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Douglas C. Wu
Douglas C. Wu
Invitae
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Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression
Y Tan, A Tajik, J Chen, Q Jia, F Chowdhury, L Wang, J Chen, S Zhang, ...
Nature communications 5 (1), 4619, 2014
1882014
Dynamic force-induced direct dissociation of protein complexes in a nuclear body in living cells
YC Poh, SP Shevtsov, F Chowdhury, DC Wu, S Na, M Dundr, N Wang
Nature communications 3 (1), 866, 2012
1592012
Generation of organized germ layers from a single mouse embryonic stem cell
YC Poh, J Chen, Y Hong, H Yi, S Zhang, J Chen, DC Wu, L Wang, Q Jia, ...
Nature communications 5 (1), 4000, 2014
1492014
High-throughput sequencing of human plasma RNA by using thermostable group II intron reverse transcriptases
Y Qin, J Yao, DC Wu, RM Nottingham, S Mohr, S Hunicke-Smith, ...
RNA 22 (1), 111-128, 2016
1172016
Limitations of alignment-free tools in total RNA-seq quantification
DC Wu, J Yao, KS Ho, AM Lambowitz, CO Wilke
BMC genomics 19, 1-14, 2018
992018
RNA-seq of human reference RNA samples using a thermostable group II intron reverse transcriptase
RM Nottingham, DC Wu, Y Qin, J Yao, S Hunicke-Smith, AM Lambowitz
RNA 22 (4), 597-613, 2016
902016
Human airway cells prevent SARS-CoV-2 multibasic cleavage site cell culture adaptation
MM Lamers, AZ Mykytyn, TI Breugem, Y Wang, DC Wu, S Riesebosch, ...
Elife 10, e66815, 2021
882021
Preventing an antigenically disruptive mutation in egg-based H3N2 seasonal influenza vaccines by mutational incompatibility
NC Wu, H Lv, AJ Thompson, DC Wu, WWS Ng, RU Kadam, CW Lin, ...
Cell host & microbe 25 (6), 836-844. e5, 2019
732019
Improved TGIRT-seq methods for comprehensive transcriptome profiling with decreased adapter dimer formation and bias correction
H Xu, J Yao, DC Wu, AM Lambowitz
Scientific reports 9 (1), 7953, 2019
672019
Force via integrins but not E-cadherin decreases Oct3/4 expression in embryonic stem cells
Y Uda, YC Poh, F Chowdhury, DC Wu, TS Tanaka, M Sato, N Wang
Biochemical and biophysical research communications 415 (2), 396-400, 2011
452011
Facile single-stranded DNA sequencing of human plasma DNA via thermostable group II intron reverse transcriptase template switching
DC Wu, AM Lambowitz
Scientific reports 7 (1), 8421, 2017
282017
Identification of protein-protected mRNA fragments and structured excised intron RNAs in human plasma by TGIRT-seq peak calling
J Yao, DC Wu, RM Nottingham, AM Lambowitz
Elife 9, e60743, 2020
242020
Paramagnetic beads and magnetically mediated strain enhance cardiomyogenesis in mouse embryoid bodies
LR Geuss, DC Wu, D Ramamoorthy, CD Alford, LJ Suggs
PLoS One 9 (12), e113982, 2014
182014
Clinical correlations of transcriptional profile in patients infected with avian influenza H7N9 virus
W Guan, Z Yang, NC Wu, HHY Lee, Y Li, W Jiang, L Shen, DC Wu, ...
The Journal of Infectious Diseases 218 (8), 1238-1248, 2018
162018
Human organoid systems reveal in vitro correlates of fitness for SARS-CoV-2 B.1.1.7
MM Lamers, TI Breugem, AZ Mykytyn, Y Wang, N Groen, K Knoops, ...
BioRxiv, 2021.05. 03.441080, 2021
112021
Arg-tRNA synthetase links inflammatory metabolism to RNA splicing and nuclear trafficking via SRRM2
H Cui, JK Diedrich, DC Wu, JJ Lim, RM Nottingham, JJ Moresco, ...
Nature cell biology 25 (4), 592-603, 2023
82023
Contrasting roles of MERS-CoV and SARS-CoV-2 internal proteins in pathogenesis in mice
LYR Wong, A Odle, E Luhmann, DC Wu, Y Wang, QW Teo, C Ptak, ...
Mbio 14 (6), e02476-23, 2023
12023
Human cells contain myriad excised linear introns with potential functions in gene regulation and as RNA biomarkers
J Yao, H Xu, W Shelby, DC Wu, M Ares, AM Lambowitz
BioRxiv, 2021
12021
Publisher Correction: Arg-tRNA synthetase links inflammatory metabolism to RNA splicing and nuclear trafficking via SRRM2 (Nature Cell Biology,(2023), 25, 4,(592-603), 10.1038 …
H Cui, JK Diedrich, DC Wu, JJ Lim, RM Nottingham, JJ Moresco, JR Yates, ...
Nature cell biology 25 (7), 1073, 2023
2023
Arg-tRNA synthetase links inflammatory metabolism to RNA splicing via nuclear condensates
H Cui, JK Diedrich, DC Wu, JJ Lim, RM Nottingham, JJ Moresco, ...
bioRxiv, 2021.09. 07.459304, 2021
2021
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