| Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis RL Levine, M Wadleigh, J Cools, BL Ebert, G Wernig, BJP Huntly, ... Cancer cell 7 (4), 387-397, 2005 | 3814 | 2005 |
| A Tyrosine Kinase Created by Fusion of the PDGFRA and FIP1L1 Genes as a Therapeutic Target of Imatinib in Idiopathic Hypereosinophilic Syndrome J Cools, DJ DeAngelo, J Gotlib, EH Stover, RD Legare, J Cortes, J Kutok, ... New England Journal of Medicine 348 (13), 1201-1214, 2003 | 2147 | 2003 |
| The roles of FLT3 in hematopoiesis and leukemia DG Gilliland, JD Griffin Blood, The Journal of the American Society of Hematology 100 (5), 1532-1542, 2002 | 2024 | 2002 |
| Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl E Weisberg, PW Manley, W Breitenstein, J Brüggen, SW Cowan-Jacob, ... Cancer cell 7 (2), 129-141, 2005 | 1919 | 2005 |
| Nilotinib in imatinib-resistant CML and Philadelphia chromosome–positive ALL H Kantarjian, F Giles, L Wunderle, K Bhalla, S O'Brien, B Wassmann, ... New England Journal of Medicine 354 (24), 2542-2551, 2006 | 1633 | 2006 |
| Granulocyte colony-stimulating factor and its receptor GD Demetri, JD Griffin | 1388 | 1991 |
| The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element JA DeCaprio, JW Ludlow, D Lynch, Y Furukawa, J Griffin, ... Cell 58 (6), 1085-1095, 1989 | 1191 | 1989 |
| STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications DA Tuveson, NA Willis, T Jacks, JD Griffin, S Singer, CDM Fletcher, ... Oncogene 20 (36), 5054-5058, 2001 | 875 | 2001 |
| Effect of recombinant human granulocyte-macrophage colony-stimulating factor on chemotherapy-induced myelosuppression KS Antman, JD Griffin, A Elias, MA Socinski, L Ryan, SA Cannistra, ... New England Journal of Medicine 319 (10), 593-598, 1988 | 847 | 1988 |
| Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412 RM Stone, DJ DeAngelo, V Klimek, I Galinsky, E Estey, SD Nimer, ... Blood 105 (1), 54-60, 2005 | 843 | 2005 |
| Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia E Weisberg, PW Manley, SW Cowan-Jacob, A Hochhaus, JD Griffin Nature Reviews Cancer 7 (5), 345-356, 2007 | 814 | 2007 |
| Reduction of experimental canine myocardial reperfusion injury by a monoclonal antibody (anti-Mo1, anti-CD11b) that inhibits leukocyte adhesion. PJ Simpson, RF Todd, JC Fantone, JK Mickelson, JD Griffin, BR Lucchesi The Journal of clinical investigation 81 (2), 624-629, 1988 | 809 | 1988 |
| Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412 E Weisberg, C Boulton, LM Kelly, P Manley, D Fabbro, T Meyer, ... Cancer cell 1 (5), 433-443, 2002 | 734 | 2002 |
| Granulocyte-macrophage colony stimulating factor expands the circulating haemopoietic progenitor cell compartment in man MA Socinski, A Elias, L Schnipper, SA Cannistra, KH Antman, JD Griffin The Lancet 331 (8596), 1194-1198, 1988 | 729 | 1988 |
| MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors L Wu, JC Aster, SC Blacklow, R Lake, S Artavanis-Tsakonas, JD Griffin Nature genetics 26 (4), 484-489, 2000 | 723 | 2000 |
| Expression of myeloid differentiation antigens on normal and malignant myeloid cells. JD Griffin, J Ritz, LM Nadler, SF Schlossman The Journal of clinical investigation 68 (4), 932-941, 1981 | 628 | 1981 |
| t (11; 19)(q21; p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway G Tonon, S Modi, L Wu, A Kubo, AB Coxon, T Komiya, K O'Neil, K Stover, ... Nature genetics 33 (2), 208-213, 2003 | 618 | 2003 |
| Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl. N Carlesso, DA Frank, JD Griffin The Journal of experimental medicine 183 (3), 811-820, 1996 | 610 | 1996 |
| AMN107 (nilotinib): a novel and selective inhibitor of BCR-ABL E Weisberg, P Manley, J Mestan, S Cowan-Jacob, A Ray, JD Griffin British journal of cancer 94 (12), 1765-1769, 2006 | 593 | 2006 |
| JAK2 associates with the βc chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region FW Quelle, N Sato, BA Witthuhn, RC Inhorn, M Eder, A Miyajima, ... Molecular and cellular biology, 1994 | 591 | 1994 |
