Evidence that a single peptide–MHC complex on a target cell can elicit a cytolytic T cell response Y Sykulev, M Joo, I Vturina, TJ Tsomides, HN Eisen Immunity 4 (6), 565-571, 1996 | 856 | 1996 |
Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes Y Sykulev, A Brunmark, M Jackson, RJ Cohen, PA Peterson, HN Eisen Immunity 1 (1), 15-22, 1994 | 331 | 1994 |
High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins. Y Sykulev, A Brunmark, TJ TsoMIDES, S Kageyama, M Jackson, ... Proceedings of the National Academy of Sciences 91 (24), 11487-11491, 1994 | 254 | 1994 |
ICAM-1 co-stimulates target cells to facilitate antigen presentation T Lebedeva, ML Dustin, Y Sykulev Current opinion in immunology 17 (3), 251-258, 2005 | 236 | 2005 |
Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes N Anikeeva, K Somersalo, TN Sims, VK Thomas, ML Dustin, Y Sykulev Proceedings of the National Academy of Sciences 102 (18), 6437-6442, 2005 | 210 | 2005 |
Variations in the number of peptide-MHC class I complexes required to activate cytotoxic T cell responses. S Kageyama, TJ Tsomides, Y Sykulev, HN Eisen Journal of immunology (Baltimore, Md.: 1950) 154 (2), 567-576, 1995 | 190 | 1995 |
Cytotoxic T lymphocytes form an antigen-independent ring junction K Somersalo, N Anikeeva, TN Sims, VK Thomas, RK Strong, T Spies, ... The Journal of clinical investigation 113 (1), 49-57, 2004 | 149 | 2004 |
The law of mass action governs antigen-stimulated cytolytic activity of CD8+ cytotoxic T lymphocytes. Y Sykulev, RJ Cohen, HN Eisen Proceedings of the National Academy of Sciences 92 (26), 11990-11992, 1995 | 146 | 1995 |
Peptide antagonism and T cell receptor interactions with peptide-MHC complexes Y Sykulev, Y Vugmeyster, A Brunmark, HL Ploegh, HN Eisen Immunity 9 (4), 475-483, 1998 | 141 | 1998 |
Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain AM Beal, N Anikeeva, R Varma, TO Cameron, G Vasiliver-Shamis, ... Immunity 31 (4), 632-642, 2009 | 139 | 2009 |
Quantum dot/peptide-MHC biosensors reveal strong CD8-dependent cooperation between self and viral antigens that augment the T cell response N Anikeeva, T Lebedeva, AR Clapp, ER Goldman, ML Dustin, H Mattoussi, ... Proceedings of the National Academy of Sciences 103 (45), 16846-16851, 2006 | 125 | 2006 |
Multiple Effector Functions Mediated by Human Immunodeficiency Virus-Specific CD4+ T-Cell Clones PJ Norris, M Sumaroka, C Brander, HF Moffett, SL Boswell, T Nguyen, ... Journal of virology 75 (20), 9771-9779, 2001 | 99 | 2001 |
Antigen-specific T-cell receptors and their reactions with complexes formed by peptides with major histocompatibility complex proteins HN Eisen, Y Sykulev, TJ Tsomides Adv. Protein Chem 49, 1-56, 1996 | 89 | 1996 |
Protein kinase Cθ regulates stability of the peripheral adhesion ring junction and contributes to the sensitivity of target cell lysis by CTL AM Beal, N Anikeeva, R Varma, TO Cameron, PJ Norris, ML Dustin, ... The Journal of Immunology 181 (7), 4815-4824, 2008 | 76 | 2008 |
Differences in the level of expression of class I major histocompatibility complex proteins on thymic epithelial and dendritic cells influence the decision of immature … JR Delaney, Y Sykulev, HN Eisen, S Tonegawa Proceedings of the National Academy of Sciences 95 (9), 5235-5240, 1998 | 62 | 1998 |
Distinct molecular mechanisms account for the specificity of two different T-cell receptors N Anikeeva, T Lebedeva, M Krogsgaard, SY Tetin, E Martinez-Hackert, ... Biochemistry 42 (16), 4709-4716, 2003 | 61 | 2003 |
How a T cell receptor-like antibody recognizes major histocompatibility complex-bound peptide T Mareeva, E Martinez-Hackert, Y Sykulev Journal of biological chemistry 283 (43), 29053-29059, 2008 | 58 | 2008 |
Tpl2 and ERK transduce antiproliferative T cell receptor signals and inhibit transformation of chronically stimulated T cells C Tsatsanis, K Vaporidi, V Zacharioudaki, A Androulidaki, Y Sykulev, ... Proceedings of the National Academy of Sciences 105 (8), 2987-2992, 2008 | 48 | 2008 |
Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes N Anikeeva, Y Sykulev Immunologic research 51, 183-194, 2011 | 43 | 2011 |
Evidence that the density of self peptide-MHC ligands regulates T-cell receptor signaling N Anikeeva, D Gakamsky, J Schøller, Y Sykulev Public Library of Science 7 (8), e41466, 2012 | 41 | 2012 |