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Simon Currie
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Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs
Y Lin, SL Currie, MK Rosen
Journal of Biological Chemistry 292 (46), 19110-19120, 2017
3272017
Synergy of aromatic residues and phosphoserines within the intrinsically disordered DNA-binding inhibitory elements of the Ets-1 transcription factor
G Desjardins, CA Meeker, N Bhachech, SL Currie, M Okon, BJ Graves, ...
Proceedings of the National Academy of Sciences 111 (30), 11019-11024, 2014
472014
ETV4 and AP1 transcription factors form multivalent interactions with three sites on the MED25 activator-interacting domain
SL Currie, JJ Doane, KS Evans, N Bhachech, BJ Madison, DKW Lau, ...
Journal of molecular biology 429 (20), 2975-2995, 2017
432017
Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5
SL Currie, DKW Lau, JJ Doane, FG Whitby, M Okon, LP McIntosh, ...
Nucleic Acids Research 45 (5), 2223-2241, 2017
372017
Interaction of the Jhd2 histone H3 Lys-4 demethylase with chromatin is controlled by histone H2A surfaces and restricted by H2B ubiquitination
F Huang, S Ramakrishnan, S Pokhrel, C Pflueger, TJ Parnell, MM Kasten, ...
Journal of Biological Chemistry 290 (48), 28760-28777, 2015
212015
Electrostatic repulsion causes anticooperative DNA binding between tumor suppressor ETS transcription factors and JUN–FOS at composite DNA sites
BJ Madison, KA Clark, N Bhachech, PC Hollenhorst, BJ Graves, SL Currie
Journal of Biological Chemistry 293 (48), 18624-18635, 2018
182018
Quantitative reconstitution of yeast RNA processing bodies
SL Currie, W Xing, D Muhlrad, CJ Decker, R Parker, MK Rosen
Proceedings of the National Academy of Sciences 120 (14), e2214064120, 2023
172023
Using quantitative reconstitution to investigate multicomponent condensates
SL Currie, MK Rosen
Rna 28 (1), 27-35, 2022
162022
Development of high-throughput screening assays for inhibitors of ETS transcription factors
SL Currie, SL Warner, H Vankayalapati, X Liu, S Sharma, DJ Bearss, ...
SLAS DISCOVERY: Advancing Life Sciences R&D 24 (1), 77-85, 2019
22019
Depicting a cellular space occupied by condensates
D Liu, M Riggi, HO Lee, SL Currie, DS Goodsell, JH Iwasa, O Rog
Molecular biology of the cell 34 (10), tp2, 2023
12023
Molecular features driving condensate formation and gene expression by the BRD4-NUT fusion oncoprotein are overlapping but distinct
M Kosno, SL Currie, A Kumar, C Xing, MK Rosen
Scientific reports 13 (1), 11907, 2023
2023
The structural and biochemical characterization of ETS transcription factors with relevance to prostate cancer
SL Currie
The University of Utah, 2016
2016
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Articles 1–12