Accelerated Evolution of the ASPM Gene Controlling Brain Size Begins Prior to Human Brain Expansion N Kouprina, A Pavlicek, GH Mochida, G Solomon, W Gersch, YH Yoon, ... PLoS biology 2 (5), e126, 2004 | 240 | 2004 |
Selective isolation of genomic loci from complex genomes by transformation-associated recombination cloning in the yeast Saccharomyces cerevisiae N Kouprina, V Larionov Nature protocols 3 (3), 371-377, 2008 | 229 | 2008 |
The microcephaly ASPM gene is expressed in proliferating tissues and encodes for a mitotic spindle protein N Kouprina, A Pavlicek, NK Collins, M Nakano, VN Noskov, JI Ohzeki, ... Human molecular genetics 14 (15), 2155-2165, 2005 | 223 | 2005 |
Specific cloning of human DNA as yeast artificial chromosomes by transformation-associated recombination. V Larionov, N Kouprina, J Graves, XN Chen, JR Korenberg, MA Resnick Proceedings of the National Academy of Sciences 93 (1), 491-496, 1996 | 203 | 1996 |
Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP‐A assembly J Ohzeki, JH Bergmann, N Kouprina, VN Noskov, M Nakano, H Kimura, ... The EMBO journal 31 (10), 2391-2402, 2012 | 181 | 2012 |
Highly efficient CRISPR/Cas9-mediated TAR cloning of genes and chromosomal loci from complex genomes in yeast NCO Lee, V Larionov, N Kouprina Nucleic acids research 43 (8), e55-e55, 2015 | 141 | 2015 |
TAR cloning: insights into gene function, long-range haplotypes and genome structure and evolution N Kouprina, V Larionov Nature Reviews Genetics 7 (10), 805-812, 2006 | 139 | 2006 |
Transformation-associated recombination (TAR) cloning for genomics studies and synthetic biology N Kouprina, V Larionov Chromosoma 125, 621-632, 2016 | 125 | 2016 |
Refined human artificial chromosome vectors for gene therapy and animal transgenesis Y Kazuki, H Hoshiya, M Takiguchi, S Abe, Y Iida, M Osaki, M Katoh, ... Gene therapy 18 (4), 384-393, 2011 | 124 | 2011 |
Evolution of the tumor suppressor BRCA1 locus in primates: implications for cancer predisposition A Pavlicek, VN Noskov, N Kouprina, JC Barrett, J Jurka, V Larionov Human Molecular Genetics 13 (22), 2737-2751, 2004 | 116 | 2004 |
3D-CLEM reveals that a major portion of mitotic chromosomes is not chromatin DG Booth, AJ Beckett, O Molina, I Samejima, H Masumoto, N Kouprina, ... Molecular cell 64 (4), 790-802, 2016 | 114 | 2016 |
Direct isolation of human BRCA2 gene by transformation-associated recombination in yeast V Larionov, N Kouprina, G Solomon, JC Barrett, MA Resnick Proceedings of the National Academy of Sciences 94 (14), 7384-7387, 1997 | 107 | 1997 |
CTF4 (CHL15) mutants exhibit defective DNA metabolism in the yeast Saccharomyces cerevisiae. LV Kouprina N, Kroll E, Bannikov V, Bliskovsky V, Gizatullin R, Kirillov A ... Mol Cell Biol. 12 (12), 5736-47, 1992 | 107 | 1992 |
The human telomerase gene: complete genomic sequence and analysis of tandem repeat polymorphisms in intronic regions SH Leem, JA Londono-Vallejo, JH Kim, H Bui, E Tubacher, G Solomon, ... Oncogene 21 (5), 769-777, 2002 | 103 | 2002 |
Discovery of a novel, paternally expressed ubiquitin-specific processing protease gene through comparative analysis of an imprinted region of mouse chromosome 7 and human … J Kim, VN Noskov, X Lu, A Bergmann, X Ren, T Warth, P Richardson, ... Genome research 10 (8), 1138-1147, 2000 | 95 | 2000 |
A new generation of human artificial chromosomes for functional genomics and gene therapy N Kouprina, WC Earnshaw, H Masumoto, V Larionov Cellular and Molecular Life Sciences 70, 1135-1148, 2013 | 88 | 2013 |
Cloning of human centromeres by transformation‐associated recombination in yeast and generation of functional human artificial chromosomes N Kouprina, T Ebersole, M Koriabine, E Pak, IB Rogozin, M Katoh, ... Nucleic acids research 31 (3), 922-934, 2003 | 87 | 2003 |
Human artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells JH Kim, A Kononenko, I Erliandri, TA Kim, M Nakano, Y Iida, JC Barrett, ... Proceedings of the National Academy of Sciences 108 (50), 20048-20053, 2011 | 85 | 2011 |
Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing JH Kim, T Ebersole, N Kouprina, VN Noskov, JI Ohzeki, H Masumoto, ... Genome research 19 (4), 533-544, 2009 | 85 | 2009 |
Functional copies of a human gene can be directly isolated by transformation-associated recombination cloning with a small 3′ end target sequence N Kouprina, L Annab, J Graves, C Afshari, JC Barrett, MA Resnick, ... Proceedings of the National Academy of Sciences 95 (8), 4469-4474, 1998 | 84 | 1998 |