An environment-dependent transcriptional network specifies human microglia identity D Gosselin, D Skola, NG Coufal, IR Holtman, JCM Schlachetzki, E Sajti, ... Science 356 (6344), eaal3222, 2017 | 1123 | 2017 |
Brain cell type–specific enhancer–promoter interactome maps and disease-risk association A Nott, IR Holtman, NG Coufal, JCM Schlachetzki, M Yu, R Hu, CZ Han, ... Science 366 (6469), 1134-1139, 2019 | 604 | 2019 |
Frontotemporal dementia and its subtypes: a genome-wide association study R Ferrari, DG Hernandez, MA Nalls, JD Rohrer, A Ramasamy, JBJ Kwok, ... The Lancet Neurology 13 (7), 686-699, 2014 | 415 | 2014 |
Microbiome–microglia connections via the gut–brain axis R Abdel-Haq, JCM Schlachetzki, CK Glass, SK Mazmanian Journal of Experimental Medicine 216 (1), 41-59, 2019 | 392 | 2019 |
Wearable sensors objectively measure gait parameters in Parkinson’s disease JCM Schlachetzki, J Barth, F Marxreiter, J Gossler, Z Kohl, S Reinfelder, ... PloS one 12 (10), e0183989, 2017 | 347 | 2017 |
Liver-derived signals sequentially reprogram myeloid enhancers to initiate and maintain Kupffer cell identity M Sakai, TD Troutman, JS Seidman, Z Ouyang, NJ Spann, Y Abe, KM Ego, ... Immunity 51 (4), 655-670. e8, 2019 | 313 | 2019 |
Unbiased and mobile gait analysis detects motor impairment in Parkinson's disease J Klucken, J Barth, P Kugler, J Schlachetzki, T Henze, F Marxreiter, Z Kohl, ... PloS one 8 (2), e56956, 2013 | 285 | 2013 |
Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients J Mertens, JR Herdy, L Traxler, ST Schafer, JCM Schlachetzki, L Böhnke, ... Cell stem cell 28 (9), 1533-1548. e6, 2021 | 190 | 2021 |
Oxidative stress-induced posttranslational modifications of alpha-synuclein: specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity W Xiang, JCM Schlachetzki, S Helling, JC Bussmann, M Berlinghof, ... Molecular and Cellular Neuroscience 54, 71-83, 2013 | 188 | 2013 |
Oligodendroglia and myelin in neurodegenerative diseases: more than just bystanders? B Ettle, JCM Schlachetzki, J Winkler Molecular neurobiology 53, 3046-3062, 2016 | 153 | 2016 |
Granulocyte‐colony stimulating factor is neuroprotective in a model of Parkinson's disease K Meuer, C Pitzer, P Teismann, C Krüger, B Göricke, R Laage, P Lingor, ... Journal of neurochemistry 97 (3), 675-686, 2006 | 142 | 2006 |
Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases R Ferrari, Y Wang, J Vandrovcova, S Guelfi, A Witeolar, CM Karch, ... Journal of Neurology, Neurosurgery & Psychiatry 88 (2), 152-164, 2017 | 135 | 2017 |
Studying neurodegenerative diseases in culture models J Schlachetzki, SW Saliba, ACP Oliveira Brazilian Journal of Psychiatry 35, S92-S100, 2013 | 133 | 2013 |
Alpha-synuclein activates BV2 microglia dependent on its aggregation state A Hoffmann, B Ettle, A Bruno, A Kulinich, AC Hoffmann, J von Wittgenstein, ... Biochemical and Biophysical Research Communications 479 (4), 881-886, 2016 | 125 | 2016 |
Mitochondrial aging defects emerge in directly reprogrammed human neurons due to their metabolic profile Y Kim, X Zheng, Z Ansari, MC Bunnell, JR Herdy, L Traxler, H Lee, ... Cell reports 23 (9), 2550-2558, 2018 | 124 | 2018 |
Microglial activation in Alzheimer's disease J Schlachetzki, M Hull Current Alzheimer Research 6 (6), 554-563, 2009 | 116 | 2009 |
Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons DA Reid, PJ Reed, JCM Schlachetzki, II Nitulescu, G Chou, EC Tsui, ... Science 372 (6537), 91-94, 2021 | 93 | 2021 |
An in vivo neuroimmune organoid model to study human microglia phenotypes ST Schafer, AAF Mansour, JCM Schlachetzki, M Pena, S Ghassemzadeh, ... Cell 186 (10), 2111-2126. e20, 2023 | 92 | 2023 |
Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer’s disease L Traxler, JR Herdy, D Stefanoni, S Eichhorner, S Pelucchi, A Szücs, ... Cell metabolism 34 (9), 1248-1263. e6, 2022 | 91 | 2022 |
APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia MS Haney, R Pálovics, CN Munson, C Long, PK Johansson, O Yip, ... Nature 628 (8006), 154-161, 2024 | 87 | 2024 |