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Jaklien Leemans
Jaklien Leemans
Scientist MMC - Associate Professor AMC - PI Lunet
Bestätigte E-Mail-Adresse bei mmc.nl
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Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
SS Iyer, WP Pulskens, JJ Sadler, LM Butter, GJ Teske, TK Ulland, ...
Proceedings of the National Academy of Sciences 106 (48), 20388-20393, 2009
8142009
Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney
JC Leemans, G Stokman, N Claessen, KM Rouschop, GJD Teske, ...
The Journal of clinical investigation 115 (10), 2894-2903, 2005
6702005
Alveolar macrophages have a protective antiinflammatory role during murine pneumococcal pneumonia
S Knapp, JC Leemans, S Florquin, J Branger, NA Maris, J Pater, ...
American journal of respiratory and critical care medicine 167 (2), 171-179, 2003
4262003
Role oftoll-like receptor 4 in gram-positive and gram-negative pneumonia inmice
J Branger, S Knapp, S Weijer, JC Leemans, JM Pater, P Speelman, ...
Infection and immunity 72 (2), 788-794, 2004
3342004
Sensing damage by the NLRP3 inflammasome
JC Leemans, SL Cassel, FS Sutterwala
Immunological reviews 243 (1), 152-162, 2011
3232011
Toll-like receptor-4 coordinates the innate immune response of the kidney to renal ischemia/reperfusion injury
WP Pulskens, GJ Teske, LM Butter, JJ Roelofs, T Van Der Poll, S Florquin, ...
PloS one 3 (10), e3596, 2008
3022008
Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice
JC Leemans, NP Juffermans, S Florquin, N van Rooijen, ...
The journal of immunology 166 (7), 4604-4611, 2001
2752001
Hydrogen sulfide-induced hypometabolism prevents renal ischemia/reperfusion injury
EM Bos, HGD Leuvenink, PM Snijder, NJ Kloosterhuis, JL Hillebrands, ...
Journal of the American Society of Nephrology 20 (9), 1901-1905, 2009
2142009
TREM-1 and its potential ligands in non-infectious diseases: from biology to clinical perspectives
A Tammaro, M Derive, S Gibot, JC Leemans, S Florquin, MC Dessing
Pharmacology & therapeutics 177, 81-95, 2017
2102017
Toll‐like receptor 4 plays a protective role in pulmonary tuberculosis in mice
J Branger, JC Leemans, S Florquin, S Weijer, P Speelman, T Van Der Poll
International immunology 16 (3), 509-516, 2004
1842004
TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury
WP Pulskens, E Rampanelli, GJ Teske, LM Butter, N Claessen, IK Luirink, ...
Journal of the American Society of Nephrology 21 (8), 1299-1308, 2010
1832010
Pattern recognition receptors and the inflammasome in kidney disease
JC Leemans, L Kors, HJ Anders, S Florquin
Nature Reviews Nephrology 10 (7), 398-414, 2014
1822014
CD44 is a macrophage binding site for Mycobacterium tuberculosis that mediates macrophage recruitment and protective immunity against tuberculosis
JC Leemans, S Florquin, M Heikens, ST Pals, R Van der Neut, ...
The Journal of clinical investigation 111 (5), 681-689, 2003
1632003
Pulmonary Mycobacterium tuberculosis infection in leptin-deficient ob/ob mice
CW Wieland, S Florquin, ED Chan, JC Leemans, S Weijer, A Verbon, ...
International immunology 17 (11), 1399-1408, 2005
1582005
The role of Toll-like receptor 2 in inflammation and fibrosis during progressive renal injury
JC Leemans, LM Butter, WPC Pulskens, GJD Teske, N Claessen, ...
PloS one 4 (5), e5704, 2009
1522009
The role of Toll-like receptor 2 in inflammation and fibrosis during progressive renal injury
JC Leemans, LM Butter, WPC Pulskens, GJD Teske, N Claessen, ...
PloS one 4 (5), e5704, 2009
1522009
The epidermal growth factor-seven transmembrane (EGF-TM7) receptor CD97 is required for neutrophil migration and host defense
JC Leemans, AA te Velde, S Florquin, RJ Bennink, K de Bruin, ...
The Journal of Immunology 172 (2), 1125-1131, 2004
1492004
Ventilator-induced lung injury is mediated by the NLRP3 inflammasome
MT Kuipers, H Aslami, JR Janczy, KF van der Sluijs, APJ Vlaar, ...
The Journal of the American Society of Anesthesiologists 116 (5), 1104-1115, 2012
1422012
Differential role of interleukin-6 in lung inflammation induced by lipoteichoic acid and peptidoglycan from Staphylococcus aureus
JC Leemans, MJBM Vervoordeldonk, S Florquin, KP van Kessel, ...
American journal of respiratory and critical care medicine 165 (10), 1445-1450, 2002
1392002
Depletion of gut microbiota protects against renal ischemia-reperfusion injury
D Emal, E Rampanelli, I Stroo, LM Butter, GJ Teske, N Claessen, ...
Journal of the American Society of Nephrology 28 (5), 1450-1461, 2017
1292017
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