Alaa Othman
Alaa Othman
ETH Zürich ,Switzerland
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Plasma levels of sphingosine-1-phosphate and apolipoprotein M in patients with monogenic disorders of HDL metabolism
R Karuna, R Park, A Othman, AG Holleboom, MM Motazacker, I Sutter, ...
Atherosclerosis 219 (2), 855-863, 2011
Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control
DM Mueller, M Allenspach, A Othman, CH Saely, A Muendlein, ...
Atherosclerosis 243 (2), 638-644, 2015
Explaining ionic liquid water solubility in terms of cation and anion hydrophobicity
J Ranke, A Othman, P Fan, A Müller
International journal of molecular sciences 10 (3), 1271-1289, 2009
Plasma deoxysphingolipids: a novel class of biomarkers for the metabolic syndrome?
A Othman, MF Rütti, D Ernst, CH Saely, P Rein, H Drexel, ...
Diabetologia 55 (2), 421-431, 2012
Bile acid metabolites in serum: intraindividual variation and associations with coronary heart disease, metabolic syndrome and diabetes mellitus
C Steiner, A Othman, CH Saely, P Rein, H Drexel, A von Eckardstein, ...
PloS one 6 (11), e25006, 2011
Deoxysphingoid bases as plasma markers in diabetes mellitus
M Bertea, MF Rütti, A Othman, J Marti-Jaun, M Hersberger, ...
Lipids in health and disease 9 (1), 84, 2010
Deoxysphingolipids, novel biomarkers for type 2 diabetes, are cytotoxic for insulin-producing cells
RA Zuellig, T Hornemann, A Othman, AB Hehl, H Bode, T Güntert, ...
Diabetes 63 (4), 1326-1339, 2014
Plasmalogens of high-density lipoproteins (HDL) are associated with coronary artery disease and anti-apoptotic activity of HDL
I Sutter, S Velagapudi, A Othman, M Riwanto, J Manz, L Rohrer, ...
Atherosclerosis 241 (2), 539-546, 2015
Viral serine palmitoyltransferase induces metabolic switch in sphingolipid biosynthesis and is required for infection of a marine alga
C Ziv, S Malitsky, A Othman, S Ben-Dor, Y Wei, S Zheng, A Aharoni, ...
Proceedings of the National Academy of Sciences 113 (13), E1907-E1916, 2016
Lowering plasma 1-deoxysphingolipids improves neuropathy in diabetic rats
A Othman, R Bianchi, I Alecu, Y Wei, C Porretta-Serapiglia, R Lombardi, ...
Diabetes 64 (3), 1035-1045, 2015
Neurotoxic 1‐deoxysphingolipids and paclitaxel‐induced peripheral neuropathy
R Kramer, J Bielawski, E Kistner‐Griffin, A Othman, I Alecu, D Ernst, ...
The FASEB Journal 29 (11), 4461-4472, 2015
HSAN1 mutations in serine palmitoyltransferase reveal a close structure–function–phenotype relationship
H Bode, F Bourquin, S Suriyanarayanan, Y Wei, I Alecu, A Othman, ...
Human molecular genetics 25 (5), 853-865, 2016
Apolipoprotein M modulates erythrocyte efflux and tubular reabsorption of sphingosine-1-phosphate
I Sutter, R Park, A Othman, L Rohrer, T Hornemann, M Stoffel, O Devuyst, ...
Journal of lipid research 55 (8), 1730-1737, 2014
Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway
I Alecu, A Othman, A Penno, EM Saied, C Arenz, A von Eckardstein, ...
Journal of lipid research 58 (1), 60-71, 2017
Elucidating the chemical structure of native 1-deoxysphingosine
R Steiner, EM Saied, A Othman, C Arenz, AT Maccarone, BLJ Poad, ...
Journal of lipid research 57 (7), 1194-1203, 2016
Decreased phosphatidylcholine plasmalogens–A putative novel lipid signature in patients with stable coronary artery disease and acute myocardial infarction
I Sutter, R Klingenberg, A Othman, L Rohrer, U Landmesser, D Heg, ...
Atherosclerosis 246, 130-140, 2016
Plasma 1-deoxysphingolipids are early predictors of incident type 2 diabetes mellitus
J Mwinyi, A Boström, I Fehrer, A Othman, G Waeber, H Marti-Soler, ...
PloS one 12 (5), e0175776, 2017
Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction
I Alecu, A Tedeschi, N Behler, K Wunderling, C Lamberz, ...
Journal of lipid research 58 (1), 42-59, 2017
Elevation of plasma 1‐deoxy‐sphingolipids in type 2 diabetes mellitus: a susceptibility to neuropathy?
MF Dohrn, A Othman, SK Hirshman, H Bode, I Alecu, E Fähndrich, ...
European journal of neurology 22 (5), 806-e55, 2015
Plasma 1-deoxysphingolipids are predictive biomarkers for type 2 diabetes mellitus
A Othman, CH Saely, A Muendlein, A Vonbank, H Drexel, ...
BMJ Open Diabetes Research and Care 3 (1), 2015
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