| Mechanisms and regulation of cholesterol homeostasis J Luo, H Yang, BL Song Nature reviews Molecular cell biology 21 (4), 225-245, 2020 | 1184 | 2020 |
| Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism W Yang, Y Bai, Y Xiong, J Zhang, S Chen, X Zheng, X Meng, L Li, J Wang, ... Nature 531 (7596), 651-655, 2016 | 755 | 2016 |
| Cholesterol metabolism in cancer: mechanisms and therapeutic opportunities B Huang, B Song, C Xu Nature metabolism 2 (2), 132-141, 2020 | 488 | 2020 |
| Inhibition of SREBP by a small molecule, betulin, improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques JJ Tang, JG Li, W Qi, WW Qiu, PS Li, BL Li, BL Song Cell metabolism 13 (1), 44-56, 2011 | 439 | 2011 |
| Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase BL Song, N Sever, RA DeBose-Boyd Molecular cell 19 (6), 829-840, 2005 | 423 | 2005 |
| The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1 L Ge, J Wang, W Qi, HH Miao, J Cao, YX Qu, BL Li, BL Song Cell metabolism 7 (6), 508-519, 2008 | 417 | 2008 |
| Cholesterol transport through lysosome-peroxisome membrane contacts BB Chu, YC Liao, W Qi, C Xie, X Du, J Wang, H Yang, HH Miao, BL Li, ... Cell 161 (2), 291-306, 2015 | 386 | 2015 |
| Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol N Sever, BL Song, D Yabe, JL Goldstein, MS Brown, RA DeBose-Boyd Journal of Biological Chemistry 278 (52), 52479-52490, 2003 | 374 | 2003 |
| Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol BL Song, NB Javitt, RA DeBose-Boyd Cell metabolism 1 (3), 179-189, 2005 | 326 | 2005 |
| The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity B Shan, X Wang, Y Wu, C Xu, Z Xia, J Dai, M Shao, F Zhao, S He, L Yang, ... Nature immunology 18 (5), 519-529, 2017 | 309 | 2017 |
| Cholesterol homeostatic regulator SCAP-SREBP2 integrates NLRP3 inflammasome activation and cholesterol biosynthetic signaling in macrophages C Guo, Z Chi, D Jiang, T Xu, W Yu, Z Wang, S Chen, L Zhang, Q Liu, ... Immunity 49 (5), 842-856. e7, 2018 | 215 | 2018 |
| Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase stimulated by δ-and γ-tocotrienols BL Song, RA DeBose-Boyd Journal of biological chemistry 281 (35), 25054-25061, 2006 | 214 | 2006 |
| Cholesterol modification of smoothened is required for hedgehog signaling X Xiao, JJ Tang, C Peng, Y Wang, L Fu, ZP Qiu, Y Xiong, LF Yang, ... Molecular cell 66 (1), 154-162. e10, 2017 | 207 | 2017 |
| Regulation of glucose and lipid metabolism in health and disease L Chen, XW Chen, X Huang, BL Song, Y Wang, Y Wang Science China life sciences 62, 1420-1458, 2019 | 177 | 2019 |
| Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78 JN Lee, B Song, RA DeBose-Boyd, J Ye Journal of Biological Chemistry 281 (51), 39308-39315, 2006 | 177 | 2006 |
| Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake L Ge, W Qi, LJ Wang, HH Miao, YX Qu, BL Li, BL Song Proceedings of the National Academy of Sciences 108 (2), 551-556, 2011 | 168 | 2011 |
| SREBP: a novel therapeutic target X Xiao, BL Song Acta Biochim Biophys Sin 45 (1), 2-10, 2013 | 162 | 2013 |
| Acyl-CoA: cholesterol acyltransferases (ACATs/SOATs): Enzymes with multiple sterols as substrates and as activators MA Rogers, J Liu, BL Song, BL Li, CCY Chang, TY Chang The Journal of steroid biochemistry and molecular biology 151, 102-107, 2015 | 153 | 2015 |
| Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol SY Jiang, H Li, JJ Tang, J Wang, J Luo, B Liu, JK Wang, XJ Shi, HW Cui, ... Nature Communications 9 (1), 5138, 2018 | 148 | 2018 |
| In vivo AAV-CRISPR/Cas9–mediated gene editing ameliorates atherosclerosis in familial hypercholesterolemia H Zhao, Y Li, L He, W Pu, W Yu, Y Li, YT Wu, C Xu, Y Wei, Q Ding, ... Circulation 141 (1), 67-79, 2020 | 144 | 2020 |
Chang XIEAstellas Gene TherapiesVerified email at ucsf.edu
