Nuria Morral
Nuria Morral
Indiana University School of Medicine
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Zitiert von
Zitiert von
Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity
G Schiedner, N Morral, RJ Parks, Y Wu, SC Koopmans, C Langston, ...
Nature genetics 18 (2), 180-183, 1998
Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons
N Morral, W O’Neal, K Rice, M Leland, J Kaplan, PA Piedra, H Zhou, ...
Proceedings of the National Academy of Sciences 96 (22), 12816-12821, 1999
The origin of the major cystic fibrosis mutation (ΔF508) in European populations
N Morral, J Bertranpetit, X Estivill, V Nunes, T Casals, J Gimenez, A Reis, ...
Nature genetics 7 (2), 169-175, 1994
High doses of a helper-dependent adenoviral vector yield supraphysiological levels of α 1-antitrypsin with negligible toxicity
N Morral, RJ Parks, H Zhou, C Langston, G Schiedner, J Quinones, ...
Human gene therapy 9 (18), 2709-2716, 1998
Use of a liver-specific promoter reduces immune response to the transgene in adenoviral vectors
L Pastore, N Morral, H Zhou, R Garcia, RJ Parks, S Kochanek, FL Graham, ...
Human gene therapy 10 (11), 1773-1781, 1999
Immune responses to reporter proteins and high viral dose limit duration of expression with adenoviral vectors: comparison of E2a wild type and E2a deleted vectors
N Morral, W O'Neal, H Zhou, C Langston, A Beaudet
Human gene therapy 8 (10), 1275-1286, 1997
Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons
N Morral, WK O'Neal, K Rice, MM Leland, PA Piedra, E Aguilar-Córdova, ...
Human gene therapy 13 (1), 143-154, 2002
Sterol regulatory element-binding protein-1 (SREBP-1) is required to regulate glycogen synthesis and gluconeogenic gene expression in mouse liver
R Ruiz, V Jideonwo, M Ahn, S Surendran, VS Tagliabracci, Y Hou, ...
Journal of Biological Chemistry 289 (9), 5510-5517, 2014
Toxicological Comparison of E2a-Deleted and First-Generation Adenoviral Vectors Expressing α1-Antitrypsin after Systemic Delivery
WK O'Neal, H Zhou, N Morral, E Aguilar-Cordova, J Pestaner, C Langston, ...
Human gene therapy 9 (11), 1587-1598, 1998
The search for south European cystic fibrosis mutations: identification of two new mutations, four variants, and intronic sequences
P Gasparini, V Nunes, A Savoia, M Dognini, N Morral, A Gaona, ...
Genomics 10 (1), 193-200, 1991
Development of a complementing cell line and a system for construction of adenovirus vectors with E1 and E2a deleted
H Zhou, W O'Neal, N Morral, AL Beaudet
Journal of virology 70 (10), 7030-7038, 1996
CAGT Microsatellite alleles within the cystic fibrosis transmembrane conductance regulator (CFTR) gene are not generated by unequal crossingover
N Morral, V Nunes, T Casals, X Estivill
Genomics 10 (3), 692-698, 1991
Microsatellite haplotypes for cystic fibrosis: mutation frameworks and evolutionary tracers
N Morral, V Nunes, T Casals, M Chillón, J Giménez, J Bertranpetit, ...
Human molecular genetics 2 (7), 1015-1022, 1993
Toxicity associated with repeated administration of first-generation adenovirus vectors does not occur with a helper-dependent vector
WK O’Neal, H Zhou, N Morral, C Langston, RJ Parks, FL Graham, ...
Molecular medicine 6, 179-195, 2000
Multiplex PCR amplification of three microsatellites within the CFTR gene
N Morral, X Estivill
Genomics 13 (4), 1362-1364, 1992
Gene therapy for inherited retinal and optic nerve degenerations
NA Moore, N Morral, TA Ciulla, P Bracha
Expert Opinion on Biological Therapy 18 (1), 37-49, 2018
Molecular cloning and analysis of a yeast protein phosphatase with an unusual amino-terminal region.
F Posas, A Casamayor, N Morral, J Ariño
Journal of Biological Chemistry 267 (17), 11734-11740, 1992
Novel targets and therapeutic strategies for type 2 diabetes
N Morral
Trends in Endocrinology & Metabolism 14 (4), 169-175, 2003
Analysis of the CFTR gene confirms the high genetic heterogeneity of the Spanish population: 43 mutations account for only 78% of CF chromosomes
M Chillón, T Casals, J Giménez, MD Ramos, A Palacio, N Morral, X Estivill, ...
Human genetics 93, 447-451, 1994
Gene therapy for age-related macular degeneration
NA Moore, P Bracha, RM Hussain, N Morral, TA Ciulla
Expert opinion on biological therapy 17 (10), 1235-1244, 2017
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