Azacitidine and venetoclax in previously untreated acute myeloid leukemia CD DiNardo, BA Jonas, V Pullarkat, MJ Thirman, JS Garcia, AH Wei, ... New England Journal of Medicine 383 (7), 617-629, 2020 | 1828 | 2020 |
Telomerase activity in normal leukocytes and in hematologic malignancies CM Counter, J Gupta, CB Harley, B Leber, S Bacchetti | 1168 | 1995 |
Mitochondrio‐nuclear translocation of AIF in apoptosis and necrosis E Daugas, SA Susin, N Zamzami, KF Ferri, T Irinopoulou, N Larochette, ... The FASEB Journal 14 (5), 729-739, 2000 | 1066 | 2000 |
Mechanisms of action of Bcl-2 family proteins A Shamas-Din, J Kale, B Leber, DW Andrews Cold Spring Harbor perspectives in biology 5 (4), a008714, 2013 | 853 | 2013 |
Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax JF Lovell, LP Billen, S Bindner, A Shamas-Din, C Fradin, B Leber, ... Cell 135 (6), 1074-1084, 2008 | 692 | 2008 |
Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells E Sachlos, RM Risueño, S Laronde, Z Shapovalova, JH Lee, J Russell, ... Cell 149 (6), 1284-1297, 2012 | 563 | 2012 |
Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator C Brenner, H Cadiou, HLA Vieira, N Zamzami, I Marzo, Z Xie, B Leber, ... Oncogene 19 (3), 329-336, 2000 | 507 | 2000 |
BH3-only proteins: Orchestrators of apoptosis A Shamas-Din, H Brahmbhatt, B Leber, DW Andrews Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (4), 508-520, 2011 | 504 | 2011 |
Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis MG Annis, EL Soucie, PJ Dlugosz, JA Cruz‐Aguado, LZ Penn, B Leber, ... The EMBO journal 24 (12), 2096-2103, 2005 | 465 | 2005 |
Embedded together: the life and death consequences of interaction of the Bcl-2 family with membranes B Leber, J Lin, DW Andrews Apoptosis 12, 897-911, 2007 | 461 | 2007 |
Bcl‐2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types. W Zhu, A Cowie, GW Wasfy, LZ Penn, B Leber, DW Andrews The EMBO journal 15 (16), 4130-4141, 1996 | 429 | 1996 |
Bcl-XL inhibits membrane permeabilization by competing with Bax LP Billen, CL Kokoski, JF Lovell, B Leber, DW Andrews PLoS biology 6 (6), e147, 2008 | 378 | 2008 |
Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin S Assouline, B Culjkovic, E Cocolakis, C Rousseau, N Beslu, A Amri, ... Blood 114 (2), 257-260, 2009 | 337 | 2009 |
Bcl‐2 changes conformation to inhibit Bax oligomerization PJ Dlugosz, LP Billen, MG Annis, W Zhu, Z Zhang, J Lin, B Leber, ... The EMBO journal 25 (11), 2287-2296, 2006 | 330 | 2006 |
Long-term outcome of a pediatric-inspired regimen used for adults aged 18–50 years with newly diagnosed acute lymphoblastic leukemia DJ DeAngelo, KE Stevenson, SE Dahlberg, LB Silverman, S Couban, ... Leukemia 29 (3), 526-534, 2015 | 329 | 2015 |
Five new pedigrees with inherited RUNX1 mutations causing familial platelet disorder with propensity to myeloid malignancy CJ Owen, CL Toze, A Koochin, DL Forrest, CA Smith, JM Stevens, ... Blood, The Journal of the American Society of Hematology 112 (12), 4639-4645, 2008 | 276 | 2008 |
Campath-1H treatment of T-cell prolymphocytic leukemia in patients for whom at least one prior chemotherapy regimen has failed MJ Keating, B Cazin, S Coutre, R Birhiray, T Kovacsovics, W Langer, ... Journal of Clinical Oncology 20 (1), 205-213, 2002 | 241 | 2002 |
Interaction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosis JA Yethon, RF Epand, B Leber, RM Epand, DW Andrews Journal of Biological Chemistry 278 (49), 48935-48941, 2003 | 239 | 2003 |
Myc potentiates apoptosis by stimulating Bax activity at the mitochondria EL Soucie, MG Annis, J Sedivy, J Filmus, B Leber, DW Andrews, LZ Penn Molecular and cellular biology 21 (14), 4725-4736, 2001 | 204 | 2001 |
Still embedded together binding to membranes regulates Bcl-2 protein interactions B Leber, J Lin, DW Andrews Oncogene 29 (38), 5221-5230, 2010 | 201 | 2010 |