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Lia Luus
Lia Luus
Bicycle Therapeutics
Verified email at bicycletx.com
Title
Cited by
Cited by
Year
Antitumor activity of a novel bispecific antibody that targets the ErbB2/ErbB3 oncogenic unit and inhibits heregulin-induced activation of ErbB3
CF McDonagh, A Huhalov, BD Harms, S Adams, V Paragas, S Oyama, ...
Molecular cancer therapeutics 11 (3), 582-593, 2012
3432012
Novel arylsulfoanilide− oxindole hybrid as an anticancer agent that inhibits translation initiation
A Natarajan, Y Guo, F Harbinski, YH Fan, H Chen, L Luus, J Diercks, ...
Journal of medicinal chemistry 47 (21), 4979-4982, 2004
1892004
Single-cell quantitative HER2 measurement identifies heterogeneity and distinct subgroups within traditionally defined HER2-positive patients
MD Onsum, E Geretti, V Paragas, AJ Kudla, SP Moulis, L Luus, ...
The American journal of pathology 183 (5), 1446-1460, 2013
822013
Synthesis and biological evaluation of thiazolidine-2, 4-dione and 2, 4-thione derivatives as inhibitors of translation initiation
H Chen, YH Fan, A Natarajan, Y Guo, J Iyasere, F Harbinski, L Luus, ...
Bioorganic & medicinal chemistry letters 14 (21), 5401-5405, 2004
682004
Characterization of the immunologic responses to human in vivo acquired enamel pellicle as a novel means to investigate its composition.
J Li, EJ Helmerhorst, RB Corley, LE Luus, RF Troxler, FG Oppenheim
Oral Microbiology & Immunology 18 (3), 2003
542003
Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse models
WS Kamoun, DB Kirpotin, ZR Huang, SK Tipparaju, CO Noble, ME Hayes, ...
Nature Biomedical Engineering 3 (4), 264-280, 2019
442019
Antibody-mediated targeting of TNFR2 activates CD8+ T cells in mice and promotes antitumor immunity
EM Tam, RB Fulton, JF Sampson, M Muda, A Camblin, J Richards, ...
Science translational medicine 11 (512), eaax0720, 2019
422019
Nanoliposome targeting in breast cancer is influenced by the tumor microenvironment
N Dumont, S Merrigan, J Turpin, C Lavoie, V Papavasiliou, E Geretti, ...
Nanomedicine: Nanotechnology, Biology and Medicine 17, 71-81, 2019
272019
Synergy between EphA2-ILs-DTXp, a novel EphA2-targeted nanoliposomal taxane, and PD-1 inhibitors in preclinical tumor models
WS Kamoun, AS Dugast, JJ Suchy, S Grabow, RB Fulton, JF Sampson, ...
Molecular Cancer Therapeutics 19 (1), 270-281, 2020
162020
MM-111, an ErbB2/ErbB3 bispecific antibody with potent activity in ErbB2-overexpressing cells, positively combines with trastuzumab to inhibit growth of breast cancer cells …
A Huhalov, S Adams, V Paragas, S Oyama, R Overland, L Luus, ...
Cancer Research 70 (8_Supplement), 3485-3485, 2010
162010
Disruption of membrane cholesterol stimulates MyD88-dependent NF-κB activation in immature B cells
JA Flemming, KH Perkins, L Luus, AR Ferguson, RB Corley
Cellular immunology 229 (1), 68-77, 2004
152004
Targeting EphA2 in bladder cancer using a novel antibody-directed nanotherapeutic
W Kamoun, E Swindell, C Pien, L Luus, J Cain, M Pham, I Kandela, ...
Pharmaceutics 12 (10), 996, 2020
82020
MM-111: a novel bispecific antibody targeting ErbB3 with potent anti-tumor activity in ErbB2 over-expressing malignancies.
U Nielsen, A Huhalov, B Harms, V Paragas, S Adams, J Gu, S Nguyen, ...
Cancer Research 69 (2_Supplement), 4166, 2009
82009
Discovery and optimization of a synthetic class of nectin-4-targeted CD137 agonists for immuno-oncology
P Upadhyaya, J Kristensson, J Lahdenranta, E Repash, J Ma, J Kublin, ...
Journal of Medicinal Chemistry 65 (14), 9858-9872, 2022
72022
IgM monomers accelerate disease manifestations in autoimmune-prone Fas-deficient mice
ME Youd, L Luus, RB Corley
Journal of autoimmunity 23 (4), 333-343, 2004
72004
MM-401, a novel anti-TNFR2 antibody that induces T cell co-stimulation, robust anti-tumor activity and immune memory
J Richards, C Wong, A Koshkaryev, R Fulton, A Camblin, J Sampson, ...
Cancer Res 79 (13 Supplement), 4846, 2019
62019
Prediction of xenograft response to MM-121, an anti-ErbB3 inhibitor, using computational modeling and measurements of five biomarkers
M Onsum, O Burenkova, A Fulgham, L Nie, A Kalra, D Xiao, ...
Cancer Research 70 (8_Supplement), 3756-3756, 2010
62010
Abstract# 5472: MM-111: A novel ErbB3 antagonist with potent antitumor activity in ErbB2 over-expressing malignancies
A Huhalov, S Adams, J Gu, B Harms, V Paragas, L Luus, S Nguyen, ...
Cancer Research 69 (9_Supplement), 5472-5472, 2009
52009
Selective inhibition of integrin αvβ6 leads to rapid induction of urinary bladder tumors in cynomolgus macaques
M Guffroy, B Trela, T Kambara, L Stawski, H Chen, L Luus, ...
Toxicological Sciences 191 (2), 400-413, 2023
42023
Abstract P1-07-03: Quantification of HER2 expression at the single cell level and HER2 intratumoral heterogeneity of breast cancer tissue samples using automated image analysis
E Geretti, V Paragas, M Onsum, A Kudla, S Moulis, L Luus, T Wickham, ...
Cancer Research 72 (24_Supplement), P1-07-03-P1-07-03, 2012
42012
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