| Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape PP Shah, G Donahue, GL Otte, BC Capell, DM Nelson, K Cao, ... Genes & development 27 (16), 1787-1799, 2013 | 528 | 2013 |
| Lysosome-mediated processing of chromatin in senescence A Ivanov, J Pawlikowski, I Manoharan, J van Tuyn, DM Nelson, TS Rai, ... The Journal of cell biology 202 (1), 129-143, 2013 | 512 | 2013 |
| Cell cycle–regulated phosphorylation of p220NPAT by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription T Ma, BA Van Tine, Y Wei, MD Garrett, D Nelson, PD Adams, J Wang, ... Genes & development 14 (18), 2298-2313, 2000 | 421 | 2000 |
| Senescent cells harbour features of the cancer epigenome HA Cruickshanks, T McBryan, DM Nelson, ND VanderKraats, PP Shah, ... Nature cell biology 15 (12), 1495-1506, 2013 | 345 | 2013 |
| Defective S phase chromatin assembly causes DNA damage, activation of the S phase checkpoint, and S phase arrest X Ye, AA Franco, H Santos, DM Nelson, PD Kaufman, PD Adams Molecular cell 11 (2), 341-351, 2003 | 322 | 2003 |
| Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis AL Kennedy, JP Morton, I Manoharan, DM Nelson, NB Jamieson, ... Molecular cell 42 (1), 36-49, 2011 | 226 | 2011 |
| Coupling of DNA synthesis and histone synthesis in S phase independent of cyclin/cdk2 activity DM Nelson, X Ye, C Hall, H Santos, T Ma, GD Kao, TJ Yen, JW Harper, ... Molecular and cellular biology 22 (21), 7459-7472, 2002 | 216 | 2002 |
| HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia TS Rai, JJ Cole, DM Nelson, D Dikovskaya, WJ Faller, MG Vizioli, ... Genes & Development 28 (24), 2712-2725, 2014 | 148 | 2014 |
| HIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progression C Hall, DM Nelson, X Ye, K Baker, JA DeCaprio, S Seeholzer, M Lipinski, ... Molecular and cellular biology 21 (5), 1854-1865, 2001 | 147 | 2001 |
| Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2 CD Fisher, LM Augustine, JM Maher, DM Nelson, AL Slitt, CD Klaassen, ... Drug metabolism and disposition 35 (6), 995-1000, 2007 | 140 | 2007 |
| Evidence for the involvement of xenobiotic-responsive nuclear receptors in transcriptional effects upon perfluoroalkyl acid exposure in diverse species H Ren, B Vallanat, DM Nelson, LWY Yeung, KS Guruge, PKS Lam, ... Reproductive toxicology 27 (3-4), 266-277, 2009 | 103 | 2009 |
| A retrospective analysis of toxicogenomics in the safety assessment of drug candidates WR Foster, SJ Chen, A He, A Truong, V Bhaskaran, DM Nelson, ... Toxicologic pathology 35 (5), 621-635, 2007 | 96 | 2007 |
| Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and … DM Nelson, F Jaber-Hijazi, JJ Cole, NA Robertson, JS Pawlikowski, ... Genome biology 17 (1), 1-20, 2016 | 86 | 2016 |
| Critical Parameters for Efficient Sonication and Improved Chromatin Immunoprecipitation of High Molecular Weight Proteins NA Pchelintsev, PD Adams, DM Nelson PloS one 11 (1), e0148023, 2016 | 68 | 2016 |
| A comparison of oncogene-induced senescence and replicative senescence: implications for tumor suppression and aging DM Nelson, T McBryan, JC Jeyapalan, JM Sedivy, PD Adams Age 36 (3), 1049-1065, 2014 | 68 | 2014 |
| Senescence at a glance JS Pawlikowski, PD Adams, DM Nelson Journal of cell science 126 (18), 4061-4067, 2013 | 54 | 2013 |
| Critical role of kinase activity of hematopoietic progenitor kinase 1 in anti-tumor immune surveillance J Liu, J Curtin, D You, S Hillerman, B Li-Wang, R Eraslan, J Xie, ... PloS one 14 (3), e0212670, 2019 | 44 | 2019 |
| Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys H Shen, DM Nelson, RV Oliveira, Y Zhang, CA Mcnaney, X Gu, W Chen, ... Drug Metabolism and Disposition 46 (2), 178-188, 2018 | 43 | 2018 |
| Oncogene-Expressing Senescent Melanocytes Up-Regulate MHC Class II, a Candidate Melanoma Suppressor Function J van Tuyn, F Jaber-Hijazi, D MacKenzie, JJ Cole, E Mann, ... Journal of Investigative Dermatology 137 (10), 2197-2207, 2017 | 43 | 2017 |
| Coagulation-dependent gene expression and liver injury in rats given lipopolysaccharide with ranitidine but not with famotidine JP Luyendyk, LD Lehman-McKeeman, DM Nelson, VM Bhaskaran, ... Journal of Pharmacology and Experimental Therapeutics 317 (2), 635-643, 2006 | 32 | 2006 |
