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Rana Soylu-Kucharz
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Mutant huntingtin causes metabolic imbalance by disruption of hypothalamic neurocircuits
S Hult, R Soylu, T Björklund, BF Belgardt, J Mauer, JC Brüning, D Kirik, ...
Cell metabolism 13 (4), 428-439, 2011
1202011
Hypothalamic expression of mutant huntingtin contributes to the development of depressive-like behavior in the BAC transgenic mouse model of Huntington's disease
S Hult Lundh, N Nilsson, R Soylu, D Kirik, Å Petersén
Human molecular genetics 22 (17), 3485-3497, 2013
812013
Human α-synuclein overexpression in a mouse model of Parkinson’s disease leads to vascular pathology, blood brain barrier leakage and pericyte activation
O Elabi, A Gaceb, R Carlsson, T Padel, R Soylu-Kucharz, I Cortijo, W Li, ...
Scientific reports 11 (1), 1120, 2021
782021
Increased intestinal permeability and gut dysbiosis in the R6/2 mouse model of Huntington’s disease
TL Stan, R Soylu-Kucharz, S Burleigh, O Prykhodko, L Cao, N Franke, ...
Scientific reports 10 (1), 18270, 2020
692020
A point mutation in the dynein heavy chain gene leads to striatal atrophy and compromises neurite outgrowth of striatal neurons
KE Braunstein, J Eschbach, K Ròna-Vörös, R Soylu, E Mikrouli, Y Larmet, ...
Human molecular genetics 19 (22), 4385-4398, 2010
692010
Increased numbers of orexin/hypocretin neurons in a genetic rat depression model
E Mikrouli, G Wörtwein, R Soylu, AA Mathé, Å Petersén
Neuropeptides 45 (6), 401-406, 2011
622011
Neurofilament light protein in CSF and blood is associated with neurodegeneration and disease severity in Huntington’s disease R6/2 mice
R Soylu-Kucharz, Å Sandelius, M Sjögren, K Blennow, EJ Wild, ...
Scientific reports 7 (1), 14114, 2017
582017
Apolipoprotein M-bound sphingosine-1-phosphate regulates blood–brain barrier paracellular permeability and transcytosis
M Mathiesen Janiurek, R Soylu-Kucharz, C Christoffersen, K Kucharz, ...
Elife 8, e49405, 2019
572019
Hypothalamic and neuroendocrine changes in Huntington's disease
S Hult, K Schultz, R Soylu, A Petersen
Current drug targets 11 (10), 1237-1249, 2010
512010
SIRT1 is increased in affected brain regions and hypothalamic metabolic pathways are altered in Huntington disease
B Baldo, S Gabery, R Soylu‐Kucharz, RY Cheong, JB Henningsen, ...
Neuropathology and applied neurobiology 45 (4), 361-379, 2019
332019
Maintenance of basal levels of autophagy in Huntington’s disease mouse models displaying metabolic dysfunction
B Baldo, R Soylu, Å Petersén
PloS one 8 (12), e83050, 2013
282013
Expression of mutant huntingtin in leptin receptor-expressing neurons does not control the metabolic and psychiatric phenotype of the BACHD mouse
SH Lundh, R Soylu, Å Petersén
PloS one 7 (12), e51168, 2012
262012
Low dietary protein content alleviates motor symptoms in mice with mutant dynactin/dynein-mediated neurodegeneration
D Wiesner, J Sinniger, A Henriques, S Dieterlé, HP Müller, V Rasche, ...
Human molecular genetics 24 (8), 2228-2240, 2015
212015
Metabolic and behavioral effects of mutant huntingtin deletion in Sim1 neurons in the BACHD mouse model of Huntington’s disease
R Soylu-Kucharz, B Baldo, Å Petersén
Scientific reports 6 (1), 28322, 2016
192016
Hypothalamic overexpression of mutant huntingtin causes dysregulation of brown adipose tissue
R Soylu-Kucharz, N Adlesic, B Baldo, D Kirik, Å Petersén
Scientific reports 5 (1), 14598, 2015
162015
Characterization of a rat model of Huntington’s disease based on targeted expression of mutant huntingtin in the forebrain using adeno‐associated viral vectors
S Gabery, MU Sajjad, S Hult, R Soylu, D Kirik, Å Petersén
European Journal of Neuroscience 36 (6), 2789-2800, 2012
162012
Leptin deficiency reverses high metabolic state and weight loss without affecting central pathology in the R6/2 mouse model of Huntington's disease
M Sjögren, R Soylu-Kucharz, U Dandunna, TL Stan, M Cavalera, ...
Neurobiology of disease 132, 104560, 2019
152019
Hypothalamic expression of huntingtin causes distinct metabolic changes in Huntington's disease mice
E Dickson, R Soylu-Kucharz, Å Petersén, M Björkqvist
Molecular Metabolism 57, 101439, 2022
122022
Preserved blood-brain barrier and neurovascular coupling in female 5xFAD model of Alzheimer’s disease
O Zhukov, C He, R Soylu-Kucharz, C Cai, AD Lauritzen, BI Aldana, ...
Frontiers in Aging Neuroscience 15, 1089005, 2023
72023
Microarray profiling of hypothalamic gene expression changes in Huntington’s disease mouse models
E Dickson, AS Dwijesha, N Andersson, S Lundh, M Björkqvist, Å Petersén, ...
Frontiers in Neuroscience 16, 1027269, 2022
42022
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