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Juerg Schwaller
Juerg Schwaller
Bestätigte E-Mail-Adresse bei unibas.ch
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Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice
R Tiedt, H Hao-Shen, MA Sobas, R Looser, S Dirnhofer, J Schwaller, ...
Blood, The Journal of the American Society of Hematology 111 (8), 3931-3940, 2008
5252008
Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms
L Arranz, A Sánchez-Aguilera, D Martín-Pérez, J Isern, X Langa, ...
Nature 512 (7512), 78-81, 2014
4672014
PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers
L Brault, C Gasser, F Bracher, K Huber, S Knapp, J Schwaller
haematologica 95 (6), 1004-1015, 2010
4172010
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases
O Fedorov, B Marsden, V Pogacic, P Rellos, S Müller, AN Bullock, ...
Proceedings of the National Academy of Sciences 104 (51), 20523-20528, 2007
4122007
Stat5 is essential for the myelo-and lymphoproliferative disease induced by TEL/JAK2
J Schwaller, E Parganas, D Wang, D Cain, JC Aster, IR Williams, CK Lee, ...
Molecular cell 6 (3), 693-704, 2000
3762000
Programmed death 1 signaling on chronic myeloid leukemia–specific T cells results in T-cell exhaustion and disease progression
S Mumprecht, C Schürch, J Schwaller, M Solenthaler, AF Ochsenbein
Blood, The Journal of the American Society of Hematology 114 (8), 1528-1536, 2009
3322009
Transformation of hematopoietic cell lines to growth‐factor independence and induction of a fatal myelo‐and lymphoproliferative disease in mice by retrovirally transduced TEL …
J Schwaller, J Frantsve, J Aster, IR Williams, MH Tomasson, TS Ross, ...
The EMBO journal 17 (18), 5321-5333, 1998
3231998
Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion
AM Paczulla, K Rothfelder, S Raffel, M Konantz, J Steinbacher, H Wang, ...
Nature 572 (7768), 254-259, 2019
2992019
PFI-1, a highly selective protein interaction inhibitor, targeting BET Bromodomains
S Picaud, D Da Costa, A Thanasopoulou, P Filippakopoulos, PV Fish, ...
Cancer research 73 (11), 3336-3346, 2013
2882013
Generation of a selective small molecule inhibitor of the CBP/p300 bromodomain for leukemia therapy
S Picaud, O Fedorov, A Thanasopoulou, K Leonards, K Jones, J Meier, ...
Cancer research 75 (23), 5106-5119, 2015
2392015
Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation
J Frantsve, J Schwaller, DW Sternberg, J Kutok, DG Gilliland
Molecular and cellular biology 21 (10), 3547-3557, 2001
2362001
Structural analysis identifies imidazo [1, 2-b] pyridazines as PIM kinase inhibitors with in vitro antileukemic activity
V Pogacic, AN Bullock, O Fedorov, P Filippakopoulos, C Gasser, A Biondi, ...
Cancer research 67 (14), 6916-6924, 2007
2272007
MLL-AF9 expression in hematopoietic stem cells drives a highly invasive AML expressing EMT-related genes linked to poor outcome
V Stavropoulou, S Kaspar, L Brault, MA Sanders, S Juge, S Morettini, ...
Cancer cell 30 (1), 43-58, 2016
2142016
Analysis of a family of cyclin-dependent kinase inhibitors: p15/MTS2/INK4B, p16/MTS1/INK4A, and p18 genes in acute lymphoblastic leukemia of childhood
S Takeuchi, CR Bartram, T Seriu, CW Miller, A Tobler, JW Janssen, ...
2041995
Dissection of PIM serine/threonine kinases in FLT3-ITD–induced leukemogenesis reveals PIM1 as regulator of CXCL12–CXCR4-mediated homing and migration
R Grundler, L Brault, C Gasser, AN Bullock, T Dechow, S Woetzel, ...
Journal of experimental medicine 206 (9), 1957-1970, 2009
1752009
Neutrophil-derived APRIL concentrated in tumor lesions by proteoglycans correlates with human B-cell lymphoma aggressiveness
J Schwaller, P Schneider, P Mhawech-Fauceglia, T McKee, S Myit, ...
Blood 109 (1), 331-338, 2007
1742007
The expression of ETV6/CBFA2 (TEL/AML1) is not sufficient for the transformation of hematopoietic cell lines in vitro or the induction of hematologic disease in vivo
P Andreasson, J Schwaller, E Anastasiadou, J Aster, DG Gilliland
Cancer genetics and cytogenetics 130 (2), 93-104, 2001
1632001
Bone marrow mesenchymal stem cells support acute myeloid leukemia bioenergetics and enhance antioxidant defense and escape from chemotherapy
D Forte, M García-Fernández, A Sánchez-Aguilera, V Stavropoulou, ...
Cell metabolism 32 (5), 829-843. e9, 2020
1462020
Posttranscriptional stabilization underlies p53-independent induction of p21WAF1/CIP1/SDI1 in differentiating human leukemic cells.
J Schwaller, HP Koeffler, G Niklaus, P Loetscher, S Nagel, MF Fey, ...
The Journal of clinical investigation 95 (3), 973-979, 1995
1421995
H4(D10S170), a gene frequently rearranged in papillary thyroid carcinoma, is fused to the platelet-derived growth factor receptor β gene in atypical chronic myeloid …
J Schwaller, E Anastasiadou, D Cain, J Kutok, S Wojiski, IR Williams, ...
Blood, The Journal of the American Society of Hematology 97 (12), 3910-3918, 2001
1412001
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