A new antibiotic kills pathogens without detectable resistance LL Ling, T Schneider, AJ Peoples, AL Spoering, I Engels, BP Conlon, ... Nature 517 (7535), 455-459, 2015 | 2816 | 2015 |
Plectasin, a fungal defensin, targets the bacterial cell wall precursor Lipid II T Schneider, T Kruse, R Wimmer, I Wiedemann, V Sass, U Pag, A Jansen, ... Science 328 (5982), 1168-1172, 2010 | 581 | 2010 |
Daptomycin inhibits cell envelope synthesis by interfering with fluid membrane microdomains A Müller, M Wenzel, H Strahl, F Grein, TNV Saaki, B Kohl, T Siersma, ... Proceedings of the National Academy of Sciences 113 (45), E7077-E7086, 2016 | 407 | 2016 |
Mechanisms of daptomycin resistance in Staphylococcus aureus: role of the cell membrane and cell wall AS Bayer, T Schneider, HG Sahl Annals of the New York Academy of Sciences 1277 (1), 139-158, 2013 | 395 | 2013 |
Human β-defensin 3 inhibits cell wall biosynthesis in Staphylococci V Sass, T Schneider, M Wilmes, C Körner, A Tossi, N Novikova, ... Infection and immunity 78 (6), 2793-2800, 2010 | 309 | 2010 |
An oldie but a goodie–cell wall biosynthesis as antibiotic target pathway T Schneider, HG Sahl International Journal of Medical Microbiology 300 (2-3), 161-169, 2010 | 303 | 2010 |
In vitro assembly of a complete, pentaglycine interpeptide bridge containing cell wall precursor (lipid II‐Gly5) of Staphylococcus aureus T Schneider, MM Senn, B Berger‐Bächi, A Tossi, HG Sahl, I Wiedemann Molecular microbiology 53 (2), 675-685, 2004 | 221 | 2004 |
Insights into in vivo activities of lantibiotics from gallidermin and epidermin mode-of-action studies RR Bonelli, T Schneider, HG Sahl, I Wiedemann Antimicrobial agents and chemotherapy 50 (4), 1449-1457, 2006 | 211 | 2006 |
MprF-mediated biosynthesis of lysylphosphatidylglycerol, an important determinant in staphylococcal defensin resistance P Staubitz, H Neumann, T Schneider, I Wiedemann, A Peschel FEMS microbiology letters 231 (1), 67-71, 2004 | 208 | 2004 |
The lipopeptide antibiotic Friulimicin B inhibits cell wall biosynthesis through complex formation with bactoprenol phosphate T Schneider, K Gries, M Josten, I Wiedemann, S Pelzer, H Labischinski, ... Antimicrobial agents and chemotherapy 53 (4), 1610-1618, 2009 | 184 | 2009 |
Ca2+-Daptomycin targets cell wall biosynthesis by forming a tripartite complex with undecaprenyl-coupled intermediates and membrane lipids F Grein, A Müller, KM Scherer, X Liu, KC Ludwig, A Klöckner, M Strach, ... Nature communications 11 (1), 1455, 2020 | 175 | 2020 |
Copsin, a novel peptide-based fungal antibiotic interfering with the peptidoglycan synthesis A Essig, D Hofmann, D Münch, S Gayathri, M Künzler, PT Kallio, HG Sahl, ... Journal of Biological Chemistry 289 (50), 34953-34964, 2014 | 168 | 2014 |
Insight into invertebrate defensin mechanism of action: oyster defensins inhibit peptidoglycan biosynthesis by binding to lipid II P Schmitt, M Wilmes, M Pugnière, A Aumelas, E Bachère, HG Sahl, ... Journal of Biological Chemistry 285 (38), 29208-29216, 2010 | 155 | 2010 |
Identification and in vitro Analysis of the GatD/MurT Enzyme-Complex Catalyzing Lipid II Amidation in Staphylococcus aureus D Münch, T Roemer, SH Lee, M Engeser, HG Sahl, T Schneider PLoS pathogens 8 (1), e1002509, 2012 | 136 | 2012 |
Specific interaction of the unmodified bacteriocin Lactococcin 972 with the cell wall precursor lipid II B Martínez, T Böttiger, T Schneider, A Rodríguez, HG Sahl, ... Applied and environmental microbiology 74 (15), 4666-4670, 2008 | 130 | 2008 |
Cyclic lipopeptides as antibacterial agents–potent antibiotic activity mediated by intriguing mode of actions T Schneider, A Müller, H Miess, H Gross International Journal of Medical Microbiology 304 (1), 37-43, 2014 | 118 | 2014 |
Dual targeting of cell wall precursors by teixobactin leads to cell lysis T Homma, A Nuxoll, AB Gandt, P Ebner, I Engels, T Schneider, F Götz, ... Antimicrobial agents and chemotherapy 60 (11), 6510-6517, 2016 | 104 | 2016 |
Lipid II-based antimicrobial activity of the lantibiotic plantaricin C I Wiedemann, T Böttiger, RR Bonelli, T Schneider, HG Sahl, B Martínez Applied and environmental microbiology 72 (4), 2809-2814, 2006 | 101 | 2006 |
Eurocin, a new fungal defensin: structure, lipid binding, and its mode of action JS Oeemig, C Lynggaard, DH Knudsen, FT Hansen, KD Nørgaard, ... Journal of Biological Chemistry 287 (50), 42361-42372, 2012 | 98 | 2012 |
Targeting a cell wall biosynthesis hot spot A Müller, A Klöckner, T Schneider Natural product reports 34 (7), 909-932, 2017 | 93 | 2017 |