Johannes Schlachetzki
Johannes Schlachetzki
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An environment-dependent transcriptional network specifies human microglia identity
D Gosselin, D Skola, NG Coufal, IR Holtman, JCM Schlachetzki, E Sajti, ...
Science 356 (6344), eaal3222, 2017
Brain cell type–specific enhancer–promoter interactome maps and disease-risk association
A Nott, IR Holtman, NG Coufal, JCM Schlachetzki, M Yu, R Hu, CZ Han, ...
Science 366 (6469), 1134-1139, 2019
Frontotemporal dementia and its subtypes: a genome-wide association study
R Ferrari, DG Hernandez, MA Nalls, JD Rohrer, A Ramasamy, JBJ Kwok, ...
The Lancet Neurology 13 (7), 686-699, 2014
Microbiome–microglia connections via the gut–brain axis
R Abdel-Haq, JCM Schlachetzki, CK Glass, SK Mazmanian
Journal of Experimental Medicine 216 (1), 41-59, 2019
Wearable sensors objectively measure gait parameters in Parkinson’s disease
JCM Schlachetzki, J Barth, F Marxreiter, J Gossler, Z Kohl, S Reinfelder, ...
PloS one 12 (10), e0183989, 2017
Liver-derived signals sequentially reprogram myeloid enhancers to initiate and maintain Kupffer cell identity
M Sakai, TD Troutman, JS Seidman, Z Ouyang, NJ Spann, Y Abe, KM Ego, ...
Immunity 51 (4), 655-670. e8, 2019
Unbiased and mobile gait analysis detects motor impairment in Parkinson's disease
J Klucken, J Barth, P Kugler, J Schlachetzki, T Henze, F Marxreiter, Z Kohl, ...
PloS one 8 (2), e56956, 2013
Oxidative stress-induced posttranslational modifications of alpha-synuclein: specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity
W Xiang, JCM Schlachetzki, S Helling, JC Bussmann, M Berlinghof, ...
Molecular and Cellular Neuroscience 54, 71-83, 2013
Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients
J Mertens, JR Herdy, L Traxler, ST Schafer, JCM Schlachetzki, L Böhnke, ...
Cell stem cell 28 (9), 1533-1548. e6, 2021
Oligodendroglia and myelin in neurodegenerative diseases: more than just bystanders?
B Ettle, JCM Schlachetzki, J Winkler
Molecular neurobiology 53, 3046-3062, 2016
Granulocyte‐colony stimulating factor is neuroprotective in a model of Parkinson's disease
K Meuer, C Pitzer, P Teismann, C Krüger, B Göricke, R Laage, P Lingor, ...
Journal of neurochemistry 97 (3), 675-686, 2006
Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases
R Ferrari, Y Wang, J Vandrovcova, S Guelfi, A Witeolar, CM Karch, ...
Journal of Neurology, Neurosurgery & Psychiatry 88 (2), 152-164, 2017
Studying neurodegenerative diseases in culture models
J Schlachetzki, SW Saliba, ACP Oliveira
Brazilian Journal of Psychiatry 35, S92-S100, 2013
Mitochondrial aging defects emerge in directly reprogrammed human neurons due to their metabolic profile
Y Kim, X Zheng, Z Ansari, MC Bunnell, JR Herdy, L Traxler, H Lee, ...
Cell reports 23 (9), 2550-2558, 2018
Alpha-synuclein activates BV2 microglia dependent on its aggregation state
A Hoffmann, B Ettle, A Bruno, A Kulinich, AC Hoffmann, J von Wittgenstein, ...
Biochemical and Biophysical Research Communications 479 (4), 881-886, 2016
Microglial activation in Alzheimer's disease
J Schlachetzki, M Hull
Current Alzheimer Research 6 (6), 554-563, 2009
Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons
DA Reid, PJ Reed, JCM Schlachetzki, II Nitulescu, G Chou, EC Tsui, ...
Science 372 (6537), 91-94, 2021
Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer’s disease
L Traxler, JR Herdy, D Stefanoni, S Eichhorner, S Pelucchi, A Szücs, ...
Cell metabolism 34 (9), 1248-1263. e6, 2022
α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy
B Ettle, BE Kerman, E Valera, C Gillmann, JCM Schlachetzki, S Reiprich, ...
Acta neuropathologica 132, 59-75, 2016
Pathogenic huntingtin repeat expansions in patients with frontotemporal dementia and amyotrophic lateral sclerosis
R Dewan, R Chia, J Ding, RA Hickman, TD Stein, Y Abramzon, S Ahmed, ...
Neuron 109 (3), 448-460. e4, 2021
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