Human lymphoid organ dendritic cell identity is predominantly dictated by ontogeny, not tissue microenvironment GF Heidkamp, J Sander, CHK Lehmann, L Heger, N Eissing, A Baranska, ... Science immunology 1 (6), eaai7677, 2016 | 140 | 2016 |
CLEC10A Is a Specific Marker for Human CD1c+ Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion L Heger, S Balk, JJ Lühr, GF Heidkamp, CHK Lehmann, L Hatscher, ... Frontiers in immunology 9, 744, 2018 | 109 | 2018 |
Direct delivery of antigens to dendritic cells via antibodies specific for endocytic receptors as a promising strategy for future therapies CHK Lehmann, L Heger, GF Heidkamp, A Baranska, JJ Lühr, A Hoffmann, ... Vaccines 4 (2), 8, 2016 | 96 | 2016 |
Antigen delivery to CD11c+ CD8− dendritic cells induces protective immune responses against experimental melanoma in mice in vivo K Neubert, CHK Lehmann, L Heger, A Baranska, AM Staedtler, ... The Journal of Immunology 192 (12), 5830-5838, 2014 | 74 | 2014 |
DC subset–specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo CHK Lehmann, A Baranska, GF Heidkamp, L Heger, K Neubert, JJ Lühr, ... Journal of Experimental Medicine 214 (5), 1509-1528, 2017 | 62 | 2017 |
Transcriptional control of dendritic cell development and functions L Amon, CHK Lehmann, A Baranska, J Schoen, L Heger, D Dudziak International Review of Cell and Molecular Biology 349, 55-151, 2019 | 60 | 2019 |
Subsets of CD1c+ DCs: Dendritic Cell Versus Monocyte Lineage L Heger, TP Hofer, V Bigley, IJM de Vries, M Dalod, D Dudziak, ... Frontiers in Immunology 11, 559166, 2020 | 46 | 2020 |
Mutations in the B. 1.1. 7 SARS-CoV-2 spike protein reduce receptor-binding affinity and induce a flexible link to the fusion peptide E Socher, M Conrad, L Heger, F Paulsen, H Sticht, F Zunke, P Arnold Biomedicines 9 (5), 525, 2021 | 39 | 2021 |
Select hyperactivating NLRP3 ligands enhance the TH1- and TH17-inducing potential of human type 2 conventional dendritic cells L Hatscher, CHK Lehmann, A Purbojo, C Onderka, C Liang, A Hartmann, ... Science Signaling 14 (680), eabe1757, 2021 | 39 | 2021 |
Maturation of monocyte-derived DCs leads to increased cellular stiffness, higher membrane fluidity, and changed lipid composition JJ Lühr, N Alex, L Amon, M Kräter, M Kubánková, E Sezgin, ... Frontiers in immunology 11, 590121, 2020 | 36 | 2020 |
Molecular dynamics simulations of the delta and omicron SARS-CoV-2 spike–ACE2 complexes reveal distinct changes between both variants E Socher, L Heger, F Paulsen, F Zunke, P Arnold Computational and structural biotechnology journal 20, 1168-1176, 2022 | 35 | 2022 |
The ontogenetic path of human dendritic cells L Amon, CHK Lehmann, L Heger, GF Heidkamp, D Dudziak Molecular immunology 120, 122-129, 2020 | 34 | 2020 |
Melanocytes as emerging key players in niche regulation of limbal epithelial stem cells N Polisetti, A Giessl, M Zenkel, L Heger, D Dudziak, E Naschberger, ... The Ocular Surface 22, 172-189, 2021 | 31 | 2021 |
Impaired gp100-Specific CD8+ T-cell responses in the presence of myeloid-derived suppressor cells in a spontaneous mouse melanoma model DG Mairhofer, D Ortner, CH Tripp, S Schaffenrath, V Fleming, L Heger, ... Journal of Investigative Dermatology 135 (11), 2785-2793, 2015 | 27 | 2015 |
Harnessing the complete repertoire of conventional dendritic cell functions for cancer immunotherapy L Amon, L Hatscher, L Heger, D Dudziak, CHK Lehmann Pharmaceutics 12 (7), 663, 2020 | 25 | 2020 |
Inflammasomes in dendritic cells: Friend or foe? L Hatscher, L Amon, L Heger, D Dudziak Immunology Letters 234, 16-32, 2021 | 23 | 2021 |
Monocyte-Derived Signals Activate Human Natural Killer Cells in Response to Leishmania Parasites H Messlinger, H Sebald, L Heger, D Dudziak, C Bogdan, U Schleicher Frontiers in immunology 9, 24, 2018 | 22 | 2018 |
Easy performance of 6-color confocal immunofluorescence with 4-laser line microscopes N Eissing, L Heger, A Baranska, R Cesnjevar, M Büttner-Herold, S Söder, ... Immunology letters 161 (1), 1-5, 2014 | 20 | 2014 |
Loading of primary human T Lymphocytes with citrate-coated superparamagnetic iron oxide nanoparticles does not impair their activation after polyclonal stimulation M Mühlberger, H Unterweger, J Band, C Lehmann, L Heger, D Dudziak, ... Cells 9 (2), 342, 2020 | 18 | 2020 |
Computational decomposition reveals reshaping of the SARS‐CoV‐2–ACE2 interface among viral variants expressing the N501Y mutation E Socher, M Conrad, L Heger, F Paulsen, H Sticht, F Zunke, P Arnold Journal of cellular biochemistry 122 (12), 1863-1872, 2021 | 16 | 2021 |