X-ray structure of 12-oxophytodienoate reductase 1 provides structural insight into substrate binding and specificity within the family of OYE C Breithaupt, J Strassner, U Breitinger, R Huber, P Macheroux, A Schaller, ... Structure 9 (5), 419-429, 2001 | 144 | 2001 |
Viroporins and inflammasomes: a key to understand virus-induced inflammation NS Farag, U Breitinger, HG Breitinger, MA El Azizi The international journal of biochemistry & cell biology 122, 105738, 2020 | 115 | 2020 |
The three-dimensional structure of cystathionine β-lyase from Arabidopsis and its substrate specificity U Breitinger, T Clausen, S Ehlert, R Huber, B Laber, F Schmidt, E Pohl, ... Plant physiology 126 (2), 631-642, 2001 | 67 | 2001 |
Viroporins: Structure, function, and their role in the life cycle of SARS-CoV-2 U Breitinger, NS Farag, H Sticht, HG Breitinger The international journal of biochemistry & cell biology 145, 106185, 2022 | 46 | 2022 |
The p7 viroporin of the hepatitis C virus contributes to liver inflammation by stimulating production of Interleukin-1β NS Farag, U Breitinger, M El-Azizi, HG Breitinger Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (3), 712-720, 2017 | 40 | 2017 |
Inhibition of SARS CoV envelope protein by flavonoids and classical viroporin inhibitors U Breitinger, NKM Ali, H Sticht, HG Breitinger Frontiers in microbiology 12, 692423, 2021 | 39 | 2021 |
Conserved high affinity ligand binding and membrane association in the native and refolded extracellular domain of the human glycine receptor α1-subunit U Breitinger, HG Breitinger, F Bauer, K Fahmy, D Glockenhammer, ... Journal of Biological Chemistry 279 (3), 1627-1636, 2004 | 39 | 2004 |
Synergistic Inhibition of Glycinergic Transmission In Vitro and In Vivo by Flavonoids and Strychnine K Raafat, U Breitinger, L Mahran, N Ayoub, HG Breitinger Toxicological Sciences 118 (1), 171-182, 2010 | 36 | 2010 |
Novel regulatory site within the TM3–4 loop of human recombinant α3 glycine receptors determines channel gating and domain structure HG Breitinger, C Villmann, N Melzer, J Rennert, U Breitinger, ... Journal of Biological Chemistry 284 (42), 28624-28633, 2009 | 32 | 2009 |
Modulators of the inhibitory glycine receptor U Breitinger, HG Breitinger ACS Chemical Neuroscience 11 (12), 1706-1725, 2020 | 31 | 2020 |
PKA and PKC modulators affect ion channel function and internalization of recombinant alpha1 and alpha1-beta glycine receptors U Breitinger, LM Bahnassawy, D Janzen, V Roemer, CM Becker, ... Frontiers in molecular neuroscience 11, 154, 2018 | 29 | 2018 |
Patch-clamp study of hepatitis C p7 channels reveals genotype-specific sensitivity to inhibitors U Breitinger, NS Farag, NKM Ali, HGA Breitinger Biophysical journal 110 (11), 2419-2429, 2016 | 25 | 2016 |
Molecular dynamics simulation links conformation of a pore-flanking region to hyperekplexia-related dysfunction of the inhibitory glycine receptor HG Breitinger, H Lanig, C Vohwinkel, C Grewer, U Breitinger, T Clark, ... Chemistry & biology 11 (10), 1339-1350, 2004 | 24 | 2004 |
Glucose is a positive modulator for the activation of human recombinant glycine receptors U Breitinger, KM Raafat, HG Breitinger Journal of neurochemistry 134 (6), 1055-1066, 2015 | 23 | 2015 |
Distinct Proteins in Protein Corona of Nanoparticles Represent a Promising Venue for Endogenous Targeting–Part I: In vitro Release and Intracellular Uptake Perspective AA Sebak, IEO Gomaa, AN ElMeshad, MH Farag, U Breitinger, ... International journal of nanomedicine, 8845-8862, 2020 | 19 | 2020 |
Augmentation of glycine receptor alpha3 currents suggests a mechanism for glucose-mediated analgesia U Breitinger, HG Breitinger Neuroscience Letters 612, 110-115, 2016 | 19 | 2016 |
Distinct proteins in protein corona of nanoparticles represent a promising venue for endogenous targeting–part ii: In vitro and in vivo kinetics study AA Sebak, IEO Gomaa, AN ElMeshad, MH Farag, U Breitinger, ... International Journal of Nanomedicine, 9539-9556, 2020 | 18 | 2020 |
Kavalactones from Kava (Piper methysticum) root extract as modulators of recombinant human glycine receptors NH Hegazy, HG Breitinger, U Breitinger Biological chemistry 400 (9), 1205-1215, 2019 | 15 | 2019 |
Modulation of recombinant human α1 glycine receptors by mono-and disaccharides: a kinetic study U Breitinger, H Sticht, HG Breitinger ACS Chemical Neuroscience 7 (8), 1077-1087, 2016 | 15 | 2016 |
Delivery of trans-membrane proteins by liposomes; the effect of liposome size and formulation technique on the efficiency of protein delivery M Sakla, U Breitinger, HG Breitinger, S Mansour, SN Tammam International Journal of Pharmaceutics 606, 120879, 2021 | 14 | 2021 |