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Lukas Heger
Lukas Heger
Laboratory of DC Biology, University Hospital Erlangen
Bestätigte E-Mail-Adresse bei uk-erlangen.de
Titel
Zitiert von
Zitiert von
Jahr
Human lymphoid organ dendritic cell identity is predominantly dictated by ontogeny, not tissue microenvironment
GF Heidkamp, J Sander, CHK Lehmann, L Heger, N Eissing, A Baranska, ...
Science immunology 1 (6), eaai7677, 2016
1402016
CLEC10A Is a Specific Marker for Human CD1c+ Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion
L Heger, S Balk, JJ Lühr, GF Heidkamp, CHK Lehmann, L Hatscher, ...
Frontiers in immunology 9, 744, 2018
1092018
Direct delivery of antigens to dendritic cells via antibodies specific for endocytic receptors as a promising strategy for future therapies
CHK Lehmann, L Heger, GF Heidkamp, A Baranska, JJ Lühr, A Hoffmann, ...
Vaccines 4 (2), 8, 2016
962016
Antigen delivery to CD11c+ CD8− dendritic cells induces protective immune responses against experimental melanoma in mice in vivo
K Neubert, CHK Lehmann, L Heger, A Baranska, AM Staedtler, ...
The Journal of Immunology 192 (12), 5830-5838, 2014
742014
DC subset–specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo
CHK Lehmann, A Baranska, GF Heidkamp, L Heger, K Neubert, JJ Lühr, ...
Journal of Experimental Medicine 214 (5), 1509-1528, 2017
622017
Transcriptional control of dendritic cell development and functions
L Amon, CHK Lehmann, A Baranska, J Schoen, L Heger, D Dudziak
International Review of Cell and Molecular Biology 349, 55-151, 2019
602019
Subsets of CD1c+ DCs: Dendritic Cell Versus Monocyte Lineage
L Heger, TP Hofer, V Bigley, IJM de Vries, M Dalod, D Dudziak, ...
Frontiers in Immunology 11, 559166, 2020
462020
Mutations in the B. 1.1. 7 SARS-CoV-2 spike protein reduce receptor-binding affinity and induce a flexible link to the fusion peptide
E Socher, M Conrad, L Heger, F Paulsen, H Sticht, F Zunke, P Arnold
Biomedicines 9 (5), 525, 2021
392021
Select hyperactivating NLRP3 ligands enhance the TH1- and TH17-inducing potential of human type 2 conventional dendritic cells
L Hatscher, CHK Lehmann, A Purbojo, C Onderka, C Liang, A Hartmann, ...
Science Signaling 14 (680), eabe1757, 2021
392021
Maturation of monocyte-derived DCs leads to increased cellular stiffness, higher membrane fluidity, and changed lipid composition
JJ Lühr, N Alex, L Amon, M Kräter, M Kubánková, E Sezgin, ...
Frontiers in immunology 11, 590121, 2020
362020
Molecular dynamics simulations of the delta and omicron SARS-CoV-2 spike–ACE2 complexes reveal distinct changes between both variants
E Socher, L Heger, F Paulsen, F Zunke, P Arnold
Computational and structural biotechnology journal 20, 1168-1176, 2022
352022
The ontogenetic path of human dendritic cells
L Amon, CHK Lehmann, L Heger, GF Heidkamp, D Dudziak
Molecular immunology 120, 122-129, 2020
342020
Melanocytes as emerging key players in niche regulation of limbal epithelial stem cells
N Polisetti, A Giessl, M Zenkel, L Heger, D Dudziak, E Naschberger, ...
The Ocular Surface 22, 172-189, 2021
312021
Impaired gp100-Specific CD8+ T-cell responses in the presence of myeloid-derived suppressor cells in a spontaneous mouse melanoma model
DG Mairhofer, D Ortner, CH Tripp, S Schaffenrath, V Fleming, L Heger, ...
Journal of Investigative Dermatology 135 (11), 2785-2793, 2015
272015
Harnessing the complete repertoire of conventional dendritic cell functions for cancer immunotherapy
L Amon, L Hatscher, L Heger, D Dudziak, CHK Lehmann
Pharmaceutics 12 (7), 663, 2020
252020
Inflammasomes in dendritic cells: Friend or foe?
L Hatscher, L Amon, L Heger, D Dudziak
Immunology Letters 234, 16-32, 2021
232021
Monocyte-Derived Signals Activate Human Natural Killer Cells in Response to Leishmania Parasites
H Messlinger, H Sebald, L Heger, D Dudziak, C Bogdan, U Schleicher
Frontiers in immunology 9, 24, 2018
222018
Easy performance of 6-color confocal immunofluorescence with 4-laser line microscopes
N Eissing, L Heger, A Baranska, R Cesnjevar, M Büttner-Herold, S Söder, ...
Immunology letters 161 (1), 1-5, 2014
202014
Loading of primary human T Lymphocytes with citrate-coated superparamagnetic iron oxide nanoparticles does not impair their activation after polyclonal stimulation
M Mühlberger, H Unterweger, J Band, C Lehmann, L Heger, D Dudziak, ...
Cells 9 (2), 342, 2020
182020
Computational decomposition reveals reshaping of the SARS‐CoV‐2–ACE2 interface among viral variants expressing the N501Y mutation
E Socher, M Conrad, L Heger, F Paulsen, H Sticht, F Zunke, P Arnold
Journal of cellular biochemistry 122 (12), 1863-1872, 2021
162021
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