Timothy E Shutt
Timothy E Shutt
University of Calgary
Verified email at dal.ca
Cited by
Cited by
Bacteriophage origins of mitochondrial replication and transcription proteins
TE Shutt, MW Gray
Trends in Genetics 22 (2), 90-95, 2006
The intracellular redox state is a core determinant of mitochondrial fusion
T Shutt, M Geoffrion, R Milne, HM McBride
EMBO reports 13 (10), 909-915, 2012
Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness
N Raimundo, L Song, TE Shutt, SE McKay, J Cotney, MX Guan, ...
Cell 148 (4), 716-726, 2012
Ancient mtDNA genetic variants modulate mtDNA transcription and replication
S Suissa, Z Wang, J Poole, S Wittkopp, J Feder, TE Shutt, DC Wallace, ...
PLoS Genet 5 (5), e1000474, 2009
Staying cool in difficult times: mitochondrial dynamics, quality control and the stress response
TE Shutt, HM McBride
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (2), 417-424, 2013
A compendium of human mitochondrial gene expression machinery with links to disease
TE Shutt, GS Shadel
Environmental and molecular mutagenesis 51 (5), 360-379, 2010
Core human mitochondrial transcription apparatus is a regulated two-component system in vitro
TE Shutt, MF Lodeiro, J Cotney, CE Cameron, GS Shadel
Proceedings of the National Academy of Sciences 107 (27), 12133-12138, 2010
Twinkle, the mitochondrial replicative DNA helicase, is widespread in the eukaryotic radiation and may also be the mitochondrial DNA primase in most eukaryotes
TE Shutt, MW Gray
Journal of molecular evolution 62 (5), 588-599, 2006
ROMO1 is an essential redox-dependent regulator of mitochondrial dynamics
M Norton, ACH Ng, S Baird, A Dumoulin, T Shutt, N Mah, ...
Science signaling 7 (310), ra10-ra10, 2014
An ancient spliceosomal intron in the ribosomal protein L7a gene (Rpl7a) of Giardia lamblia
AG Russell, TE Shutt, RF Watkins, MW Gray
BMC evolutionary biology 5 (1), 45, 2005
Mitochondrial ribosomal protein L12 selectively associates with human mitochondrial RNA polymerase to activate transcription
YV Surovtseva, TE Shutt, J Cotney, H Cimen, SY Chen, EC Koc, ...
Proceedings of the National Academy of Sciences 108 (44), 17921-17926, 2011
Homologs of mitochondrial transcription factor B, sparsely distributed within the eukaryotic radiation, are likely derived from the dimethyladenosine methyltransferase of the …
TE Shutt, MW Gray
Molecular biology and evolution 23 (6), 1169-1179, 2006
The Keap1–Nrf2 stress response pathway promotes mitochondrial hyperfusion through degradation of the mitochondrial fission protein Drp1
R Sabouny, E Fraunberger, M Geoffrion, ACH Ng, SD Baird, RA Screaton, ...
Antioxidants & redox signaling 27 (18), 1447-1459, 2017
The core human mitochondrial transcription initiation complex: It only takes two to tango
TE Shutt, M Bestwick, GS Shadel
Transcription 2 (2), 55-59, 2011
The mitochondrial division inhibitor Mdivi-1 rescues mammalian neurons from anesthetic-induced cytotoxicity
F Xu, R Armstrong, D Urrego, M Qazzaz, M Pehar, JN Armstrong, T Shutt, ...
Molecular brain 9 (1), 1-13, 2016
Expanding the mitochondrial interactome
TE Shutt, GS Shadel
Genome biology 8 (2), 203, 2007
PISD is a mitochondrial disease gene causing skeletal dysplasia, cataracts, and white matter changes
T Zhao, CM Goedhart, PN Sam, R Sabouny, S Lingrell, AJ Cornish, ...
Life science alliance 2 (2), 2019
Tissue specific impacts of a ketogenic diet on mitochondrial dynamics in the BTBRT+ tf/j mouse
C Newell, TE Shutt, Y Ahn, D Hittel, A Khan, JM Rho, J Shearer
Frontiers in physiology 7, 654, 2016
The R941L mutation in MYH14 disrupts mitochondrial fission and associates with peripheral neuropathy
W Almutawa, C Smith, R Sabouny, RB Smit, T Zhao, R Wong, ...
EBioMedicine 45, 379-392, 2019
Mesenchymal stem cells shift mitochondrial dynamics and enhance oxidative phosphorylation in recipient cells
C Newell, R Sabouny, D Hittel, TE Shutt, A Khan, MS Klein, J Shearer
Frontiers in physiology 9, 1572, 2018
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