| E2F1 confers anticancer drug resistance by targeting ABC transporter family members and Bcl-2 via the p73/DNp73-miR-205 circuitry V Alla, BS Kowtharapu, D Engelmann, S Emmrich, U Schmitz, M Steder, ... Cell cycle 11 (16), 3067-3078, 2012 | 88 | 2012 |
| Regulation of cell cycle checkpoint kinase WEE1 by miR-195 in malignant melanoma A Bhattacharya, U Schmitz, O Wolkenhauer, M Schönherr, Y Raatz, ... Oncogene 32 (26), 3175-3183, 2013 | 85 | 2013 |
| Computational analysis of target hub gene repression regulated by multiple and cooperative miRNAs X Lai, U Schmitz, SK Gupta, A Bhattacharya, M Kunz, O Wolkenhauer, ... Nucleic Acids Research, 2012 | 72 | 2012 |
| Cooperative gene regulation by microRNA pairs and their identification using a computational workflow U Schmitz, X Lai, F Winter, O Wolkenhauer, J Vera, SK Gupta Nucleic acids research 42 (12), 7539-7552, 2014 | 67 | 2014 |
| MicroRNA–mRNA interactions in colorectal cancer and their role in tumor progression R Amirkhah, U Schmitz, M Linnebacher, O Wolkenhauer, A Farazmand Genes, Chromosomes and Cancer 54 (3), 129-141, 2015 | 66 | 2015 |
| E2F1 induces miR‐224/452 expression to drive EMT through TXNIP downregulation S Knoll, K Fürst, B Kowtharapu, U Schmitz, S Marquardt, O Wolkenhauer, ... EMBO reports 15 (12), 1315-1329, 2014 | 65 | 2014 |
| miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy A Bhattacharya, U Schmitz, Y Raatz, M Schönherr, T Kottek, M Schauer, ... Oncotarget 6 (5), 2966, 2015 | 62 | 2015 |
| MicroRNA-Regulated Networks: The Perfect Storm for Classical Molecular Biology, the Ideal Scenario for Systems Biology. J Vera, X Lai, U Schmitz, O Wolkenhauer Advances in experimental medicine and biology 774, 55, 2013 | 56 | 2013 |
| A dynamic intron retention program in the mammalian megakaryocyte and erythrocyte lineages CR Edwards, W Ritchie, JJL Wong, U Schmitz, R Middleton, X An, ... Blood, The Journal of the American Society of Hematology 127 (17), e24-e34, 2016 | 50 | 2016 |
| Kinetic Modeling–Based Detection of Genetic Signatures That Provide Chemoresistance via the E2F1-p73/DNp73-miR-205 Network J Vera, U Schmitz, X Lai, D Engelmann, FM Khan, O Wolkenhauer, ... Cancer research 73 (12), 3511-3524, 2013 | 48 | 2013 |
| Tumor-promoting role of signal transducer and activator of transcription (Stat) 1 in late-stage melanoma growth J Schultz, D Koczan, U Schmitz, SM Ibrahim, D Pilch, J Landsberg, ... Clinical and Experimental Metastasis 27 (3), 133-140, 2010 | 46 | 2010 |
| Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures FM Khan, S Marquardt, SK Gupta, S Knoll, U Schmitz, A Spitschak, ... Nature communications 8 (1), 1-15, 2017 | 45 | 2017 |
| TRAPLINE: a standardized and automated pipeline for RNA sequencing data analysis, evaluation and annotation M Wolfien, C Rimmbach, U Schmitz, JJ Jung, S Krebs, G Steinhoff, ... BMC bioinformatics 17 (1), 1-11, 2016 | 38 | 2016 |
| Systems biology-based investigation of cooperating microRNAs as monotherapy or adjuvant therapy in cancer X Lai, M Eberhardt, U Schmitz, J Vera Nucleic acids research 47 (15), 7753-7766, 2019 | 35 | 2019 |
| MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance X Lai, SK Gupta, U Schmitz, S Marquardt, S Knoll, A Spitschak, ... Theranostics 8 (4), 1106, 2018 | 34 | 2018 |
| Intron retention enhances gene regulatory complexity in vertebrates U Schmitz, N Pinello, F Jia, S Alasmari, W Ritchie, MC Keightley, S Shini, ... Genome biology 18 (1), 1-15, 2017 | 33 | 2017 |
| RBM3 regulates temperature sensitive miR-142–5p and miR-143 (thermomiRs), which target immune genes and control fever JJL Wong, AYM Au, D Gao, N Pinello, CT Kwok, A Thoeng, KA Lau, ... Nucleic acids research 44 (6), 2888-2897, 2016 | 33 | 2016 |
| 2‐DE profiling of GDNF overexpression‐related proteome changes in differentiating ST14A rat progenitor cells R Hoffrogge, S Beyer, R Hübner, S Mikkat, E Mix, C Scharf, U Schmitz, ... Proteomics 7 (1), 33-46, 2007 | 32 | 2007 |
| MicroRNA and transcription factor gene regulatory network analysis reveals key regulatory elements associated with prostate cancer progression M Sadeghi, B Ranjbar, MR Ganjalikhany, F M. Khan, U Schmitz, ... PloS one 11 (12), e0168760, 2016 | 31 | 2016 |
| Challenges in defining the role of intron retention in normal biology and disease DP Vanichkina, U Schmitz, JJL Wong, JEJ Rasko Seminars in cell & developmental biology 75, 40-49, 2018 | 29 | 2018 |
Julio Vera-GonzálezProfessor of Medical Systems Biology, University Hospital Erlangen, FAU Erlangen-Nürnberg, DZIBestätigte E-Mail-Adresse bei uk-erlangen.de
