Voltage-sensing residues in the S2 and S4 segments of the Shaker K+ channel SA Seoh, D Sigg, DM Papazian, F Bezanilla neuron 16 (6), 1159-1167, 1996 | 856 | 1996 |
Bilayer reconstitution of voltage-dependent ion channels using a microfabricated silicon chip R Pantoja, D Sigg, R Blunck, F Bezanilla, JR Heath Biophysical Journal 81 (4), 2389-2394, 2001 | 167 | 2001 |
Total charge movement per channel: the relation between gating charge displacement and the voltage sensitivity of activation D Sigg, F Bezanilla The Journal of general physiology 109 (1), 27-39, 1997 | 134 | 1997 |
Voltage Gating of Shaker K+ Channels: The Effect of Temperature on Ionic and Gating Currents BM Rodríguez, D Sigg, F Bezanilla The Journal of general physiology 112 (2), 223-242, 1998 | 124 | 1998 |
Gating current noise produced by elementary transitions in Shaker potassium channels D Sigg, E Stefani, F Bezanilla Science 264 (5158), 578-582, 1994 | 111 | 1994 |
Fast gating in the Shaker K+ channel and the energy landscape of activation D Sigg, F Bezanilla, E Stefani Proceedings of the National Academy of Sciences 100 (13), 7611-7615, 2003 | 89 | 2003 |
Functional heterogeneity of the four voltage sensors of a human L-type calcium channel A Pantazis, N Savalli, D Sigg, A Neely, R Olcese Proceedings of the National Academy of Sciences 111 (51), 18381-18386, 2014 | 86 | 2014 |
Kramers’ diffusion theory applied to gating kinetics of voltage-dependent ion channels D Sigg, H Qian, F Bezanilla Biophysical Journal 76 (2), 782-803, 1999 | 85 | 1999 |
Modeling ion channels: Past, present, and future D Sigg Journal of General Physiology 144 (1), 7-26, 2014 | 82 | 2014 |
The α2δ-1 subunit remodels CaV1.2 voltage sensors and allows Ca2+ influx at physiological membrane potentials N Savalli, A Pantazis, D Sigg, JN Weiss, A Neely, R Olcese Journal of General Physiology 148 (2), 147-159, 2016 | 59 | 2016 |
Quantifying transient ischemic dilation using gated SPECT TF Heston, DM Sigg Journal of Nuclear Medicine 46 (12), 1990-1996, 2005 | 53 | 2005 |
Regulation of K+ Flow by a Ring of Negative Charges in the Outer Pore of BKCa Channels. Part I: Aspartate 292 modulates K+ Conduction by External Surface … T Haug, D Sigg, S Ciani, L Toro, E Stefani, R Olcese The Journal of general physiology 124 (2), 173-184, 2004 | 49 | 2004 |
The contribution of RCK domains to human BK channel allosteric activation N Savalli, A Pantazis, T Yusifov, D Sigg, R Olcese Journal of Biological Chemistry 287 (26), 21741-21750, 2012 | 48 | 2012 |
Operation of the voltage sensor of a human voltage-and Ca2+-activated K+ channel A Pantazis, V Gudzenko, N Savalli, D Sigg, R Olcese Proceedings of the National Academy of Sciences 107 (9), 4459-4464, 2010 | 48 | 2010 |
A physical model of potassium channel activation: from energy landscape to gating kinetics D Sigg, F Bezanilla Biophysical journal 84 (6), 3703-3716, 2003 | 46 | 2003 |
A Conducting State with Properties of a Slow Inactivated State in a Shaker K+ Channel Mutant R Olcese, D Sigg, R Latorre, F Bezanilla, E Stefani The Journal of general physiology 117 (2), 149-164, 2001 | 36 | 2001 |
A linkage analysis toolkit for studying allosteric networks in ion channels D Sigg Journal of General Physiology 141 (1), 29-60, 2013 | 24 | 2013 |
Exploring the complex dynamics of an ion channel voltage sensor domain via computation L Delemotte, MA Kasimova, D Sigg, ML Klein, V Carnevale, M Tarek BioRxiv, 108217, 2017 | 13 | 2017 |
Correlation between the early component of gating current and total gating current in Shaker K channels E Stefani, D Sigg, F Bezanilla Biophysical Journal 78 (1), 7A-7A, 2000 | 10 | 2000 |
Silicon-wafer based devices and methods for analyzing biological material J Heath, R Pantoja, F Bezanilla, D Sigg US Patent App. 10/473,784, 2004 | 8 | 2004 |