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Sam Molyneux
Sam Molyneux
Verified email at uhnres.utoronto.ca
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Year
Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression
IS Harris, AE Treloar, S Inoue, M Sasaki, C Gorrini, KC Lee, KY Yung, ...
Cancer cell 27 (2), 211-222, 2015
9022015
BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival
C Gorrini, PS Baniasadi, IS Harris, J Silvester, S Inoue, B Snow, PA Joshi, ...
Journal of Experimental Medicine 210 (8), 1529-1544, 2013
3002013
A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis
BS Moriarity, GM Otto, EP Rahrmann, SK Rathe, NK Wolf, MT Weg, ...
Nature genetics 47 (6), 615-624, 2015
2552015
Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state
M Shimoda, S Principe, HW Jackson, V Luga, H Fang, SD Molyneux, ...
Nature cell biology 16 (9), 889-901, 2014
2112014
Estrogen controls the survival of BRCA1-deficient cells via a PI3K–NRF2-regulated pathway
C Gorrini, BP Gang, C Bassi, A Wakeham, SP Baniasadi, Z Hao, WY Li, ...
Proceedings of the National Academy of Sciences 111 (12), 4472-4477, 2014
1362014
Notch activation by the metalloproteinase ADAM17 regulates myeloproliferation and atopic barrier immunity by suppressing epithelial cytokine synthesis
A Murthy, YW Shao, SR Narala, SD Molyneux, JC Zúñiga-Pflücker, ...
Immunity 36 (1), 105-119, 2012
1252012
Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice
SD Molyneux, MA Di Grappa, AG Beristain, TD McKee, DH Wai, ...
The Journal of clinical investigation 120 (9), 3310-3325, 2010
1092010
PKA signaling drives mammary tumorigenesis through Src
AG Beristain, SD Molyneux, PA Joshi, NC Pomroy, MA Di Grappa, ...
Oncogene 34 (9), 1160-1173, 2015
962015
RANKL blockade prevents and treats aggressive osteosarcomas
Y Chen, MA Di Grappa, SD Molyneux, TD McKee, P Waterhouse, ...
Science translational medicine 7 (317), 317ra197-317ra197, 2015
822015
Cross-species genomics identifies DLG2 as a tumor suppressor in osteosarcoma
YW Shao, GA Wood, J Lu, QL Tang, J Liu, S Molyneux, Y Chen, H Fang, ...
Oncogene 38 (2), 291-298, 2019
762019
Human somatic cell mutagenesis creates genetically tractable sarcomas
SD Molyneux, PD Waterhouse, D Shelton, YW Shao, CM Watling, ...
Nature genetics 46 (9), 964-972, 2014
352014
Author Correction: Human somatic cell mutagenesis creates genetically tractable sarcomas
SD Molyneux, PD Waterhouse, D Shelton, YW Shao, CM Watling, ...
Nature genetics 52 (4), 464, 2020
2020
Genome-wide comparison of matched canine osteosarcoma primary tumours and metastases by array comparative genomic hybridization.
JHW Liu, YW Shao, SD Molyneux, R Khokha, GA Wood
Cancer Research 73 (8_Supplement), 398-398, 2013
2013
Abstract A6: Dissecting mechanisms of RANKL dependency in osteosarcoma
AG Beristain, S Molyneux, MA Di Grappa, R Khokha
Cancer Research 69 (23_Supplement), A6-A6, 2009
2009
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