| Distribution of histone deacetylases 1–11 in the rat brain RS Broide, JM Redwine, N Aftahi, W Young, FE Bloom, CJ Winrow Journal of Molecular Neuroscience 31, 47-58, 2007 | 409 | 2007 |
| Discovery of the Dual Orexin Receptor Antagonist [(7R)-4-(5-Chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl … CD Cox, MJ Breslin, DB Whitman, JD Schreier, GB McGaughey, ... Journal of medicinal chemistry 53 (14), 5320-5332, 2010 | 400 | 2010 |
| Orexin receptors: pharmacology and therapeutic opportunities TE Scammell, CJ Winrow Annual review of pharmacology and toxicology 51, 243-266, 2011 | 375 | 2011 |
| Promotion of sleep by suvorexant—a novel dual orexin receptor antagonist CJ Winrow, AL Gotter, CD Cox, SM Doran, PL Tannenbaum, MJ Breslin, ... Journal of neurogenetics 25 (1-2), 52-61, 2011 | 282 | 2011 |
| The concise guide to PHARMACOLOGY 2015/16: Overview SPH Alexander, E Kelly, N Marrion, JA Peters, HE Benson, E Faccenda, ... British journal of pharmacology 172 (24), 5729-5743, 2015 | 241 | 2015 |
| Loss of neuropathy target esterase in mice links organophosphate exposure to hyperactivity CJ Winrow, ML Hemming, DM Allen, GB Quistad, JE Casida, C Barlow Nature genetics 33 (4), 477-485, 2003 | 210 | 2003 |
| Adult mouse brain gene expression patterns bear an embryologic imprint MA Zapala, I Hovatta, JA Ellison, L Wodicka, JA Del Rio, R Tennant, ... Proceedings of the National Academy of Sciences 102 (29), 10357-10362, 2005 | 205 | 2005 |
| Ataxia telangiectasia mutated is essential during adult neurogenesis DM Allen, H van Praag, J Ray, Z Weaver, CJ Winrow, TA Carter, ... Genes & development 15 (5), 554-566, 2001 | 202 | 2001 |
| International Union of Basic and Clinical Pharmacology. LXXXVI. Orexin receptor function, nomenclature and pharmacology AL Gotter, AL Webber, PJ Coleman, JJ Renger, CJ Winrow Pharmacological reviews 64 (3), 389-420, 2012 | 182 | 2012 |
| Discovery and development of orexin receptor antagonists as therapeutics for insomnia CJ Winrow, JJ Renger British journal of pharmacology 171 (2), 283-293, 2014 | 157 | 2014 |
| Evidence that mouse brain neuropathy target esterase is a lysophospholipase GB Quistad, C Barlow, CJ Winrow, SE Sparks, JE Casida Proceedings of the National Academy of Sciences 100 (13), 7983-7987, 2003 | 155 | 2003 |
| Pharmacological characterization of MK-6096–a dual orexin receptor antagonist for insomnia CJ Winrow, AL Gotter, CD Cox, PL Tannenbaum, SL Garson, SM Doran, ... Neuropharmacology 62 (2), 978-987, 2012 | 153 | 2012 |
| Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors J Yin, K Babaoglu, CA Brautigam, L Clark, Z Shao, TH Scheuermann, ... Nature Structural & Molecular Biology 23 (4), 293-299, 2016 | 138 | 2016 |
| Discovery of [(2R,5R)‐5‐{[(5‐Fluoropyridin‐2‐yl)oxy]methyl}‐2‐methylpiperidin‐1‐yl][5‐methyl‐2‐(pyrimidin‐2‐yl)phenyl]methanone (MK‐6096): A Dual Orexin … PJ Coleman, JD Schreier, CD Cox, MJ Breslin, DB Whitman, MJ Bogusky, ... ChemMedChem 7 (3), 415-424, 2012 | 133 | 2012 |
| Orexin receptor antagonism prevents transcriptional and behavioral plasticity resulting from stimulant exposure CJ Winrow, KQ Tanis, DR Reiss, AM Rigby, JM Uslaner, VN Uebele, ... Neuropharmacology 58 (1), 185-194, 2010 | 126 | 2010 |
| Orexin receptors as therapeutic drug targets AL Gotter, AJ Roecker, R Hargreaves, PJ Coleman, CJ Winrow, ... Progress in brain research 198, 163-188, 2012 | 116 | 2012 |
| The discovery of suvorexant, the first orexin receptor drug for insomnia PJ Coleman, AL Gotter, WJ Herring, CJ Winrow, JJ Renger Annual review of pharmacology and toxicology 57, 509-533, 2017 | 112 | 2017 |
| Orexin receptor antagonists differ from standard sleep drugs by promoting sleep at doses that do not disrupt cognition JM Uslaner, SJ Tye, DM Eddins, X Wang, SV Fox, AT Savitz, J Binns, ... Science translational medicine 5 (179), 179ra44-179ra44, 2013 | 105 | 2013 |
| Evidence for orexinergic mechanisms in migraine J Hoffmann, W Supronsinchai, S Akerman, AP Andreou, CJ Winrow, ... Neurobiology of disease 74, 137-143, 2015 | 96 | 2015 |
| Crosstalk between the thyroid hormone and peroxisome proliferator-activated receptors in regulating peroxisome proliferator-responsive genes J Hunter, A Kassam, CJ Winrow, RA Rachubinski, JP Capone Molecular and cellular endocrinology 116 (2), 213-221, 1996 | 91 | 1996 |
