Andrew F. Powers
Andrew F. Powers
University of California, Davis; University of Washington; Novartis, Ionis Pharmaceuticals
Verified email at
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Cited by
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo
WE Dowdle, B Nyfeler, J Nagel, RA Elling, S Liu, E Triantafellow, ...
Nature cell biology 16 (11), 1069-1079, 2014
Tension directly stabilizes reconstituted kinetochore-microtubule attachments
B Akiyoshi, KK Sarangapani, AF Powers, CR Nelson, SL Reichow, ...
Nature 468 (7323), 576-579, 2010
The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion
AF Powers, AD Franck, DR Gestaut, J Cooper, B Gracyzk, RR Wei, ...
Cell 136 (5), 865-875, 2009
The Dam1 kinetochore complex harnesses microtubule dynamics to produce force and movement
CL Asbury, DR Gestaut, AF Powers, AD Franck, TN Davis
Proceedings of the National Academy of Sciences 103 (26), 9873-9878, 2006
Inhibition of DYRK1A and GSK3B induces human β-cell proliferation
W Shen, B Taylor, Q Jin, V Nguyen-Tran, S Meeusen, YQ Zhang, ...
Nature communications 6 (1), 1-11, 2015
Tension applied through the Dam1 complex promotes microtubule elongation providing a direct mechanism for length control in mitosis
AD Franck, AF Powers, DR Gestaut, T Gonen, TN Davis, CL Asbury
Nature cell biology 9 (7), 832-837, 2007
Angiotensin II injures the arterial wall causing increased aortic stiffening in apolipoprotein E-deficient mice
DM Tham, B Martin-McNulty, YX Wang, V Da Cunha, DW Wilson, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2002
Synergistic effect of angiotensin II and nitric oxide synthase inhibitor in increasing aortic stiffness in mice
RM Fitch, JC Rutledge, YX Wang, AF Powers, JL Tseng, T Clary, ...
American Journal of Physiology-Heart and Circulatory Physiology 290 (3 …, 2006
Direct physical study of kinetochore–microtubule interactions by reconstitution and interrogation with an optical force clamp
AD Franck, AF Powers, DR Gestaut, TN Davis, CL Asbury
Methods 51 (2), 242-250, 2010
A novel and translational role for autophagy in antisense oligonucleotide trafficking and activity
J Ochaba, AF Powers, KA Tremble, S Greenlee, NM Post, JE Matson, ...
Nucleic acids research 47 (21), 11284-11303, 2019
Apolipoprotein E3-and Nitric Oxide–Dependent Modulation of Endothelial Cell Inflammatory Responses
AE Mullick, AF Powers, RS Kota, SD Tetali, JP Eiserich, JC Rutledge
Arteriosclerosis, thrombosis, and vascular biology 27 (2), 339-345, 2007
Hyperglycemia and loss of ovarian hormones mediate atheroma formation through endothelial layer disruption and increased permeability
J Benton, A Powers, L Eiselein, R Fitch, D Wilson, AC Villablanca, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2007
Measuring Kinetochore–Microtubule Interaction In Vitro
JW Driver, AF Powers, KK Sarangapani, S Biggins, CL Asbury
Methods in enzymology 540, 321-337, 2014
Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a …
E Pirie, S Ray, C Pan, W Fu, AF Powers, D Polikoff, CM Miller, KM Kudrna, ...
PLoS genetics 14 (10), e1007732, 2018
The Ndc80 kinetochore complex uses biased diffusion to couple chromosomes to dynamic microtubule tips
AF Powers, AD Franck, DR Gestaut, J Cooper, B Gracyzk, RR Wei, ...
Cell 136 (5), 865, 2009
OMA1 mediates local and global stress responses against protein misfolding in CHCHD10 mitochondrial myopathy
MK Shammas, X Huang, BP Wu, E Fessler, IY Song, NP Randolph, Y Li, ...
The Journal of Clinical Investigation 132 (14), 2022
2143-P: GLP-1 Conjugation Enhances the Activity of Antisense Oligonucleotides Targeting Islet Amyloid Polypeptide (IAPP) or Kelch-Like ECH Associated Protein 1 (Keap1) in …
W Fu, R Lee, EC Pirie, T Prakash, S Murray, AF Powers, RM Crooke
Diabetes 68 (Supplement_1), 2019
Prevention and regression of megamitochondria and steatosis by blocking mitochondrial fusion in the liver
T Yamada, D Murata, DE Kleiner, R Anders, AZ Rosenberg, J Kaplan, ...
Iscience 25 (4), 103996, 2022
Antisense Oligonucleotide-Mediated Silencing of Mitochondrial Fusion and Fission Factors Modulates Mitochondrial Dynamics and Rescues Mitochondrial Dysfunction
DA Garcia, AF Powers, TA Bell 3rd, S Guo, M Aghajan
Nucleic acid therapeutics 32 (1), 51-65, 2022
2066-P: Dyrk1a Antisense Oligonucleotides Conjugated to GLP-1R Agonist Promote Pancreatic Beta-Cell Proliferation
W Fu, R Lee, EC Pirie, T Prakash, S Murray, A Powers, AE Mullick, ...
Diabetes 69 (Supplement_1), 2020
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