 9 (1), 3025, 2018
1012018
Murine therapeutic models for Charcot-Marie-Tooth (CMT) disease
R Fledrich, RM Stassart, MW Sereda
British medical bulletin 102 (1), 89-113, 2012
962012
Proteome profile of peripheral myelin in healthy mice and in a neuropathy model
SB Siems, O Jahn, MA Eichel, N Kannaiyan, LMN Wu, DL Sherman, ...
Elife 9, e51406, 2020
702020
A rat model of Charcot–Marie–Tooth disease 1A recapitulates disease variability and supplies biomarkers of axonal loss in patients
R Fledrich, B Schlotter-Weigel, TJ Schnizer, SP Wichert, RM Stassart, ...
Brain 135 (1), 72-87, 2012
702012
The Wlds transgene reduces axon loss in a Charcot-Marie-Tooth disease 1A rat model and nicotinamide delays post-traumatic axonal degeneration
GM zu Horste, TA Miesbach, JI Muller, R Fledrich, RM Stassart, ...
Neurobiology of disease 42 (1), 1-8, 2011
642011
NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies
R Fledrich, D Akkermann, V Schütza, TA Abdelaal, D Hermes, E Schäffner, ...
Nature Communications 10 (1), 1467, 2019
592019
Schwann cell functions in peripheral nerve development and repair
M Bosch-Queralt, R Fledrich, RM Stassart
Neurobiology of disease 176, 105952, 2023
522023
Sodium-dependent vitamin C transporter 2 deficiency causes hypomyelination and extracellular matrix defects in the peripheral nervous system
B Gess, D Röhr, R Fledrich, MW Sereda, I Kleffner, A Humberg, J Nowitzki, ...
Journal of Neuroscience 31 (47), 17180-17192, 2011
462011
AAV2/9-mediated silencing of PMP22 prevents the development of pathological features in a rat model of Charcot-Marie-Tooth disease 1 A
B Gautier, H Hajjar, S Soares, J Berthelot, M Deck, S Abbou, G Campbell, ...
Nature communications 12 (1), 2356, 2021
452021
Axo-glial interdependence in peripheral nerve development
R Fledrich, T Kungl, KA Nave, RM Stassart
Development 146 (21), dev151704, 2019
392019
Biomarkers predict outcome in Charcot-Marie-Tooth disease 1A
R Fledrich, M Mannil, A Leha, C Ehbrecht, A Solari, AL Pelayo-Negro, ...
Journal of Neurology, Neurosurgery & Psychiatry 88 (11), 941-952, 2017
342017
Proteolipid protein modulates preservation of peripheral axons and premature death when myelin protein zero is lacking
J Patzig, K Kusch, R Fledrich, MA Eichel, KA Lüders, W Möbius, ...
Glia 64 (1), 155-174, 2016
322016
CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves
MA Eichel, VI Gargareta, E D’Este, R Fledrich, T Kungl, TJ Buscham, ...
Nature communications 11 (1), 4514, 2020
312020
Progesterone antagonist therapy in a Pelizaeus-Merzbacher mouse model
T Prukop, DB Epplen, T Nientiedt, SP Wichert, R Fledrich, RM Stassart, ...
The American Journal of Human Genetics 94 (4), 533-546, 2014
292014
Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease
E Schäffner, M Bosch-Queralt, JM Edgar, M Lehning, J Strauß, ...
Nature Neuroscience 26 (7), 1218-1228, 2023
162023
Early targeting of endoneurial macrophages alleviates the neuropathy and affects abnormal Schwann cell differentiation in a mouse model of Charcot‐Marie‐Tooth 1A
D Klein, J Groh, X Yuan, K Berve, R Stassart, R Fledrich, R Martini
Glia 70 (6), 1100-1116, 2022
122022
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