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Olivia R. Asfaha
Olivia R. Asfaha
R&D in Biotechnology Startups
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Phosphorylation of Ser1928 mediates the enhanced activity of the L-type Ca2+ channel Cav1.2 by the β2-adrenergic receptor in neurons
H Qian, T Patriarchi, JL Price, L Matt, B Lee, M Nieves-Cintrón, ...
Science signaling 10 (463), eaaf9659, 2017
1122017
Ser1928 phosphorylation by PKA stimulates the L-type Ca2+ channel CaV1.2 and vasoconstriction during acute hyperglycemia and diabetes
MA Nystoriak, M Nieves-Cintrón, T Patriarchi, OR Buonarati, MP Prada, ...
Science signaling 10 (463), eaaf9647, 2017
1092017
Mechanisms of postsynaptic localization of AMPA-type glutamate receptors and their regulation during long-term potentiation
OR Buonarati, EA Hammes, JF Watson, IH Greger, JW Hell
Science signaling 12 (562), eaar6889, 2019
772019
Phosphorylation of Cav1.2 on S1928 uncouples the L‐type Ca2+ channel from the β2 adrenergic receptor
T Patriarchi, H Qian, V Di Biase, ZA Malik, D Chowdhury, JL Price, ...
The EMBO journal 35 (12), 1330-1345, 2016
702016
Postsynaptic localization and regulation of AMPA receptors and Cav1.2 by β2 adrenergic receptor/PKA and Ca2+/CaMKII signaling
T Patriarchi, OR Buonarati, JW Hell
The EMBO journal 37 (20), e99771, 2018
692018
α-Actinin anchors PSD-95 at postsynaptic sites
L Matt, K Kim, AC Hergarden, T Patriarchi, ZA Malik, DK Park, ...
Neuron 97 (5), 1094-1109. e9, 2018
692018
Cardiomyocyte substructure reverts to an immature phenotype during heart failure
DB Lipsett, M Frisk, JM Aronsen, ES Norden, OR Buonarati, A Cataliotti, ...
The Journal of physiology 597 (7), 1833-1853, 2019
482019
CaMKII holoenzyme mechanisms that govern the LTP versus LTD decision
SG Cook, OR Buonarati, SJ Coultrap, KU Bayer
Science Advances 7 (16), eabe2300, 2021
472021
CaMKII versus DAPK1 binding to GluN2B in ischemic neuronal cell death after resuscitation from cardiac arrest
OR Buonarati, SG Cook, DJ Goodell, NE Chalmers, NL Rumian, JE Tullis, ...
Cell reports 30 (1), 1-8. e4, 2020
422020
A Gs-coupled purinergic receptor boosts Ca2+ influx and vascular contractility during diabetic hyperglycemia
MP Prada, AU Syed, OR Buonarati, GR Reddy, MA Nystoriak, D Ghosh, ...
Elife 8, e42214, 2019
422019
Impaired BKCa channel function in native vascular smooth muscle from humans with type 2 diabetes
M Nieves-Cintrón, AU Syed, OR Buonarati, RR Rigor, MA Nystoriak, ...
Scientific reports 7 (1), 14058, 2017
412017
Proteolytic processing of the L-type Ca 2+ channel alpha 11.2 subunit in neurons
OR Buonarati, PB Henderson, GG Murphy, MC Horne, JW Hell
F1000Research 6, 2017
242017
Conserved and divergent features of neuronal CaMKII holoenzyme structure, function, and high-order assembly
OR Buonarati, AP Miller, SJ Coultrap, KU Bayer, SL Reichow
Cell reports 37 (13), 2021
212021
GluN2B S1303 phosphorylation by CaMKII or DAPK1: no indication for involvement in ischemia or LTP
JE Tullis, OR Buonarati, SJ Coultrap, AM Bourke, EL Tiemeier, ...
Iscience 24 (10), 2021
102021
Stimulating β-adrenergic receptors promotes synaptic potentiation by switching CaMKII movement from LTD to LTP mode
ME Larsen, OR Buonarati, H Qian, JW Hell, KU Bayer
Journal of Biological Chemistry 299 (6), 2023
32023
Short-term CaMKII inhibition with tatCN19o does not erase pre-formed memory in mice and is neuroprotective in pigs
NL Rumian, CN Brown, TB Hendry-Hofer, T Rossetti, JE Orfila, JE Tullis, ...
Journal of Biological Chemistry 299 (5), 2023
22023
Short-term CaMKII inhibition with tatCN19o does not erase pre-formed memory and is neuroprotective in non-rodents
NL Rumian, CN Brown, TB Hendry-Hofer, T Rossetti, JE Orfila, JE Tullis, ...
bioRxiv, 2023
2023
CaMKII binding to GluN2B flips a β-adrenergic switch from synaptic depression to potentiation
OR Buonarati, ME Larsen, H Qian, JW Hell, KU Bayer
bioRxiv, 2022.06. 23.497296, 2022
2022
A Gs-coupled purinergic receptor boosts Ca2+ influx and vascular contractility during
MP Prada, AU Syed, OR Buonarati
2019
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