| Therapeutics based on stop codon readthrough KM Keeling, X Xue, G Gunn, DM Bedwell Annual review of genomics and human genetics 15, 371-394, 2014 | 339 | 2014 |
| Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression B Roy, WJ Friesen, Y Tomizawa, JD Leszyk, J Zhuo, B Johnson, J Dakka, ... Proceedings of the National Academy of Sciences 113 (44), 12508-12513, 2016 | 218 | 2016 |
| Synthetic Aminoglycosides Efficiently Suppress CFTR Nonsense Mutations and are Enhanced by Ivacaftor X Xue, V Mutyam, L Tang, S Biswas, M Du, LA Jackson, Y Dai, ... American journal of respiratory cell and molecular biology, 2013 | 169* | 2013 |
| Synthetic aminoglycosides efficiently suppress cystic fibrosis transmembrane conductance regulator nonsense mutations and are enhanced by ivacaftor X Xue, V Mutyam, L Tang, S Biswas, M Du, LA Jackson, Y Dai, ... American journal of respiratory cell and molecular biology 50 (4), 805-816, 2014 | 163 | 2014 |
| Discovery of clinically approved agents that promote suppression of cystic fibrosis transmembrane conductance regulator nonsense mutations V Mutyam, M Du, X Xue, KM Keeling, EL White, JR Bostwick, ... American journal of respiratory and critical care medicine 194 (9), 1092-1103, 2016 | 96 | 2016 |
| Identification of the amino acids inserted during suppression of CFTR nonsense mutations and determination of their functional consequences X Xue, V Mutyam, A Thakerar, J Mobley, RJ Bridges, SM Rowe, ... Human molecular genetics 26 (16), 3116-3129, 2017 | 87 | 2017 |
| The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential WJ Friesen, B Johnson, J Sierra, J Zhuo, P Vazirani, X Xue, Y Tomizawa, ... PLoS One 13 (10), e0206158, 2018 | 47 | 2018 |
| J Bridges R, Baasov T, Hong J, Bedwell DM, Rowe SM. Synthetic aminoglycosides efficiently suppress cystic fibrosis transmembrane conductance regulator nonsense mutations and … X Xue, V Mutyam, L Tang, S Biswas, M Du, LA Jackson, Y Dai, ... American Journal of Respiratory Cell and Molecular Biology 50, 805-816, 2014 | 11 | 2014 |
| Ataluren suppresses a premature termination codon in an MPS IH mouse D Wang, X Xue, G Gunn, M Du, A Siddiqui, M Weetall, KM Keeling Journal of Molecular Medicine 100 (8), 1223-1235, 2022 | 6 | 2022 |
| Cloning, purification, crystallization and preliminary crystallographic analysis of the tandem tudor domain of Sgf29 from Saccharomyces cerevisiae J Li, X Xue, J Ruan, M Wu, Z Zhu, J Zang Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010 | 6 | 2010 |
| Guanidino quinazolines and pyrimidines promote readthrough of premature termination codons in cells with native nonsense mutations C Morrill, WJ Friesen, S Babu, RY Baiazitov, W Du, DB Karloff, CS Lee, ... Bioorganic & Medicinal Chemistry Letters 76, 128989, 2022 | 5 | 2022 |
| The synthetic aminoglycoside NB124 suppresses cftr premature termination codons more effectively than gentamicin and prior synthetic derivatives SM Rowe, L Tang, X Xue, S Biswas, M Du, V Belakhov, J Kandasamy, ... PEDIATRIC PULMONOLOGY 47, 290-290, 2012 | 2 | 2012 |
| IDENTIFICATION OF A CLINICALLY APPROVED AGENT THAT EFFICIENTLY PROMOTES THE SUPPRESSION OF PREMATURE TERMINATION CODONS IN CFTR NONSENSE MUTATIONS V Mutyam, M Du, B Liu, X Xue, EL White, R Bostwick, L Rasmussen, ... PEDIATRIC PULMONOLOGY 50, 273-273, 2015 | 1 | 2015 |
| IDENTIFICATION AND FUNCTIONAL ANALYSIS OF THE ALTERNATE AMINO ACIDS INSERTED AT CFTR PREMATURE STOP CODONS DURING NONSENSE SUPPRESSION X Xue, V Mutyam, J Mobley, M Du, SM Rowe, DM Bedwell PEDIATRIC PULMONOLOGY 50, 280-281, 2015 | 1 | 2015 |
| 268 Identifying the amino acid (s) inserted upon premature termination codon readthrough and their effect on CFTR functionality K Thrasher, J Chen, L Fu, X Xue, D Benson, J Ekstrom, K Keeling, ... Journal of Cystic Fibrosis 22, S135-S136, 2023 | | 2023 |
| 610 Evaluating the mechanism of amino acid insertion upon readthrough of cystic fibrosis transmembrane conductance regulator nonsense mutations K Thrasher, X Xue, D Benson, J Chen, M Renfrow, K Keeling, S Rowe, ... Journal of Cystic Fibrosis 21, S338-S339, 2022 | | 2022 |
| 606: Evaluating protein variants created by readthrough of CFTR nonsense mutations K Thrasher, X Xue, D Benson, M Renfrow, K Keeling, D Bedwell Journal of Cystic Fibrosis 20, S288-S289, 2021 | | 2021 |
| EVALUATING THE CFTR PROTEIN VARIANTS CREATED UPON READTHROUGH K Thrasher, X Xue, D Benson, J Mobley, MB Renfrow, KM Keeling, ... PEDIATRIC PULMONOLOGY 55, S240-S240, 2020 | | 2020 |
| IDENTIFICATION OF AMINO ACIDS INCORPORATED DURING SUPPRESSION OF CFTR NONSENSE MUTATIONS K Thrasher, X Xue, D Benson, J Mobley, MB Renfrow, KM Keeling, ... PEDIATRIC PULMONOLOGY 54, S201-S201, 2019 | | 2019 |
| INSIGHTS INTO THE MECHANISM OF AMINO ACID SELECTION DURING SUPPRESSION OF CFTR NONSENSE MUTATIONS K Thrasher, X Xue, D Benson, V Mutyam, J Mobley, PA Thakerar, ... PEDIATRIC PULMONOLOGY 53, 166-167, 2018 | | 2018 |
