paul klenerman
paul klenerman
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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
CL Day, DE Kaufmann, P Kiepiela, JA Brown, ES Moodley, S Reddy, ...
Nature 443 (7109), 350-354, 2006
Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections
V Appay, PR Dunbar, M Callan, P Klenerman, GMA Gillespie, L Papagno, ...
Nature medicine 8 (4), 379-385, 2002
Analysis of successful immune responses in persons infected with hepatitis C virus
F Lechner, DKH Wong, PR Dunbar, R Chapman, RT Chung, ...
The Journal of experimental medicine 191 (9), 1499-1512, 2000
Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA
P Kiepiela, AJ Leslie, I Honeyborne, D Ramduth, C Thobakgale, S Chetty, ...
Nature 432 (7018), 769-775, 2004
Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection
DA Price, PJR Goulder, P Klenerman, AK Sewell, PJ Easterbrook, ...
Proceedings of the National Academy of Sciences 94 (5), 1890-1895, 1997
Science forum: the human cell atlas
A Regev, SA Teichmann, ES Lander, I Amit, C Benoist, E Birney, ...
Elife 6, e27041, 2017
Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus
NH Gruener, F Lechner, MC Jung, H Diepolder, T Gerlach, G Lauer, ...
Journal of virology 75 (12), 5550-5558, 2001
Genome-wide genetic association of complex traits in heterogeneous stock mice
W Valdar, LC Solberg, D Gauguier, S Burnett, P Klenerman, WO Cookson, ...
Nature genetics 38 (8), 879-887, 2006
Immune surveillance against a solid tumor fails because of immunological ignorance
AF Ochsenbein, P Klenerman, U Karrer, B Ludewig, M Pericin, ...
Proceedings of the National Academy of Sciences 96 (5), 2233-2238, 1999
Guidelines for the use of flow cytometry and cell sorting in immunological studies
A Cossarizza, HD Chang, A Radbruch, M Akdis, I Andrä, F Annunziato, ...
European journal of immunology 47 (10), 1584-1797, 2017
Adaptation of HIV-1 to human leukocyte antigen class I
Y Kawashima, K Pfafferott, J Frater, P Matthews, R Payne, M Addo, ...
Nature 458 (7238), 641-645, 2009
Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants
P Klenerman, S Rowland-Jones, S McAdam, J Edwards, S Daenke, ...
Nature 369 (6479), 403-407, 1994
Direct ex vivo analysis of antigen-specific IFN-γ-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect …
AA Pathan, KA Wilkinson, P Klenerman, H McShane, RN Davidson, ...
The Journal of Immunology 167 (9), 5217-5225, 2001
Memory inflation: continuous accumulation of antiviral CD8+ T cells over time
U Karrer, S Sierro, M Wagner, A Oxenius, H Hengel, UH Koszinowski, ...
The Journal of Immunology 170 (4), 2022-2029, 2003
T cells and viral persistence: lessons from diverse infections
P Klenerman, A Hill
Nature immunology 6 (9), 873-879, 2005
Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man
E Barnes, A Folgori, S Capone, L Swadling, S Aston, A Kurioka, J Meyer, ...
Science translational medicine 4 (115), 115ra1-115ra1, 2012
Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes
P Klenerman, RM Zinkernagel
Nature 394 (6692), 482-485, 1998
CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained
F Lechner, NH Gruener, S Urbani, J Uggeri, T Santantonio, AR Kammer, ...
European journal of immunology 30 (9), 2479-2487, 2000
Antigenic oscillations and shifting immunodominance in HIV-1 infections
MA Nowak, RM May, RE Phillips, S Rowland-Jones, DG Lalloo, ...
Nature 375 (6532), 606-611, 1995
Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection
SM Rushbrook, SM Ward, E Unitt, SL Vowler, M Lucas, P Klenerman, ...
Journal of virology 79 (12), 7852-7859, 2005
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